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Total Internal Reflection🇬🇧🇺🇸🇺🇦

@tirscienceblog.bsky.social
426 followers 653 following 527 posts

Blog about the human side of #science, by Brooke Morriswood (formerly Cam Biochem, CIMR,MRC-LMB,Yale, MFPL, UniWue, now #MedComms). Commentary, silliness, & how-to guides for improving young scientists’ soft skills. totalinternalreflectionblog.com

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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 01/10/2026
It’s National Poetry Day today and apparently the 2026 theme is “wonder”. Here’s a piece of doggerel I did a few years ago - a science-orientated poem about miso soup 🤭👇 totalinternalreflectionblog.com/2021/03/18/m...
totalinternalreflectionblog.com
Miso Soup (the origin of life)
Visit the post for more.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/09/2026
New posting! And another more personal one - some reflections on how a career in #MedComms has unexpectedly provided the life of the mind that I was always searching for in #academia.😊👇 totalinternalreflectionblog.com/2026/09/28/a...
totalinternalreflectionblog.com
MedComms offers a true life of the mind
It is a tremendous irony that my present work in MedComms is closer to how I pictured an academic career than academia itself turned out to be.
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Jez Carlton @jezcarlton.bsky.social · 28/09/2026
Hey! Submit your papers, and spread the word, this will be great! Thanks for inviting us @jcellsci.bsky.social and great to work with @pihanson.bsky.social on this issue!
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/09/2026
New posting! And another more personal one - some reflections on how a career in #MedComms has unexpectedly provided the life of the mind that I was always searching for in #academia.😊👇 totalinternalreflectionblog.com/2026/09/28/a...
totalinternalreflectionblog.com
MedComms offers a true life of the mind
It is a tremendous irony that my present work in MedComms is closer to how I pictured an academic career than academia itself turned out to be.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 26/09/2026
Great 🧵 from @hansonmark.bsky.social on why all academics should be opting to publish in non-profit journals 👏👏👏👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 22/09/2026
This article is everything commentary should be - insightful, thought-provoking, informative, & with a framing that both clarifies the situation and stimulates extrapolation from it. You might not agree with everything here, but you should definitely read it (thanks @cyrilpedia.bsky.social!) 👏👏👏😊👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 18/09/2026
Fellow #WordPress bloggers, anyone else getting a weird spike in traffic today? I’ve had a month’s-worth of views in the space of about an hour 🤯, and it’s almost all just to the blog homepage instead of a specific article. Bot traffic maybe? Would love it to be real 🤣 @wordpress.org
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Fran Bottanelli @franbottanelli.bsky.social · 14/09/2026
#membranetrafficking seminars are back for the fall session! This Thursday two exciting talks from Roger Pons Lanau from @felixmendu.bsky.social lab and @veijosalo.bsky.social #ER #lipiddroplets and lots of wonderful imaging! From single molecules to cryo EM! Please repost
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Alondra Nelson @alondra.bsky.social · 10/09/2026
Researchers across the country are turning to side hustles to fund their work. Behind the cuts sits a bigger shift: whether American science can still sustain durable research capacity. @lindseydcameron.bsky.social and I examine the stakes in a new piece @science.org: www.science.org/doi/10.1126/...
science.org
The wrong platform for science
Daniel Blumstein recently sat in a Colorado meadow waiting for yellow-bellied marmots to appear, as the ecologist and evolutionary biologist had done many times before, the New York Times reported. Bu...
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 06/09/2026
Really powerful essay from @angierasmussen.bsky.social on Lysenkoism & the warnings it holds for #NIH & 🇺🇸 science. The comparison isn’t trite: it’s an illustration of what happens when a warped ideology gets coupled to an authoritarian regime 👏👇 rasmussenretorts.substack.com/p/bhattachar...
rasmussenretorts.substack.com
Bhattacharya is the New Lysenko
Starving the NIH through ineptitude, bitterness, and thirst for revenge
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 31/08/2026
@cyrilpedia.bsky.social once again providing great community service by highlighting this really outstanding blog posting on viruses, pandemic viruses, & why AI-designed superviruses are sci-fi and not near-future events. Fascinating, authoritative & insightful 👏👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 24/08/2026
Fascinating @kakape.bsky.social article on the ability of #AI to sway people’s opinions, but there’s 1 nuance I think I missed. In this age of misinformation, we hear over & over again how combating (e.g) conspiracies with facts & rational rebuttal is inefficient /1 www.science.org/content/arti...
science.org
AI chatbots are becoming experts at changing people's minds. What's their secret?
