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Kaska Koltowska

@lymphaticslab.bsky.social
489 followers 184 following 6 posts

Group leader at Uppsala University, fascinated by developmental biology, vascular biology and cell states.

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Reposted by Kaska Koltowska
Philippe Batut @philippebatut.bsky.social · 10/09/2026
🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇
science.org
Noncoding transcription controls the developmental dynamics of long-range gene regulation
The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...
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Kaska Koltowska @lymphaticslab.bsky.social · 20/08/2026
Proud to share our new paper in EMBO Reports! 🧬 How does a cell "decide" to become lymphatic vs blood endothelium? Turns out it's not just which genes switch on — it's how the genome folds around them. 💥 link.springer.com/content/pdf/... #Lymphatics #Zebrafish #DevBio #VascularBiology #Genomics
The topologically associating domains (TADs) and chromatin accessibility of lymphatic endothelial cells diverge from those of blood endothelial cells. These differences underlie the activation of LEC-specific regulatory networks governing cell identity and involving genes linked to lymphatic disease.
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Ben Hogan @benjhogan.bsky.social · 09/06/2026
Just a few months to IVBM in Australia! Come down and enjoy great science, food, beaches, wine and company. Time to register now at ivbm2026.com
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Kaska Koltowska @lymphaticslab.bsky.social · 27/04/2026
Only 3 days left to submit your abstract! Don't miss out on the opportunity to present at this fantastic meeting! 😊 💥 🤩
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Kaska Koltowska @lymphaticslab.bsky.social · 17/04/2026
Abstract deadline — April 30 for the 5th Nordic DevBio Meeting, Uppsala, Sweden, August 2026. Time to submit! Wonderful line-up of speakers including keynotes Marcos Gonzalez Gaitan and Corinne Houart! www.swedbo.se/the-5th-nord... #DevBio #StemCells #Regeneration #Uppsala2026 @swedbo.bsky.social
swedbo.se
The 5th Nordic Meeting on Development, Stem Cells and Regeneration – A Markus Wallenberg symposium – Swedish Developmental Biology Organisation
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Reposted by Kaska Koltowska
Milena Petkova @milena-kp.bsky.social · 16/11/2025
It was a great pleasure to be a part of this new study from @halinlab.bsky.social focusing on the #Lymphatics in human skin!
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Zebrafish Rock! @zebrafishrock.bsky.social · 20/11/2025
#KnowYourZDM: In 2019, a 10-year-old patient w/ a life-threatening lymphatic disorder was losing hope. Zebrafish to the rescue! Scientists created zebrafish with the same gene mutation and found a melanoma drug that fixed the fish. Then, doctors used the same drug on the patient to save his life! 🧪
Zebrafish are an excellent model for studying the development and function of blood and lymphatic vessels. Research in zebrafish has even led to treatments for lymphatic disorders in people. This image, taken using a powerful microscope that uses lasers to illuminate the fish, shows blood vessels (magenta) and lymphatic vessels (green) in the eye and head of an anesthetized, 6-week-old, transgenic zebrafish.

Credit: Daniel Castranova, National Institute of Child Health and Human Development, NIH
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EVBO @evborg.bsky.social · 09/10/2025
us06web.zoom.us/meeting/regi...
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Knut and Alice Wallenberg Foundation @kawresearch.bsky.social · 25/09/2025
Kaska Koltowska @uu.se har identifierat unika DNA-sekvenser som aktiveras när lymfkärl bildas. Hon hoppas nu att hennes kommande forskning ska avslöja nya dolda hemligheter om hur lymfkärl bildas #forskning #medicin #lymfödem @lymphaticslab.bsky.social tinyurl.com/muap24vj
tinyurl.com
Utforskar lymfsystemets djupaste hemligheter | Knut och Alice Wallenbergs Stiftelse
Kaska Koltowska har identifierat unika DNA-sekvenser som aktiveras när lymfkärl bildas. Hon hoppas nu att hennes kommande forskning ska avslöja nya dolda hemligheter om hur lymfkärl bildas.
