Who doesn't want cancer testing results at lower cost, with greater speed and accuracy? Interdisciplinary innovators like Cancer Center at Illinois (CCIL) program leader Brian Cunningham are among the pioneers of the emerging field of point-of-care (POC) diagnostic technology aiming to make this dream a reality.

Microplastics and nanoplastics are ubiquitous environmental contaminants, with growing evidence of their ecological and human health risks. However, a clear understanding of their impacts remains…

Microfluidic devices enable high-throughput sample processing with remarkable parallelization and miniaturization. While fluorescence microscopy provides a convenient method for reading out signal fro...

Detection of parasite biomarkers is critical for diagnosis and treatment monitoring; however, proper analysis of whole blood samples typically requires red blood cell lysis. While lysis is easily achi...

Cellular state, function, and disease all contribute to whole-cell mechanical properties. Investigating these relationships is often difficult due to low measurement throughput, inability to draw one-...

Emerging therapies in sickle cell disease (SCD) aim to restore healthy red blood cell (RBC) function, but they often yield heterogeneous cellular responses. There are no proven techniques to evaluate ...

Electroporation (EP) is one of the leading non-viral intracellular delivery methods used in various applications across research and cell therapy development and manufacturing. Currently widely used b...

The limited predictive power of animal models remains a major bottleneck in drug development, particularly in assessing drug-induced liver injury (DILI). To address this, we developed a novel in vitro...

Automating the isolation of rare cells such as circulating tumour cells (CTCs) within crowded microfluidic environments remains a bottleneck in liquid biopsy workflows. Optical tweezers offer contact-...

Researchers from Brown University and their collaborators have developed a new way to measure the properties of cells—an important development, they say, because accurate measurements of changes in cell elasticity can be used to better understand diseases, diagnose patient symptoms and provide more accurate prognoses.