Reposted by Petter BrodinThe Francis Crick Institute @crick.ac.uk · 28/05/20261/2 Meet the panellists for the first two recordings of season two of our podcast, A Question of Science. Book your tickets now to be part of the live studio audience at the recordings on 17 June, live at the Crick: lostintv.com/tv-show?id=1... 171
Reposted by Petter BrodinJournal of Human Immunity @jhumimmunity.org · 11/05/2026Thymic output in human newborns is shaped by environmental exposures and a common TCRD genetic variant. New study from Ziyang Tan, Camille Kergaravat, Antoine Toubert @upcite.bsky.social, Petter Brodin @petterbrodin.bsky.social @ki.se and colleagues: rupress.org/jhi/article/... 093
Reposted by Petter BrodinCasanova Lab @casanovalab.bsky.social · 05/05/2026New, fascinating insights into thymic output in young infants: Thymic output in human newborns is shaped by environmental exposures and a common TCRD genetic variant rupress.org/jhi/article/...rupress.orgThymic output in human newborns is shaped by environmental exposures and a common TCRD genetic variantLongitudinal profiling of 136 newborns shows thymic output peaks at 3–4 mo, correlating with plasma RANKL, lymphotoxin-α, and the TCRD variant rs2204985. I 031
Petter Brodin @petterbrodin.bsky.social · 23/02/2026New paper📢 - how many individuals are affected by an autoimmune disease. Together with epidemiology experts jonas Ludvigsson @ki.se we use 🇸🇪 population registry and find that 1/13 adults and 1/67 children are affected by autoimmunity: link.springer.com/article/10.1...link.springer.comIncidence and prevalence of autoimmune disease in the Swedish National Patient Register - European Journal of EpidemiologyEuropean Journal of Epidemiology - Standardized definitions of autoimmune disease (AD) are lacking. Therefore, we aim to propose a definition of AD for register-based research and estimate the... 090
Reposted by Petter BrodinJournal of Human Immunity @jhumimmunity.org · 20/02/2026Expanding the scope of human immunology in the Journal of Human Immunity. New Editorial from Petter Brodin @petterbrodin.bsky.social, Megan Cooper @macattacklab.bsky.social, Jean-Laurent Casanova @casanovalab.bsky.social, and colleagues in the JHI Editorial team:rupress.orgExpanding the scope of human immunology in the Journal of Human ImmunityA broader scope for the Journal of Human Immunity. 0126
Reposted by Petter BrodinAdrian Liston @labliston.bsky.social · 16/02/2026Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field www.annualreviews.org/content/jour...annualreviews.orgTissue Regulatory T CellsFOXP3+ regulatory T cells (Tregs) have well-defined roles in limiting systemic immune responses against diverse stimuli. However, the observation that a subset of Tregs also enter nonlymphoid tissues,... 14614
Petter Brodin @petterbrodin.bsky.social · 16/02/2026Paper alert 📢: What drives variation in humoral responses to viruses? collab with @etienne-patin.bsky.social @darraghduffy.bsky.social @lquintanamurci.bsky.social we show that for ~98k viral epitopes immunodominance vary by genetics, sex and origin: www.nature.com/articles/s41... 02710
Reposted by Petter BrodinJournal of Human Immunity @jhumimmunity.org · 13/02/2026Expanding the scope of human immunology in the JHI. In this Editorial, @petterbrodin.bsky.social, @macattacklab.bsky.social, @casanovalab.bsky.social, alongside JHI's Associate, Consulting, as well as Society Editors, outline a broader scope for the journal. rupress.org/jhi/article/...rupress.orgExpanding the scope of human immunology in the Journal of Human ImmunityA broader scope for the Journal of Human Immunity. 1106
Reposted by Petter BrodinLab on a Chip @labonachip.rsc.org · 05/01/2026Available to read now via #OpenAccess pubs.rsc.org/en/content/a... @ki.se @petterbrodin.bsky.socialpubs.rsc.orgGut health monitoring via intestinal barrier function screening using a transepidermal microneedle-based sensorThe growing prevalence of chronic digestive disorders, such as inflammatory bowel disease, underscores the urgent need for innovative solutions that enable longitudinal monitoring of disease progressi... 032
Reposted by Petter Brodinvalebodi.bsky.social @valebodi.bsky.social · 02/01/2026Gut health monitoring via intestinal barrier function screening using a transepidermal microneedle-based sensor (2026) Nicolas Maïno, Sihui Xuad, Petter Brodin and Onur Parlak @petterbrodin.bsky.socialpubs.rsc.orgGut health monitoring via intestinal barrier function screening using a transepidermal microneedle-based sensor - Lab on a Chip (RSC Publishing) DOI:10.1039/D5LC01004G 041
