Sign in

Jobe Ritchie

@jobeneuro.bsky.social
30 followers 15 following 21 posts

Investigating the impact of substance abuse on brain function. Current post doc in the Kash Lab at UNC Chapel Hill. I use fiber photometry and machine learning in tandem with behavioral neuroscience approaches to study dopamine and serotonin circuitry.

PostsRepliesMedia
Reposted by Jobe Ritchie
Meghan Flanigan @meghanflanigan.bsky.social · 05/10/2026
New lab manager ad is live! Please share with trainees! jobrxiv.org/job/medical-...
jobrxiv.org
Laboratory Manager
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
011
Reposted by Jobe Ritchie
Julia Mitchell, PhD @juliamitchell.bsky.social · 30/09/2026
really very extremely excited (and proud!!) of my first postdoc paper officially out TODAY!! I’ve been investigating how simultaneous alcohol and nicotine exposure alter PL activity and anxiety-like behavior, and love the direction the work is taking us. www.sciencedirect.com/science/arti...
sciencedirect.com
Alcohol and nicotine vapor co-exposure differentially engages prelimbic prefrontal cortex activity and decreases anxiety-like behavior in rats
Alcohol and nicotine are two leading causes of preventable deaths in the United States. Simultaneous co-use of alcohol and nicotine is rising, as is t…
2136
Reposted by Jobe Ritchie
Meghan Flanigan @meghanflanigan.bsky.social · 29/09/2026
The Flanigan Lab at MUSC is looking for a new laboratory manager! If you're interested in stress, social behaviors, and/or serotonin, want to work in a scientific team, and are looking for a long-term lab position, this is the opportunity for you!
156
Reposted by Jobe Ritchie
Neuropsychopharmacology @npp-journal.bsky.social · 22/09/2026
#TWiNPP Ritchie et al. examine how binge alcohol drinking alters serotonin dynamics in the anterior cingulate cortex and central amygdala. Results highlight circuit-specific roles for serotonin in alcohol-related behaviors www.nature.com/articles/s41...
nature.com
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
041
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 15/09/2026
new paper out, led by @jobeneuro.bsky.social , exploring 5HT dynamics in cingulate and central amygdala, and how a history of alcohol consumption changes them! www.nature.com/articles/s41...
nature.com
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
46322
Jobe Ritchie @jobeneuro.bsky.social · 16/09/2026
Excited to share this data from the @superkash.bsky.social lab on the effects of binge alcohol drinking on serotonin signaling in central amygdala and cingulate cortex. We observed interesting sex-, stimulus modality-, and brain region-dependent effects of alcohol. www.nature.com/articles/s41...
nature.com
Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption - Neuropsychopharmacology
Neuropsychopharmacology - Selective dysregulation of serotonin dynamics in the anterior cingulate cortex and central amygdala following binge alcohol consumption
021
Reposted by Jobe Ritchie
Takuya Sasatani @takuyasasatani.bsky.social · 14/09/2026
Miniscope Zero, the first fully wireless Miniscope, is on @biorxivpreprint.bsky.social! Wireless power + data enable neural recordings in enclosed mazes, 3D environments & from two animals at once! @miniscope.bsky.social Paper: doi.org/10.64898/202... Wiki: miniscope.org/wiki/Minisco...
48934
Jobe Ritchie @jobeneuro.bsky.social · 04/09/2026
I wanted to create a behavior analysis pipeline that fit our workflow in an efficient and user friendly way. ABEL delivers on that goal for new and experienced users in Kash Lab and I hope others find it to be of benefit as well. Happy to answer any questions!
053
Reposted by Jobe Ritchie
Tallie Z Baram @talliezee.bsky.social · 06/05/2026
🧠🧪 join us here at the vibrant UC Irvine. Any career level. Great science, collaborative folks, and the weather is tolerable🤗. Please amplify @thebalelab.bsky.social @cate-cholamine.bsky.social @mayoonthebrain.bsky.social @karenswilcoxphd.bsky.social @acnporg.bsky.social @heydrdukes.bsky.social
0119
Reposted by Jobe Ritchie
Jae Young Choi @jychoi.bsky.social · 30/04/2026
I'm looking to hire a postdoc. Please share if you can!
04561
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 22/04/2026
Kash Lab April 2026
Black and White photo of a group of people smiling at a camera while lined up.yellowish photo of a group of people grumping at a camera while lined up.
