An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.

Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis-regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal tissue.

Updated: September 22, 2026Welcome to Masters of Microscopy: The People Behind the Lens, where we showcase and celebrate the individuals at the heart of the Nikon Small World competitions. They are sc...

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Many prokaryotes are diderms. They divide using an FtsZ division ring to simultaneously constrict physically coupled inner and outer membranes to form daughter cells with two membranes. Currently, onl...

The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...

Fischer et al. uncover a fundamental mechanism of membrane fusion during nuclear pore complex (NPC) assembly. Brl1 and Brr6 form ring-shaped, membrane-remodeling complexes that interact and bridge the nuclear envelope at NPC-assembly sites to mediate fusion. This pathway is conserved in humans via the metazoan fusogen CLCC1.

How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non-funct...

Metabolism is the reaction network that converts inanimate matter into living cells. There is no life without it. The network of approximately 400 enzymatic reactions that synthesize amino acids, nucl...

High-resolution maps and models of the bacterial ribosome provide new chemical insights into protein synthesis, and should enable the development of robust tools for cryo-EM structure modeling and ref...

“Such a radical shakeup in learning has never happened before, as far as I know. Is there even a way to learn about whether or not something has happened bef...

Abstract. Biases in molecular evolution can significantly influence evolutionary trajectories. They have been described in a variety of contexts, such as d

New study is among the first to quantify and explain slavery’s influence in contemporary U.S. health disparities

Using in situ cryo-electron tomography, researchers found a unique ‘arm’ domain on the small subunit of Chlamydomonas chlororibosomes. This discovery suggests that chlororibosome structure is more evo...

By combining biochemical assays and electron cryo-microscopy, Zhan, Abril-Garrido, et al. elucidated key steps of transcription initiation and the transition to elongation in the presence of the +1 nucleosome. The authors demonstrated for the first time that the +1 nucleosome has an active role in the initiation-elongation transition.

Nature Reviews Genetics - Genetic variation influences biological processes across scales; however, deciphering how effects propagate from molecules to whole organisms remains a key challenge in...

More than 80% of street space in Toronto is inequitably dedicated to motor vehicles. How can this be fairly re-designed?

Elimination of all spliceosomal introns reveals a spliceosome-independent eukaryote.

Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein synt...

Enhancers activate specific target promoters, but whether intrinsic enhancer-promoter compatibility contributes to this specificity is debated. Recent studies using different reporter assays have reac...

Science turned a serendipitous finding about lizard venom into one of the most important drugs of the century, but that type of research is getting harder to do.

Jeff Coller, a pioneering RNA biologist, has spent the past year vehemently advocating for the lifesaving promise of research in the face of federal cuts

By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University