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Maria Antonietta Tosches

@matosches.bsky.social
349 followers 327 following 32 posts

Associate Professor @ Columbia University. Brain evolution, plasticity and regeneration. www.tosches-lab.com

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Reposted by Maria Antonietta Tosches
bioRxiv Genetics @biorxiv-genetic.bsky.social · 28/09/2026
Generation of a transgenic cephalopod www.biorxiv.org/content/10.64898/20…
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John Tuthill @tuthill.bsky.social · 26/09/2026
this story about @couchmicroscopy.bsky.social captures science at its best: a scrappy team, a homemade microscope in a motel room, working under funding duress, pursuing a fundamental question about the evolution of photosynthetic organelles. www.nytimes.com/2026/09/26/s...
nytimes.com
In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life
A scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet.
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Portugues Lab @portugueslab.bsky.social · 24/09/2026
The Department of Neurobiology and Behavior at Cornell University is hiring! Come and do cutting edge research on the neural basis of natural behaviors at NBB (nbb.cornell.edu). No animal too small, no behavior too strange! Apply here: academicjobsonline.org/ajo/jobs/32592
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EMBL @embl.org · 21/09/2026
There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss
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Justus Kebschull @justuskebschull.bsky.social · 21/09/2026
NEW PREPRINT! An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
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Pawel Burkhardt @pawelburkhardt.bsky.social · 16/09/2026
Lovely to see several pieces of our ctenophore work featured in this beautiful new story from @quantamagazine.org 🪼 Great piece by @mstarling.bsky.social, also featuring work by @stevehaddock.bsky.social, @arnausebe.bsky.social & @hejnol.bsky.social. www.quantamagazine.org/ctenophores-...
quantamagazine.org
Ctenophores Aren’t Just Beautiful. They’re Biological Wonders. | Quanta Magazine
Comb jellies are helping answer fundamental questions in biology, from how the earliest nervous systems evolved to how bioluminescence works.
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Josh Barber @joshbarbershop.bsky.social · 15/09/2026
Lanternfish and the Deep Scattering Layer! Go check out the episode with @drandrewthaler.bsky.social ! #deepsea #ocean #fish #aquarium #science
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Andres Bendesky @bendeskylab.com · 11/09/2026
We have a tenure-track faculty position in Evolutionary Biology in Columbia's E3B Department. Application deadline is October 15. Come be our colleague. Please RT! apply.interfolio.com/193016
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Luis Alberto Bezares Calderón @lbezarescalderon.bsky.social · 16/08/2026
Our team is recruiting a PhD student to investigate the evolution of pressure sensation in Zooplankton! The project will use marine invertebrate larvae to explore the molecular, cellular, and neuronal mechanisms behind this fascinating sensory system. More details here: bit.ly/3TTeF4Q
bit.ly
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salamandermeeting2026.bsky.social @salamander2026.bsky.social · 14/08/2026
Join us! #SalamanderMeeting2026 REGISTRATIONS OPEN!! 🔽🔽🔽🔽🔽🔽🔽 salamander2026.iibiomedicas.unam.mx/inicio
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kdelmore.bsky.social @kdelmore.bsky.social · 28/07/2026
🧠🧬🦤 Excited to be at #ICN2026! We're recruiting a #postdoc to study the neural and molecular basis of migration. Projects could include field experiments, captive studies, and spatial/single-cell. Stop by poster 72 today or email! @zuckermanbrain.bsky.social #neuroethology delmorelab.com/recruitment
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Maria Antonietta Tosches @matosches.bsky.social · 27/07/2026
Excited to share a new preprint from the lab, by @andrewmatheson.bsky.social and team, where we dive into the superpower of newts: plasticity! www.biorxiv.org/content/10.6... Like many good projects, this started with a serendipitous observation... 🧵1/5
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Maria Antonietta Tosches @matosches.bsky.social · 27/07/2026
Congratulations to lab members @andrewmatheson.bsky.social , Tori Saltz and recent alumna @ecbjaeger.bsky.social on their #ICN2026 awards! Keep an eye on these rising stars and don't miss Andrew's and Tori's talks at @neuroethology.org this week
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Luis Guerra @luisguerra.bsky.social · 06/07/2026
Prebilaterian Origin of Monoaminergic Signalling is out! This paper represents four years of work, not only mine, but friends and colleagues. I am particularly grateful to Tatiana Mayorova; without her help, this paper would not have been nearly as complete. www.sciencedirect.com/science/arti...
sciencedirect.com
Prebilaterian origin of monoaminergic signaling
Monoamines such as serotonin, dopamine, and tyramine regulate physiological and behavioral processes in bilaterian animals, but the evolutionary origi…
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Emre Yaksi @emreyaksi.bsky.social · 02/07/2026
I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.
science.org
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...
