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Lili Niu

@liliniu.bsky.social
82 followers 118 following 14 posts

Interested in proteomics technologies, pQTLs, proteome variation in health and diseases. Views are my own.

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Reposted by Lili Niu
Mann Lab @mannlab.bsky.social · 13/11/2025
Fantastic time at #HUPO2025 in Toronto! Congratulations to our talented Early Career researchers! Proud winners: Oeller Marc Oeller🥇 1st Place Poster, Kathrin Korff 🥈 Runner-up Poster, and @carolineweiss.bsky.social 🎤 3-Minute Thesis award! The future of #proteomics research is bright!
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Reposted by Lili Niu
Evosep @evosep.bsky.social · 04/11/2025
Scaling plasma proteomics to 6400 patients? Hear Lili Niu at our #HUPO2025 breakfast on how 1152 samples/day and a 200 SPD Evosep Eno + Orbitrap Astral workflow quantified >400 proteins per sample. Register: www.evosep.com/hupo2025/
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Lili Niu @liliniu.bsky.social · 08/11/2025
This #hupo2025 marks the first HUPO since I became a group leader last month at Shenzhen Bay Laboratory in Shenzhen, China. I will be presenting a talk and a poster👇 Looking very much forward to connecting with old friends and meeting new ones!
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Reposted by Lili Niu
Mann Lab @mannlab.bsky.social · 07/11/2025
If you are at HUPO 2025, catch up with our team @mannlab.bsky.social to hear about our exciting work in single-cell proteomics, immunopeptidomics, spatial proteomics, and the latest advances in mass spectrometry technology!
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Reposted by Lili Niu
Max Planck Institute of Biochemistry @mpibiochem.bsky.social · 01/07/2025
🎉 Congratulations to Matthias Mann on 20 years leading Proteomics & Signal Transduction at MPI of Biochemistry! Two decades of groundbreaking mass spectrometry research and training excellent future scientists. #MS #Proteomics #Science @mannlab.bsky.social
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Reposted by Lili Niu
Kevin Drew @ksdrew.bsky.social · 30/05/2025
Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....
embopress.org
hu.MAP3.0: atlas of human protein complexes by integration of >25,000 proteomic experiments | Molecular Systems Biology
imageimagehu.MAP3.0 integrates mass spectrometry experiments to identify human protein complexes. Using this resource, this study characterizes covariation of complexes, identifies mutually exclusive ...
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Reposted by Lili Niu
MS Bioworks @msbioworks.bsky.social · 19/02/2025
New from @mannlab.bsky.social Champions of Europe! 1200+ proteins from plasma. More of this please. bsky.app/profile/mann...
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Reposted by Lili Niu
Bini Ramachandran @itsbinir.bsky.social · 19/02/2025
Neat plasma from yielding 1200+ proteins from a >3000 samples study is phenomenal.. Even more phenomenal is demonstrating the feasibility of linear comparisons across samples acquired over 2.5 months of instrument time.. Awesome..
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Reposted by Lili Niu
Mann Lab @mannlab.bsky.social · 19/02/2025
Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️
nature.com
Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics
This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.
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Reposted by Lili Niu
bioRxiv SysBio @biorxiv-sysbio.bsky.social · 10/02/2025
A perturbation proteomics-based foundation model for virtual cell construction www.biorxiv.org/content/10.1101/202…
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Reposted by Lili Niu
Daniel 🕹️ @strengejacke.de · 06/01/2025
Not every analysis of multiple (<whatever>) requires multiplicity adjustments (correcting p-values for multiple testing): www.sciencedirect.com/science/arti...
sciencedirect.com
Inconsistent multiple testing corrections: The fallacy of using family-based error rates to make inferences about individual hypotheses
During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint uni…
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Reposted by Lili Niu
Nature @nature.com · 23/01/2025
A Chinese-built large language model called DeepSeek-R1 is thrilling scientists as an affordable and open rival to ‘reasoning’ models such as OpenAI’s o1 go.nature.com/3WroTb1
go.nature.com
China’s cheap, open AI model DeepSeek thrills scientists
DeepSeek-R1 performs reasoning tasks at the same level as OpenAI’s o1 — and is open for researchers to examine.
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Reposted by Lili Niu
Nick Morrice @pommie331.bsky.social · 14/01/2025
Nice review of plasma proteomics methods by Josh Coon and his group . However the perchloric acid treatment of plasma will lead to the formation of cysteic acid and methionine sulphone which is not mentioned for the DIA search. .https://www.biorxiv.org/content/10.1101/2025.01.08.632035v1
biorxiv.org
A Technical Evaluation of Plasma Proteomics Technologies
Plasma proteomic technologies are rapidly evolving and of critical importance to the field of biomedical research. Here we report a technical evaluation of six notable plasma proteomic technologies - ...
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