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Manx Neurobiologist

@garyrlewin.bsky.social
277 followers 105 following 32 posts

Manxman Scientist. Neurobiologist, Group Leader, Interests: ion channels, extreme biology, mole-rats, sensory transduction, touch, pain, social brain, flying www.mdc-berlin.de/lewin

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Mohammed Khallaf @khallaf.bsky.social · 21/08/2026
How do you recognize who’s who when you live mostly in the dark? 👂👃✋ Our review explores how naked mole-rats use sound, smell, and touch to maintain their remarkable social organization! www.sciencedirect.com/science/arti... @garyrlewin.bsky.social, Firdevs Murad, Wenhan Luo, Alison Barker
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Manx Neurobiologist @garyrlewin.bsky.social · 12/08/2026
Watched an almost total eclipse on the same day as our first ever cover in Nature! The universe is definitely a fan of naked mole-rats.
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Manx Neurobiologist @garyrlewin.bsky.social · 15/07/2026
For me this paper is a career highlight..truly astonishing biology! www.nature.com/articles/s41...
nature.com
A queen odour mediates reproductive suppression in a eusocial mammal - Nature
Naked mole-rat (Heterocephalus glaber) queens produce isopropyl myristate, a low-volatility ester that high-ranking animals detect and avoid, which alters prolactin and progesterone in other females t...
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Mohammed Khallaf @khallaf.bsky.social · 15/07/2026
Our new paper is out in @nature.com! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜 @garyrlewin.bsky.social youtu.be/enfv3zJrWKM?...
youtu.be
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
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Manx Neurobiologist @garyrlewin.bsky.social · 05/07/2026
www.nature.com/articles/s41...
nature.com
Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA - Nature Communications
The long-living rodent naked mole-rat has a distinct break in its 28S ribosomal RNA. Here, the authors present cryo-EM structures showing this cleavage is stabilized by surrounding ribosomal proteins,...
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Manx Neurobiologist @garyrlewin.bsky.social · 08/06/2026
www.mdc-berlin.de/news/news/ga... It is a great honour to be elected to the Leopoldina. I am pretty sure I am the first Manxman to be elected to this august body!
mdc-berlin.de
Gary Lewin elected new Leopoldina member
Congratulations to Gary Lewin on his election as a new member of the German National Academy of Sciences Leopoldina! The prestigious honor recognizes his scientific accomplishments over the span of hi...
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Manx Neurobiologist @garyrlewin.bsky.social · 08/06/2026
@mdc-berlin.bsky.social
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Reposted by Manx Neurobiologist
NYU Pain Research Center @nyupainresearch.bsky.social · 19/05/2026
New research maps the proteomes of individual sensory neuron subtypes, revealing how protein-level changes drive nociceptor sensitization, opening fresh avenues for #painresearch. @garyrlewin.bsky.social @amapruns.bsky.social
buff.ly
Deep visual proteomics uncovers nociceptor diversity and pain targets - Nature Communications
Sensory neuron subtypes are defined by transcriptomics, but their proteomic identities remain unclear. Here, authors show distinct protein signatures of electrophysiologically defined nociceptors and…
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Professor Plink @professorplink.bsky.social · 27/04/2026
No greater deconversion tool than the bible.
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Manx Neurobiologist @garyrlewin.bsky.social · 15/04/2026
Looking forward to this!
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Manx Neurobiologist @garyrlewin.bsky.social · 13/04/2026
@mdc-berlin.bsky.social Excited to see our paper with Sam @amapruns.bsky.social and Fabian Coscia now published. www.nature.com/articles/s41...
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Manx Neurobiologist @garyrlewin.bsky.social · 13/04/2026
www.mdc-berlin.de/news/press/f...
mdc-berlin.de
First “protein map” of neurons that initiate pain
Joint press release by the Max Delbrück Center and the Helmholtz Centre for Infection Research
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Manx Neurobiologist @garyrlewin.bsky.social · 09/01/2026
The relative calmness of Americans spooks me. If my government decided to murder its citizens in cold blood we would be pissed! But never happened, recently at least...
