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Petr Svoboda

@svobodalab.bsky.social
925 followers 295 following 515 posts

playful scientist cynical biologist nerdy nerd & teacher professor de La Mancha admiring humanity, curiosity & Yossarian Lord of Sealand husband & father citizen of Prague & peasant of Bohemia

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Reposted by Petr Svoboda
Maitreya Dunham @maitreya.bsky.social · 24/09/2026
Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.
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Harmit Singh Malik @harmitmalik.bsky.social · 22/09/2026
www.wbur.org/news/2026/08... Why a UMass researcher is among the dozens leaving the U.S. for Canada
wbur.org
Why a UMass researcher is among the dozens leaving the U.S. for Canada
A renowned scientist at UMass Chan Medical School is moving his lab to Canada. The Canadian government named RNA researcher Phillip Zamore among the first recipients of awards that will total more tha...
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Laura Ross @laurarossevo.bsky.social · 10/09/2026
My lab @ Edinburgh university is recruiting a postdoc to work on the weird and wonderful germline-specific chromosomes of flies. elxw.fa.em3.oraclecloud.com/hcmUI/Candid... collaboration with @germline.bsky.social and yukiko yamashita funded by @novonordisk.bsky.social please repost!
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Peter Andersen @germline.bsky.social · 08/09/2026
We are recruiting a PhD student 🥼🙋 Topic: how germ cells bend gene expression dogmas Fly genetics + proteomics + genomics. Fully funded. Aarhus University 🇩🇰 info on the project and how to apply👇 mbg.au.dk/en/peter-and... I'd really appreciate it if you'd help spread the word. Thanks
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Petr Svoboda @svobodalab.bsky.social · 08/09/2026
A bit of scientific pilgrimage today - I am giving a talk to lifesci PhD students from the University of Ostrava in Vrazne directly in the house where was born Gregor Johann Mendel.
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Darrin T. Schultz @dts.bsky.social · 19/08/2026
Our new paper in Science Advances asks how animals' genomes have changed since their origin from a common ancestor over 600 million years ago, and what patterns in their DNA have arisen in the churn of speciation and extinction. www.science.org/doi/10.1126/...
Five-panel diagram explaining fusion-with-mixing in chromosome evolution. Red and blue represent two different ancestral chromosomes throughout.

A, Fusion-with-mixing: a red chromosome and a blue chromosome fuse into one half-red, half-blue bar. Down the page, successive rows show inversions, drawn as X-shaped crossings between rows, progressively interleaving the two colors until the bottom bar is finely striped. A widening gray wedge labeled Entropy runs alongside an arrow marked Time plus evolution, pointing down.

B, Independent regulation: two separate chromosomes, one red and one blue. In each, a regulatory element, drawn as an oval, acts by an arrow on a gene within its own chromosome only.

C, FWM and novel regulation: on a fused, mixed chromosome, a red gene and a blue gene now sit next to each other across an inversion breakpoint. Red and blue arrows show regulatory elements reaching across it to act on the other chromosome's gene.

D, Regulatory entanglement: an extensively mixed chromosome, finely striped. Below it, a row of alternating red and blue genes is linked by a dense web of crossing curved arrows, so many overlapping regulatory connections that unmixing the chromosome would break them.

