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alexandrelaliberte.bsky.social

@alexandrelaliberte.bsky.social

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Reposted by @alexandrelaliberte.bsky.social

Konstantin Sparrer @sparrerlab.bsky.social · 12/12/2025

Our story showing that HIV-1 Nef inhibits actin-mediated innate immune sensing is now out in @natcomms.nature.com. Awesome work by @alexandrelaliberte.bsky.social @caterinaprelli.bsky.social. Great collaboration with Frank Kirchhoff/Michaela Gack/Oliver Fackler. Thanks @dfg.de @bmftr! rdcu.be/eTFJh

Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors

Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...

alexandrelaliberte.bsky.social @alexandrelaliberte.bsky.social · 12/12/2025

Excited to share our new paper and a new Nef function ! rdcu.be/eTFJh Thanks to everyone involved! @caterinaprelli.bsky.social @sparrerlab.bsky.social #hiv #Nef #innateimmunity #sensing #rlr #research

Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors

Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...

Reposted by @alexandrelaliberte.bsky.social

caterinaprelli.bsky.social @caterinaprelli.bsky.social · 05/03/2025

Honored to receive the DZIF Doctoral Award of the @gesvirologie.bsky.social – It is a great motivation to keep going with my scientific career. Thank you @sparrerlab.bsky.social for the amazing words, I feel so grateful! Big thanks also to Frank Kirchhoff and @alexandrelaliberte.bsky.social !