Expectations can inform fast, accurate decisions. But what informs expectations? Here we test the hypothesis that expectations are set by dynamic inference from memory. Participants performed a cue-gu...

Neuropsychopharmacology - Robust changes in brain function require high D2 receptor occupancy by prochlorperazine: an imaging correlate for the antipsychotic therapeutic window

Neuropsychopharmacology - Comparing brain absorption and lung deposition of nicotine salts and free-base e-cigarettes: insights from [11C]nicotine PET imaging

xenium_NAC. Contribute to LieberInstitute/xenium_NAC development by creating an account on GitHub.

Neuropsychopharmacology - Development of a nose-poke restricted vaporized cocaine self-administration model in mice

This is a Perspective covering a Python toolbox for neuroscience research that enables users to fetch datasets, construct networks and null models, estimate graph metrics, fit statistical models and v...

While social interactions and actively chosen solitude both contribute to well-being, existing measures focus solely on one dimension. We developed the SOcial experiences' daiLy Occurrence (SOLO) sca...

Neuropsychopharmacology - Chronic ethanol self-administration alters dopamine in the caudate nucleus and putamen of rhesus macaques in a sex-dependent manner

Reward-predictive cues can influence decision-making and promote the pursuit of specific outcomes. This influence is classically studied using specific Pavlovian-to-instrumental transfer (sPIT), in wh...

Risk attitudes can shift across contexts and even between identical choices. Here, the authors show that as parietal payoff representations grow noisier, the brain leans more on prior beliefs, biasing...

Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...

Using a combined approach of monkey electrophysiology, artificial neural networks and human psychophysics, Xue et al. show that neuronal interference from irrelevant information underlies behavioral e...

“A month is crazy,” says one former recipient, referring to a new funding opportunity’s timeline.

The website of the 52nd EBBS Meeting :: EBBS 2027

Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption

Neuropsychopharmacology - Recent advances in individual differences in addiction neuroscience in animal models and clinical studies

Population-level brain patterns for new studies. Browse, explore, and download published neuromarkers.

Neuropsychopharmacology - Selective orexin receptor cross-over treatment increases resilience and expression of neuroplastic signaling genes

Schizophrenia, bipolar disorder, and major depression vary in their age of onset, cognitive impacts, degree of impairment, and clinical course. However, since psychosis is a transdiagnostic feature th...

Author summary Despite the complex wiring patterns found in the cortical connectome, many dynamical properties of macroscale cortical activity can be surprisingly well explained by treating the cortex...

Background Non-invasive modulation of deep brain structures remains a major challenge in human neuroscience and neurorehabilitation. Transcranial temporal interference stimulation (tTIS) has emerged a...

Neuropsychopharmacology - Early life stress induces sex-specific changes in cognitive and affective behavior associated with disrupted noradrenergic physiology

The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...

Abstract. Functional connectivity is frequently used to assess dynamic brain functioning and predict individual differences in behavioral outcomes, such as psychopathology. Inferences from functional ...

Semaglutide treatment for 3 months in female mice improved physiological function, attenuated hallmarks of ageing and modulated nutrient sensors and conserved genetic regulators of ageing.

Neuropsychopharmacology - Acute and post-acute neurobehavioral responses to lysergic acid diethylamide in healthy subjects: a randomized controlled study

Whether the heterogeneity of psychiatric conditions converges on shared neurophysiological alterations or translates into distinct signatures remains unclear. We assembled high-density electroencephal...