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Manx Neurobiologist @garyrlewin.bsky.social · 15/11/2025
Properly published! Mechanosensitive currents in sensory neurons lacking PIEZO2 www.cell.com/biophysj/ful...
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Manx Neurobiologist @garyrlewin.bsky.social · 04/11/2025
Published! Check out our latest work on sensory mechanotransduction. PIezo2 gene deletion barely impacts mechanically-activated currents in mouse sensory neurons. Is the cell body a good model for in vivo transduction? www.cell.com/biophysj/pdf...
cell.com
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Manx Neurobiologist @garyrlewin.bsky.social · 29/10/2025
We were very happy to help, in a very small way, in getting this beautiful structure out. The structure is remarkably conserved considering the famous 28S ribosomal RNA split. I suspect that the split has as yet unknown biological repercussions in this remarkable animal..
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Manx Neurobiologist @garyrlewin.bsky.social · 26/10/2025
Check out this new paper from Stefan Lechner's lab showing with minflux nanoscopy how PIEZO1 channels cluster and invagininate the membrane. Glad we could make a small contribution to this nice story! www.science.org/doi/full/10....
science.org
Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells
MINFLUX nanoscopy reveals subcellular distribution and conformational diversity of PIEZO1 channels in intact cells.
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Manx Neurobiologist @garyrlewin.bsky.social · 02/10/2025
Sam has now started her new group at the Helmholtz Center for Infection Research Diseases. Congratulations! I wish her the very best for her independent career. The time Sam spent with us was hugely successful in many respects and we will all be sad to see her go..
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Manx Neurobiologist @garyrlewin.bsky.social · 04/08/2025
Widely accepted findings should be validated. For example, mechanically-activated currents (MA-currents) in sensory neurons depend on PIEZO2..right?. Here we show that PIEZO2 is NOT associated with a huge loss of MA-currents in sensory neurons. #ion channels #sensory www.biorxiv.org/content/10.1...
biorxiv.org
Mechanically-gated currents in mouse sensory neurons lacking PIEZO2
Touch sensation starts with the opening of mechanically-gated activated ion channels at neuroglial endings of mechanoreceptors in the skin. The function of around half of low threshold mechanoreceptor...
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Manx Neurobiologist @garyrlewin.bsky.social · 06/07/2025
bbc.com/news/article... I worked as a tram driver for two summers with this fella (nearly 40 years ago!)...he is right, best job I ever had
bbc.com
Driver celebrates 'unbelievably unique' 50-year horse tram career
Tram driver Peter Cannon is celebrating half a century working on the Douglas Bay Horse Tramway.
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Manx Neurobiologist @garyrlewin.bsky.social · 30/06/2025
Read about how a book about extraordinary animals with Russ Hodge and Kat Menschik came to be. www.stiftung-charite.de/en/our-fundi....
stiftung-charite.de
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Max Delbrück Center @mdc-berlin.bsky.social · 29/06/2025
This has been a great #lndw25 on @campusbuch.bsky.social! Thank you for everyone who made this happen! 🎉
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Catherine Dulac @dulaclab.bsky.social · 20/06/2025
Wonderful visit @mdc-berlin.bsky.social thanks @hannahornberg.bsky.social for the invitation and congrats @khallaf.bsky.social for showing me such cool data on naked mole rats!
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Manx Neurobiologist @garyrlewin.bsky.social · 27/06/2025
Proud to a part of this great study from the lab of Annette Hammes. A new role for mechanosensitive PIEZO2 channels in the development of the coronary arteries. www.nature.com/articles/s44...
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Reposted by Manx Neurobiologist
Max Delbrück Center @mdc-berlin.bsky.social · 26/05/2025
#LNDW is celebrating 25 years of science and discovery – with a special reduced price of one night for just €5. The #mdcBerlin and others open their labs on June 28, 2025. Visit us at #CampusBuch! Our full program here 👉 www.mdc-berlin.de/long-night-s... 👈
Graphic with image and text: The image shows a green abstract background with fine black and dark green thread-like lines radiating outward from a central area. A beige border surrounds the image, with repeated text "#LNDW25 | 25 YEARS" in various shades of green and red. The overlaid text reads "LONG NIGHT OF SCIENCE" in white, all-caps, sans-serif font on a red rectangular background near the top. Centered is a large white "€5". Below, "CAMPUS BUCH" and "JUNE 28, 2025" appear in white, all-caps font on red background boxes.
