Modern microscopy generates data volumes that far exceed human analytical capacity. Over the past decade, artificial intelligence (AI) has transformed microscopy image analysis into an engine for quan...

Ouellette et al. report that a 16p11.2 deletion induces a bioenergetic failure in brain endothelial cells. Activation of purinergic signaling via P2Y2 receptors restored endothelial function and impro...

Ning Xu - Abnormal beating of airway cilia from a child with Primary Ciliary Dyskinesia (PCD), a genetic disorder affecting respiratory function.

Unlike adult humans, zebrafish can regenerate their hearts after injury. After cardiac injury, the epicardium is rapidly activated to contribute both signaling factors and progenitor cells that are es...

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

Astrocytes are the most numerous brain cells and are central to the regulation of brain metabolism. Here, we present a protocol for identifying molecular signatures and assessing the metabolic functio...

Abstract. The Zebrafish Information Network (zfin.org) is the central repository for Danio rerio genetic and genomic data. The Zebrafish Information Networ

This searchable gallery includes entries for fish families of the world, which may include photographs of preserved specimens, reconstructed CT and photogrammetry 3D models, xrays, characteristics for...

Kim, Geiger et al. report that early-life stress increases the chromatin modification H3K4me1 and its enzymatic writer, SETD7, in the ventral tegmental area. They show that this form of epigenetic pri...

uOttawa, in partnership with the OHRI, invites applications for a Tier 2 CRC in Vascular Links to Neurodevelopment and their impact on brain health.

Are you an ambitious scientist with a background in vascular bioengineering and cell biology? Join our team at Amsterdam UMC and help unravel the mechanisms that govern vascular integrity.

By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University

Antibodies are essential and ubiquitous tools in biology, but their unguarded usage can easily lead to error. Here’s how to validate their specificity, and ensure that they’re hitting the rig…

Neuronal protein tracing, unlike CSF tracers, reveals that brain clearance follows a “nearest exit” principle through distinct border immune niches disrupted differently by disease.

Download Cell Culture and Lab Assistant by Umut Tank on the App Store. See screenshots, ratings and reviews, user tips, and more apps like Cell Culture and Lab…

Download Cell Culture and Lab Assistant by Umut Tank on the App Store. See screenshots, ratings and reviews, user tips, and more apps like Cell Culture and Lab…

ALT: a man holding a briefcase in front of a large building with the words pas mal non c'est francais

A lifesaving injection given at birth to prevent severe bleeding has become collateral damage of the anti-vaccine movement.

Mechanical forces shape the developing heart by controlling cell volume through a Piezo1-driven hydraulic mechanism.

Top predators drive changes in ecosystem structure. For the last ~370 million years, large-sized vertebrates have dominated the apex of the marine food chain, while invertebrates have served as smalle...

Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later.

Here's why you should, and how to start

The feature, which Grammarly shut down Wednesday, presented editing suggestions as if they came from established authors and academics—without their consent.

Kayman Kürekçi et al. show that fibulin-2 regulates epicardial cell activation through nuclear protein 1b signaling to balance fibrosis and regeneration after cardiac injury, and modulating this pathw...