iiinova — where your digital self keeps evolving

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Paul Thompson @ptenigma.bsky.social · 29/08/2026

I'm going to have to update my neurogenetics class in the Fall with this cool new result (July Nature Medicine): 🔥a 34-circRNA "circular RNA" blood signature detected biomarker-confirmed Alzheimer’s disease with AUC=0.945 ...

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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 06/07/2026

Have a favorite European colleague who should be recognized for their work in non-medical biotechnology? Pls nominate them for the Novo Nordisk Foundation Prize for Biotechnology. (Prior awardees at novonordiskfoundationprize.com/awardees). Thank you! novonordiskfoundationprize.com/nominate-bio...

novonordiskfoundationprize.com

The Novo Nordisk Foundation Prize

Our prizes are awarded to researchers who have contributed to scientific breakthroughs or in other ways distinguished themselves within natural or medical science.

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Monika Piwecka @monikapiwecka.bsky.social · 05/03/2026

Not much time left... but still! Please share/circulate or apply!

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Carmelo Ferrai @carmeloferrai.bsky.social · 05/03/2026

👇🏽👇🏽👇🏽👇🏽👇🏽

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Monika Piwecka @monikapiwecka.bsky.social · 05/03/2026

Not much time left... but still! Please share/circulate or apply!

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meisterlab.bsky.social @meisterlab.bsky.social · 04/03/2026

Exciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇

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Joanna Bagniewska @joannabagniewska.com · 12/02/2026

Let's celebrate #DarwinDay by reminding ourselves that everyone has moments when they feel worse for wear. Darwin wrote to Charles Lyell in 1861: "But I am very poorly today & very stupid & hate everybody & everything." www.darwinproject.ac.uk/letter/DCP-L... So, hang in there, #academicsky! 🧪🌏🐵

Handwritten note saying: "But I am very poorly today & very stupid & hate everybody & everything."

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Live With MS @livewithms.bsky.social · 08/02/2026

When insomnia hits, it’s not just “having trouble sleeping.” For many people with MS, it’s a brain that won’t slow down, a body that feels wired and exhausted at the same time, and nights that don’t offer real rest.

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EMBO @embo.org · 27/01/2026

Sign up now for the EMBO Workshop "#RNA metabolism: Perspective from physiology to brain disorder" in Darjeeling, India, 25–28 October 2026. Deadline: 15 May 2026 meetings.embo.org/event/26-rna-meta… #EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪

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Monika Piwecka @monikapiwecka.bsky.social · 06/01/2026

New year and new opportunities! There is an open call for a PhD student to join our lab. #RNA biology #circRNAs #miRNAs #neuroscience #neuroedocrinology Please share with potential candidates 🙏🫶. A link to the call & more details here: www.phdscanner.com/opportunitie...

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Matthew L. Kraushar @matthewkraushar.bsky.social · 15/01/2026

yo 🦋 NEURO SKY 📣 the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists! youngpisymposium2026.com

youngpisymposium2026.com

Young PI Symposium 2026

Visit the post for more.

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Mike Fainzilber @mfainzilber.bsky.social · 15/01/2026

🧪 An EMBO Meeting on Axon Biology in Okinawa, Japan Iconic science at an amazing venue. Please join us! EMBO | COB Workshop on Axonal degeneration and regeneration meetings.embo.org/event/26-axo...

meetings.embo.org

Axonal degeneration and regeneration

Neurons are the largest and most long-lived class of cells, necessitating specialized mechanisms for their survival, growth and maintenance. Axons are the longest extensions of a neuron, reaching len…

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Monika Piwecka @monikapiwecka.bsky.social · 06/01/2026

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Jakob Farnung @jakobfarnung.bsky.social · 06/01/2026

When RNA Degradation 🤝 meets 🤝 Protein Degradation! tinyurl.com/E3TDMD In a collaboration of @bartellab.bsky.social and Schulman lab, we show that, in target-directed microRNA degradation (TDMD), 2-RNA-factors recruit an E3 ligase and induce the degradation of not only a protein but also RNA (1/5).

