Reposted by Sheila I. Jensen
Fungal natural products Heterologous production: fast, easy, cheap.
Introducing BLACK YEASTS 🍄
Fast to engineer, capable of expressing complex fungal biosynthetic pathways, and ready to accelerate natural product discovery.
Check the paper 🧪
www.nature.com/articles/s41...
#SyntheticBiology #fung
nature.com
Black yeasts are efficient heterologous hosts for the production of a wide range of fungal polyketides - Nature Chemical Biology
Here, the authors establish and validate two black yeasts as heterologous hosts for fungal polyketide discovery and production, combining the metabolic robustness of filamentous Aspergillus species wi...