3291
Jobe Ritchie @jobeneuro.bsky.social · 19/04/2026
Really nice pain work in vlPAG
000
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 26/03/2026
Our NIAAA funded Post-DoctT32 has received its NoA (non competing renewal). Are you looking for a post-doc and interested in joining our amazing center? If so, reach out! Here is a convenient form that you can use to upload CV and a cover letter! unc.az1.qualtrics.com/jfe/form/SV_...
27558
Reposted by Jobe Ritchie
Keri Martinowich @martinowk.bsky.social · 25/03/2026
Early for #FluorescenceFriday, but got an early peek in a project meeting - strucure is just so incredible - zoom in of tryptophan hydroxylase 2 labeling 🟣 of serotonin neurons in the dorsal raphe of human 🧠. Experiment and image credit to @ishbeldelrosario.bsky.social @svitlanabach.bsky.social
Single molecular fluorescence in situ hybridization to outline white matter tracts (green, labeling MBP) and serotonin neurons marked in purple with TPH2
14010
Jobe Ritchie @jobeneuro.bsky.social · 15/03/2026
Beautiful fluorescence imaging in human raphe. Love to see it!
052
Reposted by Jobe Ritchie
Research Society on Alcohol @rsaofficial.bsky.social · 20/02/2026
🎉 RSA Members in the news 📰 Tom Kash and Bob Messing contributed to this NYT article on how alcohol impacts the body 🔗https://nyti.ms/4kLkiLG
nyti.ms
What Alcohol Does to the Body
From the moment you take a sip, drinking starts to influence your biology. Here’s an inside look.
1119
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 13/02/2026
Nice article on how alcohol impacts your body. I spoke to author about alcohol and brain. www.nytimes.com/2026/02/12/w...
nytimes.com
What Alcohol Does to the Body
22510
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 13/02/2026
Nice work from my long time collaborator and pal Andrew Holmes' lab, led by the amazing Olena Bukalo. www.nature.com/articles/s41...
nature.com
Astrocytes enable amygdala neural representations supporting memory - Nature
Astrocytes in the basolateral amygdala dynamically track fear state and support fear memory retrieval and extinction.
04411
Reposted by Jobe Ritchie
Yttri Lab @yttrilab.bsky.social · 07/01/2026
Hot off the @nature.com press!! Our A-SOiD behavior library developed specifically for pain to quantify a new chemogenetic gene therapy that targets opioid circuit in ACC without addictive properties @flybottleescape.bsky.social @cmu-neuroscience.bsky.social @cmu.edu www.nature.com/articles/s41...
nature.com
Mimicking opioid analgesia in cortical pain circuits - Nature
The anterior cingulate cortex encodes affective pain behaviours modulated by opioids; targeting opioid-sensitive neurons through a new chemogenetic gene therapy replicates the analgesic effects of mor...
1208
Reposted by Jobe Ritchie
⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · 06/01/2026
✨New Corder Lab preprint 🧠⚡️ - from Dr Sophie Rogers ! Differential modulation of aversive signaling by expectation across the cingulate cortex We image the same ACC + RSC neurons over time during noxious fear learning to ask: who encodes aversion vs who predicts it 🔮 biorxiv.org/content/10.6...
1269
Reposted by Jobe Ritchie
Marija Kundakovic @kundakoviclab.bsky.social · 04/01/2026
Extremely excited & proud to share our new preprint - we provide for the first time a single cell map of the mouse brain across sex, the estrous cycle, and peripartum! Data are 🔥 👇 "Single-cell map of the female brain across reproductive transitions" www.biorxiv.org/content/10.6...
714062
Jobe Ritchie @jobeneuro.bsky.social · 02/01/2026
Teemo the Orange and Lily the Dilute Torti
150
Reposted by Jobe Ritchie
Bryan Roth @zenbrainest.bsky.social · 27/12/2025
Postdoctoral fellowship available in structure guided drug discovery in @RothLabUNC Please RT
01420
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 24/12/2025
Very cool paper from @jangrundemann.bsky.social lab! Axon initial segment dynamics during associative fear learning | Nature Neuroscience share.google/GH5iaWUINB5w...
share.google
Axon initial segment dynamics during associative fear learning - Nature Neuroscience
Benoit, Ganea et al. show that changes in axon initial segment (AIS) length in the prefrontal cortex of mice accompany fear learning and extinction, revealing AIS plasticity as a key feature of neuron...