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Manx Neurobiologist @garyrlewin.bsky.social · 14/05/2025
I left my 50s today..celebrated by walking to the top of Snaefell. The top of the lovely Isle of man.
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Manx Neurobiologist @garyrlewin.bsky.social · 08/05/2025
Back in Pretoria for more mole-rat fun..special smell and touch abilities to be measured!
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Max Delbrück Center @mdc-berlin.bsky.social · 10/04/2025
From an #AI-powered search engine for omics data to a scalable drug screening platform for neuromuscular diseases – 4 of our labs present their projects at @biovaria.bsky.social #techtransfer networking event! www.biovaria.org/ @danilexn.bsky.social@nukappa.bsky.social @garyrlewin.bsky.social
Technology Transfer: Our innovations at Biovaria. Munich, 28 - 29 April
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Manx Neurobiologist @garyrlewin.bsky.social · 31/03/2025
physoc.onlinelibrary.wiley.com/doi/full/10.... Our latest paper is now published, open access of course. Check it out! Mechanotransduction and regeneration! More to come soon..
physoc.onlinelibrary.wiley.com
The mechanotransduction protein STOML3 is required for proprioceptor plasticity following peripheral nerve regeneration
Nerve regeneration is associated with the plasticity of sensory neurons such that even muscle afferents directed to the skin form mechanosensitive receptive fields appropriate for the new target. STO...
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Reposted by Manx Neurobiologist
Mohammed Khallaf @khallaf.bsky.social · 26/03/2025
Honored to present my work on naked mole rats from @garyrlewin.bsky.social at the @modolfor.bsky.social symposium (@silkesachse.bsky.social) during the Göttingen Neuroscience Meeting #NWG @neurowissg.bsky.social —and finally getting the famous and amazing Drosophila from @katrinvogt.bsky.social!!
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Manx Neurobiologist @garyrlewin.bsky.social · 16/03/2025
This came out today a 26 min interview with me about touch. In German. It turned out pretty good #pain #painresearch #touch www.ardaudiothek.de/episode/wiss...
ardaudiothek.de
Podcast: Faszination Tastsinn: Wie wir fühlen und be-greifen
Der Neurobiologe Gary Lewin erforscht am Max-Delbrück-Zentrum die Geheimnisse unseres Tastsinns und kommt dabei dem Geheimnis, wie unser Fühlen funktioniert, näher. Von Anna Corves
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Manx Neurobiologist @garyrlewin.bsky.social · 20/11/2024
Looking forward to a mole-rat bonanza next week! mpinb.mpg.de/en/events/ev...
mpinb.mpg.de
BIOMORA24 - Unique Biology of Mole-Rats - MAX PLANCK INSTITUTE FOR NEUROBIOLOGY OF BEHAVIOR — CAESAR
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Manx Neurobiologist @garyrlewin.bsky.social · 15/11/2024
www.bbc.com/news/article... Wallabies are taking over the Isle of Man!
bbc.com
Survey shows Isle of Man wild wallaby population likely at 1,000
The latest drone survey finds a further 297 of the animals outside of the Ballaugh Curraghs area.
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Manx Neurobiologist @garyrlewin.bsky.social · 15/11/2024
www.bcf.uni-freiburg.de/ringvorlesun... Will be giving a public lecture on touch next monday, in Freiburg!
bcf.uni-freiburg.de
Gary Lewin, Max-Delbrück-Center Berlin: Berührung auf molekularer Ebene — Bernstein Center Freiburg
Molekulare Physiologie der somatosensorischen Wahrnehmung | Max-Delbrück-Center | Berlin [Ringvorlesung]
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