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Jeroen Pasterkamp @jeroenpasterkamp.bsky.social · 13/12/2025

Exciting opportunity to learn about #humanbrainmodels and #singlecelltechnology! July 13-17 2026 we for the first time will offer the Utrecht Summer School titled "Advanced human brain models in the single-cell era" for master and PhD students. Apply now: utrechtsummerschool.nl/courses/life...

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Kim Lane Scheppele @kimlanelaw.bsky.social · 10/12/2025

All travelers from ESTA countries (yes the ones on visa waiver programs) will have to disclose 5 years of social media + huge amounts of personal data to enter the US now. All US academic associations should now meet outside the US if we want to meet our international colleagues.

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Matthew Taliaferro @jmtali.bsky.social · 08/12/2025

Announcing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!

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Lerit Lab @lablerit.bsky.social · 08/12/2025

Join us in Porto for the forefront of RNA localization & local translation research! Registration is live!

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Ares Lab @areslab.bsky.social · 09/12/2025

Hey everyone, the RNA Society is running an RNA Infographic Contest! Get your team together and create! There are prizes!

A graphic including a QR code that describes the RNA Society's Infographic contest.

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Trends in Genetics @cp-trendsgenetics.bsky.social · 05/12/2025

"Features and biomedical relevance of circular RNA biogenesis" by Xiaolin Wang & Ge Shan "Recently, modulation of circRNA biogenesis to generate tissue-specific expression patterns is coming into focus. We summarize various mechanisms involved..." authors.elsevier.com/sd/article/S...

Figure 1. Mechanisms of biogenesis of circular RNA (circRNA) subclasses and the biomedical relevance of the RNA-binding proteins (RBPs) involved.

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Ivano Legnini @ilegnini.bsky.social · 04/12/2025

Still a couple of weeks to apply for a fully funded PhD position in #AI and #RNA biology!!!

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Patri Álvarez-Campos @patrialvarezcam.bsky.social · 14/11/2025

Join our upcoming course on cutting-edge evolutionary & genomic methods for Evo-Devo studies! We'll cover: comparative & single-cell transcriptomics,ATAC-seq, phylogenomics, comparative genomics, gene regulation, and much more Spots still available: sites.google.com/view/evodevo...

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Stefan Marciniak @profmarciniak.bsky.social · 15/11/2025

Some good news New data published by the UK Health Security Agency (UKHSA) shows the 2025/26 vaccine is currently 70 to 75% effective at preventing hospital attendance in children aged 2 to 17 years and 30 to 40% effective in adults. www.gov.uk/government/n...

gov.uk

Flu vaccine providing important protection despite new subclade

UKHSA’s early season data shows vaccination remains best defence alongside good respiratory hygiene as flu activity rises.

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Emilio Mármol Sánchez @marmole6.bsky.social · 14/11/2025

🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social www.cell.com/cell/fulltex... If you want to know more, read the 🧵 below:

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Mark A. Hanson @hansonmark.bsky.social · 11/11/2025

We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing: a 🧵 1/n Drain: arxiv.org/abs/2511.04820 Strain: direct.mit.edu/qss/article/... Oligopoly: direct.mit.edu/qss/article/...

A table showing profit margins of major publishers. A snippet of text related to this table is below.

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.

A figure detailing the drain on researcher time.