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Maria Antonietta Tosches @matosches.bsky.social · 30/06/2026
It is a huge honor to become an EMBO Associate Member. I am grateful to my mentors and to all the brilliant trainees in my lab.
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Maria Antonietta Tosches @matosches.bsky.social · 29/06/2026
Better late than never... an update on the recent work from the lab. First of all, the Foundation: @astridd93.bsky.social phenomenal paper on the evolution of layering in the cerebral cortex 🧵1/7 www.biorxiv.org/content/10.1...
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Matthew Cobb @matthewcobb.bsky.social · 24/06/2026
I disagree. Is head is full of tadpoley thoughts, unknown and unimaginable.
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Maria Antonietta Tosches @matosches.bsky.social · 11/04/2026
Looking forward to presenting our latest work in Seattle!
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Giordano Lippi @lippilab.bsky.social · 24/02/2026
Chuffed to see our paper with @geneyeo.bsky.social finally published in @nature.com. www.nature.com/articles/s41... Very grateful to Fede, Susie, and Dave from my lab, and Sammi, Eric, and Pratibha from Gene's lab. What did we find? ⬇️ ⬇️ ⬇️
nature.com
Single-cell and isoform-specific translational profiling of the mouse brain - Nature
Post-transcriptional regulation of mRNA translation was explored using Ribo-STAMP and single-cell RNA sequencing to reveal cell-type-specific and isoform-specific translation patterns across hipp...
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Steven Salzberg @stevensalzberg.bsky.social · 16/01/2026
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
embl.org
In remembrance of Peer Bork  | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
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Maria Antonietta Tosches @matosches.bsky.social · 09/01/2026
Thank you @fredcauseret.bsky.social for this nice highlight of our work and @idoiaeu.bsky.social 's!
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Maria Antonietta Tosches @matosches.bsky.social · 17/12/2025
This is so true!
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Maria Antonietta Tosches @matosches.bsky.social · 16/11/2025
Excited to present our recent work at #SfN25 's Evolutionary Neurogenomics session this Tuesday!
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Andres Bendesky @bendeskylab.com · 21/10/2025
New faculty job opening at @zuckermanbrain.bsky.social @columbiauniversity.bsky.social Come be our colleague! Application deadline: November 22 apply.interfolio.com/176153
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Maria Antonietta Tosches @matosches.bsky.social · 04/09/2025
Looking forward to speaking at the next TIBBE seminar!
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eLife @elife.bsky.social · 01/09/2025
Scientists have mapped the entire connectome of a 3-day-old marine worm larva (Platynereis dumerilii), including over 9,000 cells and 200+ neuronal types. This resource can help us understand how nervous systems evolved and coordinate whole-body movement. buff.ly/IPxFCHs
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Maria Antonietta Tosches @matosches.bsky.social · 25/08/2025
Excited to share our latest work on brain evolution, where we dive into the evolution of Cajal-Retzius cells! If you are interested in cell type evolution and cerebral cortex evo-devo, please read on… www.biorxiv.org/content/10.1... 🧵 1/7
biorxiv.org
Evolution of Cajal-Retzius Cells in Vertebrates from an Ancient Class of Tp73+ Neurons
In the developing cerebral cortex, Cajal Retzius (CR) cells are early-born neurons that orchestrate the development of mammalian-specific cortical features. However, this cell type has not been conclu...
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Maria Antonietta Tosches @matosches.bsky.social · 14/08/2025
So true!
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EMBL @embl.org · 07/08/2025
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠 Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels. Take a look at these four open positions 👇
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A. Sánchez Alvarado @planaria1.bsky.social · 06/08/2025
Evolution’s eye game is wild, but mollusks take it to another level CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates rdcu.be/ezw0t
url.us.m.mimecastprotect.com
A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
Nature Communications - Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these...