1264
Jobe Ritchie @jobeneuro.bsky.social · 23/12/2025
This was a fun project with some surprising results along the way. Excited to have our recent 5HT work from the @superkash.bsky.social Lab out in preprint.
020
Jobe Ritchie @jobeneuro.bsky.social · 08/12/2025
Excited to publish my first alcohol paper and first paper as a post doc in the @superkash.bsky.social Lab, titled Lateral hypothalamus CRFR1 regulation of binge drinking: divergence along anterior-posterior axis. Available here authors.elsevier.com/c/1m84v_GtWa...
0115
Jobe Ritchie @jobeneuro.bsky.social · 16/09/2025
CRFR1 in lateral hypothalamus regulates binge alcohol drinking. Exciting location-specific effects along AP axis. Preprint available now. www.biorxiv.org/content/10.1...
biorxiv.org
Lateral hypothalamus CRFR1 regulation of chronic binge drinking: divergence along anterior-posterior axis
Binge alcohol drinking increases the risk of developing an alcohol use disorder (AUD) and comorbid psychopathology. The lateral hypothalamus (LH) is a brain structure that integrates cognitive and sen...
000
Jobe Ritchie @jobeneuro.bsky.social · 25/05/2025
Queen Lily #cats #dilutetorti
120
Jobe Ritchie @jobeneuro.bsky.social · 10/04/2025
Hot off the press! Sex-dependent role of the dorsolateral septum in shaping contextual cocaine memory strength. Spear headed by Shuyi Qi from the Fuchs Lab at WSU. @mergezettegerke.bsky.social doi.org/10.1016/j.ne...
doi.org
Redirecting
020
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 29/03/2025
oh hey, this paper is out now! Led by JR Haun, former Kash lab postdoc! pubmed.ncbi.nlm.nih.gov/40153436/
pubmed.ncbi.nlm.nih.gov
Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system - PubMed
High-intensity alcohol drinking during binge episodes contributes to the socioeconomic burden created by alcohol use disorders (AUDs), and nociceptin receptor (NOP) antagonists have emerged as a promi...
1307
Reposted by Jobe Ritchie
Tom Kash @superkash.bsky.social · 05/03/2025
Picture day for Kash Lab. Rain can't stop us.
A group of people pose, smiling, with their arms crossed in front of them. this group of people is the Kash Lab.
3444
Jobe Ritchie @jobeneuro.bsky.social · 27/02/2025
With some luck, I caught a plane and a bird in my sunrise pics this morning. #photography #sunrise #birds
0300
Reposted by Jobe Ritchie
Tallie Z Baram @talliezee.bsky.social · 31/12/2024
No, these arent tulips. The glorious shapes are basolateral amygdala CRH+ cells projecting to both BNST (green) & NAc (magenta). Dual projectors = white-hot. Wishing y'all a rewarding, chaos-free 2025 @superkash.bsky.social @martinowk.bsky.social @siegenthalerlab.bsky.social @cannabrain.bsky.social
flower-like structures are brain cells in the amygdala that send processes to two different brain regions, one shown in green the other in magenta. cells that collateralize to both are white
1485
Jobe Ritchie @jobeneuro.bsky.social · 01/12/2024
Had a wonderful first-time visit to Charlotte, NC. Beautiful city! Bechtler Museum of Modern Art was a treat. No pics from inside, but here is "The Firebird" by Niki de Sainte-Phalle #sculpture #Charlotte
The Firebird by Niki de Sainte-Phalle. Located at Bechtler Museum of Modern Art in Charlotte, NC.
030
Jobe Ritchie @jobeneuro.bsky.social · 29/11/2024
Thanksgiving cheesecake bake off results. #baking #cheesecake #desserts 1- Dark chocolate crust with tangy orange glaze 2- Maple glazed with salty candied pecans 3- Persimmon and fresh ginger swirled with peach candy and fall spices
031
Jobe Ritchie @jobeneuro.bsky.social · 29/11/2024
All my life, I was a canned cranberry sauce enjoyer. This year, we made it from scratch, and it is INCREDIBLE! Highly recommend.
010
Jobe Ritchie @jobeneuro.bsky.social · 24/11/2024
Tonight's beautiful sky prompted my first post. Glad to be here. #northcarolina #chapelhill
Sunset over Chapel Hill North Carolina.Sunset over Chapel Hill North Carolina.
140