ChatGPT and other AIs use a flood of facts, and the occasional lie, to persuade humans
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Colette Delawalla, PhD @cdelawalla.bsky.social · 23/08/2026
Here’s the thing about the letter supporting one of Dr. Arday’s abusers, every year there is a loud back channel that revs up warning potential students who NOT to apply to for their PhD. When I was applying, I was warned by three women about a prof who raped a student (w/out consequences). 🧵
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 22/08/2026
I’ve taken this survey from @biologists.bsky.social & you should too! 👇 Important to have a discussion about the use of #AI tools in publishing instead of using them & pretending not to…
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 20/08/2026
Agree💯. In the space I inhabit, we’re firewalled off from corporate & marketing, & it’s populated almost exclusively by scientists & physicians developing new therapies or analysing existing ones. Real-world relevance baked into everything, & health improvements paramount. Wonderful environment.😊🤩
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DMM Journal @dmmjournal.bsky.social · 18/08/2026
Are you a PhD student interested in #SciComm, disease biology and publishing? DMM is seeking an intern through BBSRC DTP/PIPS or equivalent schemes Find out about how to apply: www.biologists.com/about-us/wor...
biologists.com
Work for us
Explore career opportunities at The Company of Biologists. Join a team passionate about science, publishing and community support.
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Thiago Carvalho @cyrilpedia.bsky.social · 17/08/2026
Good advice from @tirscienceblog.bsky.social, but I would add: dont try to do this in one slide! 'The general rule for Results slides is “Tell them what you’re going to show them, show them the data, then tell them what they’ve seen”.' network.febs.org/posts/centre...
network.febs.org
Centre stage (a short guide to scientific presentations)
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 17/08/2026
Genuinely one of the most rewarding things about blogging is when an older posting suddenly gets a surge of fresh attention.😊This one, proposing a kind of “jury service” for #newPI scientists on funding panels, is having such a moment. Artwork by Oliver Hoeller👇 wp.me/p76cuy-uv
wp.me
Learning the lingo
Should there be a kind of “jury service” for young faculty on grant funding panels?
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 15/08/2026
If infidelity or other risky behaviours are signs that a relationship is in trouble, what are the social behaviours that indicate a society is in trouble? 🤔
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 11/08/2026
Not a new posting, but a new category of postings! I've now collected all of the enduringly popular #Movember "Great scientists, great moustaches" articles into a single space. The plan is to also provide occasional pieces on men's health. Enjoy!👇 totalinternalreflectionblog.com/2026/08/11/n...
totalinternalreflectionblog.com
New category: Movember, men’s health
One of the most enduringly popular postings – or rather, series of postings – on Total Internal Reflection is “Great scientists, great moustaches”. Posted every November, an…
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 07/08/2026
These tomatoes look like a molecule of water 😂🤪
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 07/08/2026
If I was a Lord Buckethead-type figure running for election to some august scientific body, I would make it a major pillar of my campaign that scientific journal author instructions are 100% CONSISTENT with the requirements on the submission site. And ideally as light as possible.🤬😂
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The Kyiv Independent @kyivindependent.com · 06/08/2026
The story the world likes to hear is that people in Ukraine are resilient and unbreakable. We are resilient. But we are not unbreakable.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 07/08/2026
🚨🚨🚨 #Editor Job alert! I’m not an editor, but if I decided to pursue career in scientific #publishing, then Company of Biologists is the organisation I’d most want to work for, & @jcellsci.bsky.social is the journal I’d want to work at 🤩 Details + link to job description in the link 👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 02/08/2026
#Mastodon query - my account was on #Qoto but I’ve been unable to access it for over a week and have never especially enjoyed the experience there. I know others that have a very positive impression of Mastodon as a whole though. Do I need to change instance? Advice much appreciated.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 02/08/2026
Wonderful 🧵 on Theodor Escherich, who E.coli is named after and whose work has particular relevance in this summer of cyclosporiasis…👏👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 01/08/2026
Excellent article from @jacoates.bsky.social with an admirably clear perspective on the knotty problems enmeshed in the scientific publishing ecosystem. Read it and be enlightened 👏👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 30/07/2026
Here's the latest cross-posting to the @febspress.bsky.social #Network - a riff that was originally written with #academia in mind, but which applies in any line of work really: the difference between good stress and bad stress. network.febs.org/posts/surfin...