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Knut and Alice Wallenberg Foundation @kawresearch.bsky.social · 25/09/2025
Kaska Koltowska @uu.se has identified unique DNA sequences, enhancers, which are active in lymphatic vessels. She hopes that new research will reveal new hidden secrets of the lymphatic vessel formation #research #lymphedema #medicine @lymphaticslab.bsky.social tinyurl.com/yfk7ett5
tinyurl.com
Exploring the innermost secrets of the lymphatic system | Knut and Alice Wallenberg Foundation
Kaska Koltowska has identified unique DNA sequences, enhancers, which are active in lymphatic vessels. She hopes that new research will reveal new hidden secrets of the lymphatic vessel formation.
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Karolinska Institutet @ki.se · 18/08/2025
Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...
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Rui Benedito @ruibenedito.bsky.social · 26/06/2025
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
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Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 01/07/2025
I am honoured to be elected as a Member of EMBO and look forward to contributing to its mission and community!
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Nature Cardiovascular Research @natcardiovascres.nature.com · 15/07/2025
❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas...
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Reposted by Kaska Koltowska
Kevin Thiessen, PhD @kevinthiessen.bsky.social · 26/06/2025
After 7 years and a lot of memories, I've finally decided to retire Zebrafish Rock! on social media. I really want to say it was always positive but I've had a tumultuous experience with the account. Those that make the community more toxic continue to be promoted to positions of power. 1/4
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EVBO @evborg.bsky.social · 13/06/2025
#EVBOSeminarSeries Moderated by Joanna Kalucka. Speakers: Ralf Adams and Mariona Graupera. ⏰When: Wednesday, 18th June 2025, 3PM EU time (2PM UK). Place: online. See you there! For registration evbo.org
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Miguel Torres @miguel-torres-1963.bsky.social · 27/05/2025
Here we study the origin of the cardiac cell lineages in the mouse embryo. Separate but coordinated lineages independently specified at gastrulation generate the myocardium and endocardium. Credits: Miquel Sendra & coll: Jorge Dominguez, K. McDole and L. Guinard authors.elsevier.com/sd/article/S...
authors.elsevier.com
ScienceDirect.com | Science, health and medical journals, full text articles and books.
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Vascular Signaling and Sensing Lab @vascsensinglab.bsky.social · 24/04/2025
Welcome to Toulouse 🇫🇷 for the first #EuropeanLymphaticSymposium - we had a fantastic first day with exciting #lymphatic science by @karinayaniv.bsky.social @taijamakinenlab.bsky.social, Kathleen Caron and many others. european-lymphatic-symposium.com/program/
Hotel Dieu - conference site
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Ben Hogan @benjhogan.bsky.social · 21/03/2025
A group leader position is open at Peter Mac in Melbourne, Australia! Join us! Applications until May 5. 👇👇 www.nature.com/naturecareer...
nature.com
Group Leader - Melbourne (Suburb), Greater Melbourne (Inner) (AU) job with Peter MacCallum Cancer Centre | 12837590
Peter Mac is recruiting a Group Leader to increase the capacity and efficiency of our “discovery to translation” cancer research pipeline.
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Claudio Cantù @claudiocantu81.bsky.social · 08/04/2025
Online #DevBio seminar from @liu.se Save the date 👇 @swedbo.bsky.social 🕕 Wed April 23rd 12:30-13:30 (CET) Assoc Prof @ppagella86.bsky.social on Oral Tissues & Disease Models & Prof. Neil Lagali on PAX6 and eye development Link: liu-se.zoom.us/j/6577579032... Passcode is given upon request!
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Journal of Experimental Medicine @jem.org · 08/04/2025
See a short video summary of the study by @zebrafish007.bsky.social: youtu.be/jEChI8XE_0g
youtu.be
The axillary lymphoid organ is an external, experimentally accessible immune organ in the zebrafish
Original paper: https://rupress.org/jem/article/222/6/e20241435/277359/The-axillary-lymphoid-organ-is-an-externalVideo summary by Daniel Castranova (Eunice K...
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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 07/04/2025
The heart's system of lymphatic vessels develop in the epicardium initiated by signalling of VEGFC & D 📷 Ester de la Cruz et al @miguel-torres-1963.bsky.social CNIC Madrid in @emboreports.org ➡️ bpod.org.uk/archive/2025...