E, Emergence of entangled loci: a five-species phylogeny. A red and a blue chromosome fuse at an ancestral node, and helical icons on later branches mark continued mixing. Colored boxes mark four new red-blue regulatory interactions arising after inversions. Species A keeps its two chromosomes separate. In species B through E, the two earliest interactions, cyan boxes 1 and 2, are present in every descendant lineage, while later ones, yellow 3 and magenta 4, appear in fewer.
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Petr Svoboda @svobodalab.bsky.social · 27/07/2026
This week I'm acting as a substitute director for @imgprague.bsky.social I certainly did not expect that the first thing in this role will be ordering lowering flags for my colleague and friend. R.I.P. Pavel. Pavel Jungwirth (1966-2026)
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Institute of Molecular Genetics @imgprague.bsky.social · 27/07/2026
We are deeply saddened by the tragic passing of our colleague Professor Pavel Jungwirth. He inspired generations of scientists through his research, mentorship and unwavering commitment to science. Our sincere condolences to his family and colleagues at IOCB Prague. www.uochb.cz/en/news/811/...
uochb.cz
Pavel Jungwirth, a leading figure in the world of chemistry, has died
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences is deeply saddened to announce that on Thursday 23 July 2026, our outstanding colleague, teacher, mentor and…
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ktr-nakanishi.bsky.social @ktr-nakanishi.bsky.social · 24/07/2026
We're hiring! Join the Nakanishi Lab at The Ohio State University as a Postdoctoral Scholar. Seeking candidates with experience in protein expression/purification (baculovirus or human cells). Cryo-EM experience is a plus. Apply: osu.wd1.myworkdayjobs.com/OSUCareers/j...
osu.wd1.myworkdayjobs.com
Post Doctoral Scholar
Screen reader users may encounter difficulty with this site. For assistance with applying, please contact hr-accessibleapplication@osu.edu. If you have questions while submitting an application, pleas...
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Petr Svoboda @svobodalab.bsky.social · 19/07/2026
Deadline in less than two weeks!
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Jason Rasgon @vectorgen.bsky.social · 22/05/2026
This is fucking insanity www.insidehighered.com/news/quick-t...
insidehighered.com
Report: NIH, NASA Restrict Co-Authoring With Foreign Scientists
The National Institutes of Health and the National Aeronautics and Space Administration are targeting collaborations between U.S. scientists and foreign researchers, Science reports.
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The Cecere Laboratory @cecerelab.bsky.social · 22/05/2026
Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation. rdcu.be/fj8Er #Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu
nature.com
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny - Nature Structural & Molecular Biology
In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression an...
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Petr Svoboda @svobodalab.bsky.social · 22/05/2026
My two PhD students got denied visa to go to the RNA Society meeting in Canada. Each one 2x. No letters from Canadian organizers or me helped. F*ck! Sh*t! I'm angry with this I'm-a-Canadian-government-representative-screw-you-here's-your-generic-f*ck-off-letter.
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Petr Svoboda @svobodalab.bsky.social · 15/04/2026
1/6 This November, the Institute of Molecular Genetics, the leader in vertebrate functional genomics in Czechia, open a call for applications for its Director (starting 1.5. 2027). Whoever would seriously think about it, please, contact me. Thanks for RT. img.cas.cz/en/
img.cas.cz
Institute of Molecular Genetics of the Czech Academy of Sciences
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Petr Svoboda @svobodalab.bsky.social · 22/05/2026
We put together a small review of RNA silencing in mammalian oocytes. It's not comprehensive to cover everything what was published but it focuses on key concepts and features, which I think are sometimes overlooked. febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com
FEBS Press
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI-associated RNA (piRNA) pathway. These pathways use small RNAs to g...
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Petr Svoboda @svobodalab.bsky.social · 15/04/2026
1/6 This November, the Institute of Molecular Genetics, the leader in vertebrate functional genomics in Czechia, open a call for applications for its Director (starting 1.5. 2027). Whoever would seriously think about it, please, contact me. Thanks for RT. img.cas.cz/en/
img.cas.cz
Institute of Molecular Genetics of the Czech Academy of Sciences
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Dina Grohmann @curiousdina.bsky.social · 23/02/2026
If you are looking for “more”, apply for this outstanding PhD program which offers you ample opportunities to develop as a scientist and leader connecting to peers, leaders in the RNA field in Germany, Europe and around the world. Learn the science but also about translation into applications.
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Dominik Handler @86dominik.bsky.social · 13/02/2026
How does the piRNA pathway solve the self vs. non-self problem? 🧬 Since piRNAs come from single-stranded RNA, how does the cell choose the right ones? For years, "piRNA clusters" were seen as THE privileged source. But are they really special and earmarked for biogenesis? (1/19)
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Petr Svoboda @svobodalab.bsky.social · 21/01/2026
Modern surgery is a miracle. And also a funny hourglass concept of dignity. You come with all your dignity and start giving it up until the moment you end up naked & shaved on the operation table and later in the intensive care. And from that moment you start to gain it back.
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Nicholas A. Christakis @nachristakis.bsky.social · 17/11/2025
Yale’s Institute for Foundations of Data Science (FDS) @yaledatascience.bsky.social is seeking applications for postdoctoral positions. These are cool, generously supported, competitive positions, expected to last 2-3 years, for independent scholars working on the foundations of data science.