Reposted by Petter BrodinMRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 31/12/2025🎉Congratulations to @wiebkearlt.bsky.social, @petterbrodin.bsky.social and @borislenhard.bsky.social for being named on Clarivate's list of Highly Cited Researchers for 2025! This list celebrates influential academics whose work has made a profound impact on their field!lms.mrc.ac.ukThree LMS researchers named among most influential in the world in 2025Professors Wiebke Arlt, Petter Brodin and Boris Lenhard, who lead groups at the MRC Laboratory of Medical Sciences (LMS), have been included on the prestigious Highly Cited Researchers 2025 list. 0113
Petter Brodin @petterbrodin.bsky.social · 04/12/2025Me and a few leading colleagues discuss female-specific immune systems in health and disease. By @starrevartan.bsky.social in @newscientist.com www.newscientist.com/article/2501...newscientist.comWomen have supercharged immune systems and we now know whyBeing born with two X chromosomes brings a host of health benefits, and recognising this could lead to personalised medical treatments for men and women 2236
Reposted by Petter BrodinTRAstonDrs @castltrastondrs.medsky.network · 09/11/2025Recap 2023 via @petterbrodin.bsky.social @theguardian.com www.theguardian.com/science/2023... The term “immunity debt” was first introduced by French researchers in 2021. It refers to a population-wide effect rather than an individual-level one.theguardian.comImmunity debt: does it really exist?Some claim the rise in winter infections has been caused by the reduction of seasonal bugs during lockdowns. But experts are sceptical about these oversimplified explanations 151
Reposted by Petter BrodinKnut and Alice Wallenberg Foundation @kawresearch.bsky.social · 15/10/2025Why are more and more people suffering from #allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns @petterbrodin.bsky.social @ki.se has developed a technique to map #immunesystem development from a single drop of blood. tinyurl.com/3j22dyw8tinyurl.comHow the immune system develops in newborn babies | Knut and Alice Wallenberg FoundationWhy are more and more people suffering from allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns. Wallenberg Scholar Petter Brodin has developed a ... 093
Reposted by Petter BrodinRockefeller University Press @rupress.org · 24/10/2025In new review @jhumimmunity.org, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/... 111
Reposted by Petter BrodinJournal of Human Immunity @jhumimmunity.org · 31/10/2025The seven enigmas of #SARSCoV2: From the past to the future. New review from Evangelos Andreakos, Helen Su, Jean-Laurent Casanova (@casanovalab.bsky.social) and colleagues: rupress.org/jhi/article/... #InbornErrorsOfImmunity #InfectiousDiseases #PopulationGenetics 164
Petter Brodin @petterbrodin.bsky.social · 22/09/2025The American Association of Immunologists AAI meeting will be in Boston, April 15-19, 2026. Come join me and @chrysothemisbrown.bsky.social at this exciting Symposium on Early life immune development. Submit your abstracts by October 15th! immunology2026.aai.org/session/earl...immunology2026.aai.orgEarly Life Immune Development and Function - IMMUNOLOGY2026™Time: 8:00 - 11:30 AM Chairs: Chrysothemis C. Brown, Memorial Sloan Kettering Cancer Ctr., USA Petter Brodin, Imperial Col. London and Karolinska Inst., GBR, SWE 0133
Reposted by Petter BrodinTRAstonDrs @castltrastondrs.medsky.network · 10/09/2025#Medsky🧪 #IDsky #immunosky #publichealth @petterbrodin.bsky.social , @casanovalab.bsky.social et al To determine the underlying genetic causes & other modifying factors like sex hormones , interferon responses impacting restrained #Tcell responses to #SARSCoV2 & #viralpersistence in #LongCOVID. 173
Petter Brodin @petterbrodin.bsky.social · 25/08/2025Thx for highlighting @sun-in-winter12.bsky.social 292
Reposted by Petter Brodinvalebodi.bsky.social @valebodi.bsky.social · 07/08/2025Variation in the human immune system is largely driven by non-heritable influences @petterbrodin.bsky.social P. Brodin et al. Cell. 2015.pubmed.ncbi.nlm.nih.govVariation in the human immune system is largely driven by non-heritable influences - PubMedThere is considerable heterogeneity in immunological parameters between individuals, but its sources are largely unknown. To assess the relative contribution of heritable versus non-heritable factors,... 161