1. The four-fold drain

1.2 Time
The number of papers published each year is growing faster than the scientific workforce,
with the number of papers per researcher almost doubling between 1996 and 2022 (Figure
1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material
has aligned well with the competitive prestige culture in which publications help secure jobs,
grants, promotions, and awards. To the extent that this growth is driven by a pressure for
profit, rather than scholarly imperatives, it distorts the way researchers spend their time.
The publishing system depends on unpaid reviewer labour, estimated to be over 130 million
unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of
peer-review for decades, but the scale of the problem is now worse, with editors reporting
widespread difficulties recruiting reviewers. The growth in publications involves not only the
authors’ time, but that of academic editors and reviewers who are dealing with so many
review demands.
Even more seriously, the imperative to produce ever more articles reshapes the nature of
scientific inquiry. Evidence across multiple fields shows that more papers result in
‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow
progress until one considers how it affects researchers’ time. While rewards remain tied to
volume, prestige, and impact of publications, researchers will be nudged away from riskier,
local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with
limited progress whereas core scholarly practices – such as reading, reflecting and engaging
with others’ contributions – is de-prioritized. What looks like productivity often masks
intellectual exhaustion built on a demoralizing, narrowing scientific vision.

A table of profit margins across industries. The section of text related to this table is below:

1. The four-fold drain
1.1 Money
Currently, academic publishing is dominated by profit-oriented, multinational companies for
whom scientific knowledge is a commodity to be sold back to the academic community who
created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis,
which collectively generated over US$7.1 billion in revenue from journal publishing in 2024
alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit
margins have always been over 30% in the last five years, and for the largest publisher
(Elsevier) always over 37%.
Against many comparators, across many sectors, scientific publishing is one of the most
consistently profitable industries (Table S1). These financial arrangements make a substantial
difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor &
Francis revenues were generated in North America, meaning that North American
researchers were charged over US$2.27 billion by just two for-profit publishers. The
Canadian research councils and the US National Science Foundation were allocated US$9.3
billion in that year.

The costs of inaction are plain: wasted public funds, lost researcher time, compromised
scientific integrity and eroded public trust. Today, the system rewards commercial publishers
first, and science second. Without bold action from the funders we risk continuing to pour
resources into a system that prioritizes profit over the advancement of scientific knowledge.

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EMBL Events @events.embl.org · 13/11/2025

How to tackle emerging questions in cellular organisation, adaptation, and robustness? Join #EESPhaseSeparation! 🧬🦠 Bringing together scientists from diverse fields to foster new discoveries in condensate biology. Submit your abstract by 10 Feb: s.embl.org/ees26-08-bl 📅 19 – 22 May 2026

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BioVoxxel (Jan Brocher) @biovoxxel.de · 10/11/2025

Ever wondered if analyzing your images by using intensity Z-projections impacts your data? Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis! buff.ly/KJ147tI #Microscopy #ZProjection #ImageAnalysis

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Davit Potoyan @potoyan.bsky.social · 04/11/2025

Our RNA condensate work is finally out! Using simulations, we uncover the origin of the lower critical solution temperature (LCST) behaviour underlying thermo, iono-sensing functions in pure RNA condensates. www.pnas.org/doi/10.1073/...

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Janusz M. Bujnicki @jmbujnicki.bsky.social · 25/10/2025

Exciting news for the RNA research community! The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130... #RNA #bioinformatics #RNAstructure #modomics

genomebiology.biomedcentral.com

Unlocking the regulatory code of RNA: launching the Human RNome Project - Genome Biology

The human RNome, the complete set of RNA molecules in human cells, arises through complex processing and includes diverse molecular species. While research traditionally focuses on four canonical nucl...

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Adrian Woolfson @adrianwoolfson.bsky.social · 01/11/2025

An extraordinary result for ipilimumab immunotherapy given as a first line therapy for glioblastoma share.google/485XFZxmBm26...

share.google

Dad’s aggressive brain cancer vanishes after taking new drug

The NHS is now looking for patients with glioblastoma to take part in a new drug trial

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Piotr Ziolkowski @piotraz.bsky.social · 25/10/2025

⏰ Last week to apply! Don’t miss the chance to join our lab and explore the fascinating world of meiotic recombination 🌿 👉 Deadline: Nov 1, 2025

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Jason Shepherd @jasonsynaptic.bsky.social · 20/10/2025