network.febs.org
Surfing and drowning (find your breaking point)
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Yasin Dagdas @plantophagy.bsky.social · 29/07/2026
@oeaw.bsky.social is searching for the next #director of @gmivienna.bsky.social ‼️It’s a huge opportunity to shape the future of #plantscience oeawnr.onlyfy.jobs/de/job/u3g5t...
oeawnr.onlyfy.jobs
Scientific Director (f/m/x)
OeAW - Discovering the futureThe Gregor Mendel Institute of Molecular Plant Biology (GMI), part of the Austrian Academy of Sciences (OeAW), is seeking to appoint a visionary Scientific Director to lea
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Prof. Sam Kariuki, BVM, MSc, PhD, DSc (Hons, LSTM) @eadirectordndi.bsky.social · 29/07/2026
Good news! @WHO recommends new treatment guidelines for #leishmaniasis. East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days. South Asia: safer PKDL options, less toxic. Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org
bit.ly
WHO recommends new, better and safer treatment regimens for leishmaniasis
The World Health Organization (WHO) has issued major updates to its leishmaniasis treatment guidelines, introducing a new regimen for visceral leishmaniasis (VL/kala-azar) in eastern Africa and severa...
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/07/2026
With the summer holidays looming, here’s a selection of fiction & nonfiction #books I’ve been #reading recently, with a strong anti-fascism flavour – see if there’s anything that grabs your attention. Have fun, bibliophiles! #BookSky totalinternalreflectionblog.com/2026/07/28/h...
totalinternalreflectionblog.com
Holiday reading 2026
Original artwork by Oliver Hoeller With the summer holidays looming, here’s a selection of fiction & nonfiction books I’ve been reading recently, with a strong anti-fascism flavour – see if the…
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/07/2026
With the summer holidays looming, here’s a selection of fiction & nonfiction #books I’ve been #reading recently, with a strong anti-fascism flavour – see if there’s anything that grabs your attention. Have fun, bibliophiles! #BookSky totalinternalreflectionblog.com/2026/07/28/h...
totalinternalreflectionblog.com
Holiday reading 2026
Original artwork by Oliver Hoeller With the summer holidays looming, here’s a selection of fiction & nonfiction books I’ve been reading recently, with a strong anti-fascism flavour – see if the…
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 27/07/2026
It is always, always such a wonderful sensation when you’re writing a scientific manuscript and you feel it beginning to yield to you ☺️ Having begun with a mound of data, and having sorted it & ruminated on it & struggled with it, & then feeling it start to arrange itself into a narrative…magic🥰
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 23/07/2026
Fantastic 🧵from @carlbergstrom.com analysing the Trump administration’s proposed changes to 🇺🇸science funding. AI grifters seeking institutional capture of the research machinery…🤦‍♂️👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 12/07/2026
Please take 15 min to complete the @elife.bsky.social annual survey and add your voice to the conversation on research culture & scientific communication 👏👇
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 10/07/2026
I smile every time I see this - bravo to @plos.org for having a BlueSky - and no Twitter/X - tab for sharing its content. Small gestures like this send stronger signals than they might at first appear to.👏👏👏
The footer of a PLoS Medicine eTOC. The offered tabs for sharing are BlueSky, Facebook, and LinkedIn. No Twitter/X.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 08/07/2026
“Rather than lamenting known stress points…which merely serve to put oil on the fire of political intervention, suggestions for improvements &cooperation on finding solutions are now required”: admirably pragmatic & clear-headed piece from @berndpulverer.bsky.social link.springer.com/article/10.1...
link.springer.com
Academic independence? - EMBO Reports
EMBO Reports - US federal policies to establish a ‘gold standard science’ threaten to undermine academic freedom. Individual scientists and institutions must re-articulate why the...
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Joachim Mergeay @jmergeay.bsky.social · 02/07/2026
“The Dunning-Kruger effect is one of the key drivers of the American chainsaw massacre, because the anti-science purges are being driven by people who think they could walk into any job and instantly do it well.”
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 01/07/2026
Here's the latest cross-posting (from the vaults!) to the @febspress.bsky.social Network - "Contraception is not the answer!" A riff on why, despite the logjam in academic career options, we should still be seeking to train as many #PhDs as possible. network.febs.org/posts/contra...
network.febs.org
Contraception is not the answer!
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 30/06/2026
New posting! A more whimsical one this time: students reach molecular biology from a variety of sources, but what if we started them off from it instead? What if we went from universality to diversity, instead of the other way around?👇 totalinternalreflectionblog.com/2026/06/30/t...
totalinternalreflectionblog.com
Terms of empowerment
Students reach molecular biology from a variety of sources, but what if we started them off from it instead?