Petter Brodin @petterbrodin.bsky.social · 11/07/2025Weight loss improves health but What happens to cells in the fat during weight loss? Intriguingly, immune cell numbers decrease but their activated states persist w chronic inflammatory potential. Beautiful work from neighbors @mrc-lms.bsky.social Will Scott et al www.nature.com/articles/s41...nature.comSelective remodelling of the adipose niche in obesity and weight loss - NatureAn atlas study of adipose tissue in people with obesity undergoing weight loss and their lean counterparts reveals that weight loss reduces cell senescence but cannot reverse all the metabolic problem... 15513
Petter Brodin @petterbrodin.bsky.social · 25/06/2025New paper 📣! Pixelgen reports its incredible new Proximity Network Assay (PNA)->3D maps of 155 proteins in single cells by sequencing by barcoded antibodies and in situ rolling circle amplification yields >40,000 spatial nodes/cell: www.biorxiv.org/content/10.1... 1146
Petter Brodin @petterbrodin.bsky.social · 25/06/2025No evidence for neutralizing IL1RN autoantibodies in our cohorts of MIS-C, SARS-CoV2 pneumonia or vaccine-induced myocarditis. onlinelibrary.wiley.com/doi/10.1111/... Great work by Anish Behere in Nils Landegren lab, Uppsala universityonlinelibrary.wiley.comEvaluating IL1RA‐Autoantibodies Across SARS‐CoV‐2‐Related DiseasesClick on the article title to read more. 0185
Petter Brodin @petterbrodin.bsky.social · 23/06/2025Exciting new cell state model from @arcinstitute.org 010
Petter Brodin @petterbrodin.bsky.social · 27/05/2025Absolute pleasure to be teaching human systems immunology @efis-immunology.bsky.social summer school in beautiful Alghero, Sardinia. 3274
Reposted by Petter BrodinLong Covid Kids @longcovidkids.bsky.social · 23/05/2025"Children should be included in ongoing and future clinical trials for Long Covid Age-related protections & regulations must be incorporated, including obtaining institutional review board/research ethics approval along with paediatric assent & parental publications.ersnet.org/content/erj/... 13212
Reposted by Petter BrodinJosh Waterfall @joshwaterfall.bsky.social · 30/04/2025Reminder to join us June 5/6 in Paris if you're interested in pediatric immunity and cancer development ! @institutcurie.bsky.social @gustaveroussy.fr @hopitalnecker.bsky.social @institutimagine.bsky.social 1102
Reposted by Petter BrodinRockefeller University Press @rupress.org · 23/04/2025New in @jumimmunity.org: Human #InbornErrorsOfImmunity: 2024 update on the classification from the @iuis-online.bsky.social Expert Committee: rupress.org/jhi/article/... See also the accompanying diagnostic guide by Bousfiha et al.: rupress.org/jhi/article/... 042
Petter Brodin @petterbrodin.bsky.social · 15/04/2025Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee url:https://rupress.org/jhi/article/1/1/e20250003/277390/Human-inborn-errors-of-immunity-2024-update-on-the 0196
Reposted by Petter BrodinMilieu Intérieur Consortium @milieuinterieur.bsky.social · 03/04/2025Amazing study showing protective effect of herpes zoster vaccination against dementia with interesting sex differences @sexdiffimmunity.bsky.social #vaccines work! #immunosky #medsky 0124
Reposted by Petter BrodinUCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 28/03/2025Co-senior author from this study Prof Coziana Ciurtin will be talking alongside @petterbrodin.bsky.social in a RITA webinar on Sex Biases on Autoimmunity next Tuesday - should be a great discussion. Register 👇 #ImmunoSky #sexdifferences register.gotowebinar.com/register/822...register.gotowebinar.com 0229
Reposted by Petter BrodinLong Covid UK @longcoviduk.bsky.social · 10/03/2025🔥1/3. Next in the Fireside Chat series from The #LongCovid Clinic - What You CAN Do! ‘Covid & the Immune System’ 🗓️ Wednesday 12th March 2025 at 6pm GMT @binitakane.bsky.social & @helenoakleigh.bsky.social are joined by Consultant Immunologist @petterbrodin.bsky.social! Link ⬇️ 23819
Reposted by Petter BrodinTRAstonDrs @castltrastondrs.medsky.network · 09/03/2025#Medsky🧪#oncosky #pedsky @petterbrodin.bsky.social et al . A systems-level analysis of immune responses in 191 children within a population-based cohort with diverse tumors & reveal that age & tumor type shape immune responses differently.#immunotherapies for childhood cancer. 131