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Steven Cook @dumpyunc.bsky.social · 31/07/2025
Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...
science.org
Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution
Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 25/06/2025
Today, the @fwf-at.bsky.social honors Elly Tanaka, IMBA's Scientific Director, with the Wittgenstein Award – the premier research award of Austria - for her groundbreaking discoveries in the field of regenerative biology. Congratulations, Elly! More on the award: imba.science/43Y93sC
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Lucia Prieto Godino @neuroluci.bsky.social · 12/06/2025
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇 bit.ly/44aVm9E
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Joshua Weitz @joshuasweitz.bsky.social · 02/06/2025
Get the word out far and wide. New opportunity from the Simons Foundation in the Eco-Evo space. 2026 Simons Graduate Fellowship in Ecology and Evolution Awards, due July 31, 2025, only for incoming PhD students who plan to start their PhDs in Fall 2026. www.simonsfoundation.org/grant/simons...
simonsfoundation.org
Simons Graduate Fellowships in Ecology and Evolution
The purpose of these awards is to provide support for students entering U.S.-based Ph.D. programs with a plan to perform research in ecology and evolution. While we will consider all projects in ecolo...
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Science Magazine @science.org · 05/05/2025
The axolotl has the ability to regenerate its brain. Using single-cell transcriptomics, four Science studies in 2022 revealed evolutionary innovations in reptile and amphibian brains. Learn more during #AmphibianWeek: scim.ag/3EEKMxZ
The axolotl, represented here by the Mexican axolotl Ambystoma mexicanum, has the ability to regenerate its brain. In this 2022 issue, a group of four papers profiles amphibian and reptile brain neurons with single-cell transcriptomics. Analyses lend insight into why the axolotl brain retains regenerative capability that the mammalian brain has lost as well as how structural brain innovations arose during evolution.
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Debby Silver @debbysilver.bsky.social · 14/05/2025
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
nature.com
A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature
HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...
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Current Biology @currentbiology.bsky.social · 14/05/2025
Check out our latest issue to read a Q&A with @thibautbrunet.bsky.social, who studies the evolutionary origin of animal morphogenesis at the Institut Pasteur. www.cell.com/current-biol...
cell.com
Thibaut Brunet
Interview with Thibaut Brunet, who studies the evolutionary origin of animal morphogenesis at the Institut Pasteur.
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Oliver Harschnitz @harschnitz.bsky.social · 01/05/2025
Wonderful work by @nataliabaumann.bsky.social & the @djabaudon.bsky.social team showing how progenitor metabolism regulates region-specific neurogenesis! Glad our group could contribute, thanks to Eleonora Conti & Roberto Sansevrino. www.cell.com/cell/fulltex...
cell.com
Regional differences in progenitor metabolism shape brain growth during development
Brain-wide birthdate mapping reveals that while hindbrain neurogenesis is transient, forebrain neurogenesis is temporally sustained through spatiotemporal regulation of progenitor mitochondrial functi...
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Giacomo Gattoni @giacomogattoni.bsky.social · 24/04/2025
New preprint from my PhD in @amphispacelab.bsky.social is out! 🥳 We investigated the evolution of my favorite gene FoxQ2 across 21 animal phyla, and found three ancient paralogs with a very dynamic history. More on phylogeny, synteny, and comparative in situs in the 🧵 below! tinyurl.com/2j96px45
tinyurl.com
Evolutionary dynamics of FoxQ2 transcription factors across metazoans: A tale of three ancient paralogs
FoxQ2 is a highly conserved class of Forkhead-box transcription factors expressed on the anterior side of the body in cnidarians and bilaterians. Despite this conserved expression pattern, recent phyl...
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International Society for Neuroethology @neuroethology.org · 16/04/2025
Please mark your calendars and join us next May 20th in the next session of the webinar series "The future of Neuroethology". We will have a line-up of amazing scientists as usual, we will learn about locusts, newts and cichlids!
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Sara Zeppilli @sarazeppilli.bsky.social · 08/04/2025
Happy to see my PhD work in the Fleischmann lab at Brown University @carneyinstitute.bsky.social published in @natureneuro.bsky.social! -Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution nature.com/articles/s41...
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Giordano Lippi @lippilab.bsky.social · 02/04/2025
Delighted to see our paper finally out in @cp-neuron.bsky.social! Together with Ian MacRae, we developed a new toolbox to study microRNAs and used it to find new mechanisms of Purkinje cell development. Please see the tweetorial from researcher extraordinaire @norjin.bsky.social for details.
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