For obvious reasons, I've become fascinated with retrotransposons. So we ( @alexwhiteley.bsky.social and I) wrote an article now out in Neuron @cellpress.bsky.social on how we think retrotransposons influence brain function and health! kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

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RNAcentral @rnacentral.bsky.social · 08/10/2025

🎉 RNAcentral Release 26 is here! This release introduces our biggest structural change yet: gene-level entries for ncRNAs across 204 organisms. For the first time, you can explore RNA data at the gene level, not just individual sequences. 🧵👇

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Jörg Vogel @jorg-vogel-lab.bsky.social · 08/10/2025

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

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EMBO @embo.org · 06/10/2025

Want to connect with researchers in #GeneRegulation, small RNAs, #StructuralBiology and more? Sign up for EMBO Workshop "RNA-guided genome protection" in Caux, Switzerland, 16–20 June 2026! Deadline: 15 March meetings.embo.org/event/26-gen... #DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪

meetings.embo.org

RNA-guided genome protection

The genome carries information across generations, ensuring species survival. To preserve faithful transmission of genetic information, RNA-directed mechanisms safeguard the genome integrity in diver…

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Agata Starosta @agatastarosta.bsky.social · 29/09/2025

Nauka i badania, w kraju, który jest 20-tą gospodarką świata, powinny być priorytetem ponad podziałami. Apelujemy do wszystkich, którzy rozumieją potrzebę prowadzenia badań naukowych w Polsce o zapoznanie się z treścią listu i poparcie Apelu. www.petycjeonline.com/list_otwarty...

petycjeonline.com

List otwarty do Prezydenta RP, Marszałka Sejmu RP, Marszałka Senatu RP, Prezesa Rady Ministrów oraz Wiceprezesów Rady Ministrów w sprawie finansowania nauki, w tym zwłaszcza Narodowego Centrum Nauki

Szanowni Państwo, W niniejszej petycji prezentujemy List otwarty, który będzie wysłany do Kancelarii Prezydenta, Marszałków Sejmu i Senatu, Prezesa Rady Ministr&oacut...

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Carmen Falcone @carmenfalcone.bsky.social · 29/09/2025

Submit an abstract for our 2nd @italianglianetwork.bsky.social Symposium by Oct 10. We want to see your cool #glial research!!! The 2nd #IGN Symposium will be online on November 26 at 2 pm CET, and everybody can attend 😍 We will post the link to connect here: tinyurl.com/ye232mx9

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Markus Hafner @markushafnerrna.bsky.social · 27/09/2025

The specific motif built up by these two RBPs cannot be identified by studying each of them in isolation, so one important question we would like to raise is: How many RBPs form heteromultimeric complexes with specificity other than the sum of the individual RBPs?

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Luisa Cochella @lcochella.bsky.social · 03/09/2025

Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...

science.org

An ancient and essential miRNA family controls cellular interaction pathways in C. elegans

A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.

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ME Torres-Padilla @metorrespadilla.bsky.social · 12/06/2025

Are you @ the late stages of your postdoc ? Want to pursue a PI career ? Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum www.helmholtz-munich.de/en/stem-cell... Peer-networking / Career orientation and more !!! Please distribute :) 🙂

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Petr Svoboda @svobodalab.bsky.social · 28/08/2025

The Argonautes 2025 - we made a special gift for participants - a card set with 32 different Argonautes + an extension pack with four Nobel prize winners from the small RNA field. Mello, Fire, Ambros & Ruvkun as jokers :-) #argonautes2025

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Max Delbrück Center @mdc-berlin.bsky.social · 18/08/2025

Congratulations to Klaus Rajewsky, honored by EFIS with its first-ever Lifetime Achievement Award for his contributions to immunology. 🔗 www.mdc-berlin.de/news/news/kl...

Klaus Rajewsky recognized for lifetime achievements, shown in a portrait with text highlighting the honor.

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