Leopardus tilcayo is smaller than a housecat and covered in leopard-like spots. Plus, the brain might spawn from two types of precursor cell and how to maintain the foundations of human flourishing in...

A scientist in training seeks help in finding a new adviser without damaging existing working relationships.

In a deterministic, non-chaotic system, the initial state fixes the future completely, yet that future may be impossible to forecast from it. Using a cellular automaton of communicating cells, this st...

This article reviews the emergence and current status of synthetic biology in Spain, tracing its evolution from pioneering contributions in gene regulation, systems biology and microbial engineering ...

Awards that celebrate humour, curiosity and irreverence are a balm in hard times.

The leaf sheep, a neon green solar-powered slug, has inspired at least one Pokémon character and triumphs in global ballot

Scientists share help and advice on how they got their research discussions flowing.

Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...

The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

QED Science says that its metrics reduce bias by assessing papers solely on the basis of their originality and validity.

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Integrin adhesions allow dynamic cell-matrix interactions to regulate cell behaviour. Here, the authors reveal that tensin 1, a multidomain adaptor protein, forms condensates in cells that act as reve...

High temperatures make cell membranes weak and leaky. Rice plants rapidly counteract this effect by adjusting membrane lipid content, enabling them to resist heatwaves.

Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology. However, the global interaction landscape of human SLiMs remains...

Researchers from the German Cancer Research Center (DKFZ), the HI-STEM* Stem Cell Institute, and the Heidelberg University Hospital (UKHD) have developed “HemaGuide,” an AI assistant that supports phy...

Coffee plants are critically endangered by climate change. Researchers are finding solutions to keep scientists supplied with their favourite discovery fuel.

The prestigious European Molecular Biology Organization (EMBO) has elected Prof. Sebastian Hiller from the Biozentrum as a new member.

Genome-scale metabolic models (GSMMs) are important aids towards system-level understanding of the metabolic physiology of the gut microbes and for rational microbiome engineering. While large-scale r...

The new EMBO Members and Associate Members are recognized for their outstanding achievements in the life sciences

In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…

We applied an ultra-sensitive, histomorphology-guided spatial proteomics workflow to advanced atherosclerotic carotid plaques to define molecular changes associated with minimum fibrous-cap thickness....

Analysis of more than two dozen new genomes suggests our closest cousins remained genetically healthy, just before they vanished

Analysis of fossil proteins deepens mystery of the enigmatic Homo naledi

The exchange of biological matter between bacterial cells drives adaptation and evolution. However, whether bacteria can exchange functional proteins remains unclear. In this work, we found that antib...

Interactions between the tumor microenvironment and antibody drugs are imaged with spatial proteomics.

The two collaborators received the award for their contributions to the field of evolutionary cell biology, focusing on the origins of nuclear organisation and multicellularity, respectively.