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Ulvmar lab @ulvmarlab.bsky.social · 06/04/2025
Excellent opportunity for researchers within 7 years from PhD 👋 for a six-year career-development position! 🍀Establish your research group at Uppsala University - inflammation in cancer, in chronic inflammatory diseases or autoimmunity - vessels - immune cells - tissue uu.varbi.com/en/what:job/...
uu.varbi.com
Associate Senior Lecturer (SciLifeLab Fellow) in inflammation research
The Science for Life Laboratory (SciLifeLab) is a national center for leading edge technological infrastructures that supports large-scale data and hypothesis-driven research in the field of molecular
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Reposted by Kaska Koltowska
Olov Andersson @o-andersson-lab.bsky.social · 04/04/2025
Great opportunity & startup for someone that wants to start their lab studying inflammation/immune system (perhaps in metabolism, diabetes or the islet...) external/international candidates are wanted: uu.varbi.com/en/what:job/...
uu.varbi.com
Associate Senior Lecturer (SciLifeLab Fellow) in inflammation research
The Science for Life Laboratory (SciLifeLab) is a national center for leading edge technological infrastructures that supports large-scale data and hypothesis-driven research in the field of molecular
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Reposted by Kaska Koltowska
Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 20/03/2025
www.youtube.com/watch?v=seh5...
youtube.com
Why humans have puzzle-shaped cells
YouTube video by nature video
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Reposted by Kaska Koltowska
Makinen lab - Lymphatic Biology and Pathology @taijamakinenlab.bsky.social · 20/03/2025
If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape, check out our paper @Nature rdcu.be/eejhZ
rdcu.be
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
Nature - Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result...
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EVBO @evborg.bsky.social · 26/02/2025
Did you book? Places are filling up! Registration NOW OPEN - EVBO Summer School! 10-11 June 2025 | Biomedicum Helsinki, Finland The summer school will be preceded by the excellent and free-of-charge Wihuri Research Symposium on Cardiovascular Biology! More info here: buff.ly/42I9fvY
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Kaska Koltowska @lymphaticslab.bsky.social · 10/02/2025
🤩 Excited to share our protocol for computationally averaging confocal images of zebrafish lymphatic vessels to identify phenotypes! 🐟🔬 Check it out in Star Protocols 👉 star-protocols.cell.com/protocols/4030 #Zebrafish #Microscopy #StarProtocols
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Miikka Vikkula @mvikkula.bsky.social · 06/02/2025
International Conference on Vascular Anomalies: Translating basic research into new therapies (VAC 2025)! : lnkd.in/e6_BbzQF. Don't miss the event. The congress networking dinner nearly sold out! A few seats left for congress participation. lnkd.in/dzTfFVej #VASCAPA #HEVAS #CMTC #EVBO #ISSVA
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SFB 1348 @sfb1348.bsky.social · 17/01/2025
We have an exciting line-up of speakers for our @sfb1348.bsky.social meeting "Cellular Interfaces across Scales: from Molecules to Tissue Dynamics" from May 7 - 9, 2025. Registration will start on February 1, 2025. More information: crc1348-conference.ycode.site
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EVBO @evborg.bsky.social · 09/12/2024
This is the new official account of the European Vascular Biology Organisation. We are looking forward to connect to the #VascularBiology community! Follow us for bi-weekly seminars and scientific initiatives in support of the vascular biology community.
media.tenor.com
a woman wearing glasses says " follow me " while holding a pink object
ALT: a woman wearing glasses says " follow me " while holding a pink object
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Development @dev-journal.bsky.social · 30/11/2024
Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration Read this Research Article by Sierra Duca, Yu Xia, Michael R. M. Harrison, Jingli Cao and colleagues: buff.ly/49hhwIf
Figure 1 (A) Larval expression of vegfc:EGFP (green) and kdrl:DsRed (magenta) lines in a 2 dpf live fish. Scale bar: 200 µm. (B) Confocal images showing vegfc:EGFP (green) and kdrl:DsRed (magenta) expression in the trunk at 2 dpf. A single-channel image of vegfc:EGFP expression is shown in grayscale on the right. Scale bar: 100 µm. (C,D) Whole-mount images (maximum projections of z-stacks) of the ventricular surface showing expression of vegfc:EGFP (green) and flt1:tdTomato (magenta) at 5 wpf (C) or 8-9 wpf (D). Single-channel images of vegfc:EGFP expression are shown in grayscale on the right. The framed regions are enlarged beneath. The arrows indicate EGFP+tdTpmato+ arteries. Scale bars: 100 µm.
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