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 30/06/2026
New posting! A more whimsical one this time: students reach molecular biology from a variety of sources, but what if we started them off from it instead? What if we went from universality to diversity, instead of the other way around?👇 totalinternalreflectionblog.com/2026/06/30/t...
totalinternalreflectionblog.com
Terms of empowerment
Students reach molecular biology from a variety of sources, but what if we started them off from it instead?
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/06/2026
I’ve had a protocol request for a paper I published in @elife.bsky.social from someone using an “@research.edu” email address. The request itself seems at least partly machine written, & I can’t find any evidence for an active researcher with the same name on this area. Anyone seen similar?
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 28/06/2026
Another great example of how the #AI hype train is part of a general assault in acquired expertise, & how firms who fully get on hoard with the hype end up regretting it. totalinternalreflectionblog.com/2026/05/12/t...
totalinternalreflectionblog.com
The Dunning-Kruger chainsaw massacre
Just over a year ago, I wrote about the “chainsaw massacre” being perpetrated by Elon Musk and his acolytes at DOGE. At the time, these were the most visible elements – the most visible outrages – …
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 23/06/2026
Can’t vouch for it directly as I haven’t read it, but this book from @labliston.bsky.social sounds like EXACTLY the kind of signposting that we need to provide for young & aspiring scientists of all ages. There’s a multitude of scientific careers out there besides academia 👏👇
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T. Ryan Gregory 🇨🇦 @tryangregory.bsky.social · 22/06/2026
Perfect ("satirical") summary of the AI bubble. The whole thing is gold: www.mcsweeneys.net/articles/ai-...
"Benjamin owns a farm. He employs 100 workers plowing his fields. His total payroll is $10 million/year. One day, he buys a mule, which provides the worker who uses it with a modest 10 percent productivity gain. Benjamin fires 99 of his workers and purchases 99 mules, expecting a 1,000 percent productivity gain. The driverless mules cause plow damage to his property in excess of $50 million. Benjamin loses another $5 million due to the loss of productivity from his one remaining employee, who no longer guides a plow but instead spends 100 percent of his time shoveling mule shit."
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 17/06/2026
Not exactly a “Shock horror!” conclusion in this @nature.com article, but good to see the topic trending. For me though, the piece conflates 2 related but distinct aspects of student training… 🧵/1 www.nature.com/articles/d41...
nature.com
Poor supervision is pushing young researchers out of academia
A survey finds that academic supervisors can have a huge impact on their students’ mental health.
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 07/06/2026
The #ThermoFisher #antibody scandal is an ugly reminder, I think, of how few people (including those at TF, it seems) are trained to properly validate antibodies before use. Some advice on antibody validation in the posting 👇 totalinternalreflectionblog.com/2022/09/18/h...
totalinternalreflectionblog.com
Hitting the target (a short guide to validating antibody specificity)
Antibodies are essential and ubiquitous tools in biology, but their unguarded usage can easily lead to error. Here’s how to validate their specificity, and ensure that they’re hitting the rig…
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Total Internal Reflection🇬🇧🇺🇸🇺🇦 @tirscienceblog.bsky.social · 04/06/2026
With so much doom&gloom&negativity around, I’m finding it really important to focus on 3 things: (1)do things that give me pleasure,(2)always have something to look forward to,(3)find and appreciate beauty. These wonderful photos definitely tick the 3rd box😊👇 www.bbc.com/travel/artic...
bbc.com
10 winning photos from the World Food Photography Awards 2026
From a Soviet-era sanatorium to a floating market in Bangladesh, this year's World Food Photography Awards capture the many ways food shapes daily life around the world.
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Thiago Carvalho @cyrilpedia.bsky.social · 30/05/2026
'Except, it appears, time and again when there have been wholesale attempts to substitute experience with genAI it never quite works out as planned. But by then the damage is done. The experts have been felled, taking their know-how with them.' @tirscienceblog.bsky.social
totalinternalreflectionblog.com
The Dunning-Kruger chainsaw massacre
Just over a year ago, I wrote about the “chainsaw massacre” being perpetrated by Elon Musk and his acolytes at DOGE. At the time, these were the most visible elements – the most visible outrages – …
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Jake Wright @bcnjake.bsky.social · 29/05/2026
Once again: German universities were the envy of the world before the Nazis rose to power and took an ideological wrecking ball to the entire enterprise. If you want to know how long it took for German universities to recover… they haven’t.
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