Reposted by Petter BrodinGustavo Monasterio Ocares @gamonasterioo.bsky.social · 07/03/2025How do immune responses vary across different childhood ages and tumor types? A crucial study from @petterbrodin.bsky.social’s lab freshly baked on #SystemsImmunology, advancing precision medicine in pediatric diseases! www.cell.com/cell/fulltex...cell.comSystems-level immunomonitoring in children with solid tumors to enable precision medicineIn a population-based cohort of 191 children with diverse solid tumors, systems-level analyses unravel immune variation with age and tumor type and provide a reference for future precision immunothera... 053
Reposted by Petter BrodinProf John Gordon @profcelentyx.bsky.social · 06/03/2025#Paediatrics | #Cancer | #ImmuneSystem | #Immunotherapy | Yet Another Phenomenal Resource from @petterbrodin.bsky.social & Friends | Breaking OPEN ACCESS Study Online at @cellpress.bsky.social | #immunogenicity | #Tcells | #inflammation |cell.comSystems-level immunomonitoring in children with solid tumors to enable precision medicineIn a population-based cohort of 191 children with diverse solid tumors, systems-level analyses unravel immune variation with age and tumor type and provide a reference for future precision immunothera... 031
Reposted by Petter BrodinJosh Waterfall @joshwaterfall.bsky.social · 05/03/2025Interested in the relationship between the developing immune system and pediatric cancer ? Come join us for the first Paris Kids Cancer symposium June 5/6 institut-curie.org/symposium-pa... @institutcurie.bsky.social @aphp.bsky.social @gustaveroussy.fr @institutimagine.bsky.socialinstitut-curie.orgSymposium Paris Kids Cancer 2025 - Institut CurieFind Symposium Paris Kids Cancer 2025. The Institut Curie is the leading center for research and the fight against cancer in France. 272
Reposted by Petter BrodinJosh Waterfall @joshwaterfall.bsky.social · 05/03/2025Great #immuno speakers including @belkaidlab.bsky.social @petterbrodin.bsky.social @florentginhoux.bsky.social Arndt Borkhardt, Melanie Conrad, Sonia Garel, Sylvain Latour, Johnny Ludvigsson, Bernard Malissen, Mihai Netea, Anindita Roy and Chenqu Suo 021
Reposted by Petter BrodinSeth Thomas Scanlon @immunoeditor.bsky.social · 28/02/2025To commemorate #RareDiseaseDay, here are some recent #Science #Immunology research papers that elucidate the immune mechanisms underlying certain rare human diseases and/or report new strategies to treat them! @science.org 14514
Reposted by Petter BrodinBogunovic Lab @bogunoviclab.bsky.social · 26/02/2025It’s approaching. Join us in person. Henry Kunkel Society Meeting on "Genes & Immunity" and join us in Belgrade from April 10-12, 2025. henrykunkelsociety.org/meetings/ #HKS2025 #Immunology 🧬🔬 0116
Petter Brodin @petterbrodin.bsky.social · 26/02/2025Early in life, secondary bile acids are generated by colonizing microbes, associated with risks of immune-mediated diseases and act as immunomodulatory substances. Great collaborative study now online! 0217
Reposted by Petter BrodinMann Lab @mannlab.bsky.social · 19/02/2025Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️nature.comPlasma proteome variation and its genetic determinants in children and adolescents - Nature GeneticsThis mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics. 15125
Petter Brodin @petterbrodin.bsky.social · 20/02/2025Thanks for inviting me to this lovely meeting in beautiful Lorne, Australia 070
Reposted by Petter BrodinMichael Peluso, MD @michaelpelusomd.bsky.social · 16/02/2025Nice op-ed from @polybiorf.bsky.social on the need for more Long COVID trials. 02712
Reposted by Petter BrodinTcellogic (Sue Kaech) @tcellogic.bsky.social · 15/02/2025news.aai.org/2025/02/15/s...news.aai.orgStatement on Threat to the Federal Scientific Workforce - AAI NewsAA is deeply concerned about the damage to the biomedical research enterprise that will occur as a result of drastic reductions in the size of the federal scientific workforce 074
Reposted by Petter BrodinPutrino Lab @putrinolab.bsky.social · 11/02/2025Honored to be a part of the work led by @polybioRF and @microbeminded2 published in @TheLancetInfDis discussing actionable strategies to adequately address SARS-CoV-2 persistence in #LongCovid. This paper covers discourse on how to look for and measure severity of persistence 1/ 26311
Reposted by Petter BrodinLucasbouys @lucasbouys.bsky.social · 12/02/2025Looking for your next move as a clinician-scientist? 3 positions of Transition to Independence Fellow for 3 years in @mrc-lms.bsky.social @imperialcollegeldn.bsky.social 80% protected research time + 20% clinics in an amazing scientific environment in London 👩🏻⚕️👨🏻⚕️👩🏻🔬👨🏻🔬 🧫🔬deadline 4th March! DM me for infoimperial.ac.ukDescriptionPlease note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment... 154