academicjobsonline.org
Yale University, Institute for the Foundations of Data Science
Job #AJO31114, Postdoc in Foundations of Data Science, Institute for the Foundations of Data Science, Yale University, New Haven, Connecticut, US
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Max Perutz Labs Vienna @maxperutzlabs.ac.at · 05/11/2025
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
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Oded Rechavi @odedrechavi.bsky.social · 06/11/2025
Let's go! Super excited to partner with @richardsever.bsky.social and the fantastic @openrxiv.bsky.social team - Preprints have been the best thing that happened to science publishing during my lifetime, and we're happy @qedscience.bsky.social can make preprints do more 👊
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Susan Gasser @susanmgasser.bsky.social · 25/10/2025
The death of American intellectual and scientific leadership. Not only Harvard does this: Stanford, Brown, Boston U: it’s across all higher education. MADA (dumb again)
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European Research Council (ERC) @erc.europa.eu · 25/10/2025
Seeking work in a research group run by an ERC-funded researcher? You can find more than 145 positions open for application on the #Euraxess website 👉 buff.ly/ROwXHf6 #ChooseEurope #jobs #research
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Dr. Rod Taylor @fossilrod.bsky.social · 24/10/2025
This #fossilfriday, we move in time to the #Permian when the #amphibian Seymouria sanjuanensis lived in what is New Mexico today. Clusters of large animals like this one are rarely found in the #fossil record, especially this well preserved. Photo: Amy Henrici
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Neil Shubin @neilshubin.bsky.social · 24/10/2025
Catch my new lecture at the Collège de France entitled “The Origin of Walking.” Thanks to @denisduboule.bsky.social for hosting! 💙🧪 m.youtube.com/watch?v=fNim...
m.youtube.com
Neil Shubin (2) - Denis Duboule (2025-2026)
YouTube video by Sciences de la vie - Collège de France
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paveltomancak.bsky.social @paveltomancak.bsky.social · 24/10/2025
@odedrechavi.bsky.social heresy comes to the cradle of #Genetics #Brno @ceitec.eu
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Petr Svoboda @svobodalab.bsky.social · 23/10/2025
OMFG, Zima chce jako 1. prioritu zvysit pocet ERC o polovinu 😂 (smich skrz slzy). Kolik ERCs opustilo PrF kvuli tomu, ze tam stestim nemohli vydrzet za jeho dekanovani? Jaka systemova opatreni udelala jeho PrF pro ERC zadatele? Od administrativni podpory po mentoring? [repost vlakna z twitteru]
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Petr Svoboda @svobodalab.bsky.social · 23/10/2025
Four months later, back at the crime scene. 😆 #TCTeAC
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Piali Sengupta @senguptalab.bsky.social · 23/10/2025
TT faculty job opening in #Neuroscience! We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply academicjobsonline.org/ajo/jobs/30961
academicjobsonline.org
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
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The Fromm Lab @frommlab.bsky.social · 21/10/2025
🔥🔥🔥🔥New paper out; a opinion piece in @narjournal.bsky.social with Michael Hackenberg, @panosbino.bsky.social, Kevin K Peterson and @marcfriedlander.bsky.social 🔥🔥🔥🔥 „Knowing is not enough, we must apply“ academic.oup.com/nar/article/...
media.tenor.com
a statue of a man 's head with a bunch of paper coming out of it
ALT: a statue of a man 's head with a bunch of paper coming out of it
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Oded Rechavi @odedrechavi.bsky.social · 21/10/2025
Unlike the heart attack of getting a “Decision” email, it’s such a good feeling to get a “Your review is ready” email from qed :)
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Petr Svoboda @svobodalab.bsky.social · 04/10/2025
... if anyone would have extra 300 bucks and would speak french and be a true nerd ... here is a hidden gem awaiting to be found: www.ebay.com/itm/40524050...
ebay.com
Pardon Our Interruption...
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Biozentrum, University of Basel @biozentrum.unibas.ch · 29/09/2025
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging www.biozentrum.unibas.ch/open-positio... #biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
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IOCB Prague @iocbprague.bsky.social · 11/09/2025
✍️ We are seeking a highly motivated technician to join our multidisciplinary team. See more ► www.uochb.cz/en/open-posi... ⤵️ #openposition #iocbprague #iocb #researchjobs #biosciences
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ME Torres-Padilla @metorrespadilla.bsky.social · 12/06/2025
Are you @ the late stages of your postdoc ? Want to pursue a PI career ? Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum www.helmholtz-munich.de/en/stem-cell... Peer-networking / Career orientation and more !!! Please distribute :) 🙂
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Elin Videvall @elinvidevall.bsky.social · 01/09/2025
Anyone with experience doing #metagenomics #microbiome of small insects, e.g. mosquitoes? 🦟🦠 Trying to figure out feasibility of doing individual metagenomes vs pools of individuals. I see both approaches are still used in the literature. My concern would be getting enough DNA from individuals.
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Dr. Julie Claycomb @farmgirlphd.bsky.social · 29/08/2025
Kicking off our third day of #argonautes2025 with a talk by Nobel Prize winner and all around amazing person, scientist, and mentor, Victor Ambros! 🐙
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Petr Svoboda @svobodalab.bsky.social · 28/08/2025
The Argonautes 2025 - we made a special gift for participants - a card set with 32 different Argonautes + an extension pack with four Nobel prize winners from the small RNA field. Mello, Fire, Ambros & Ruvkun as jokers :-) #argonautes2025
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Ian in 314, MPH @ianwrobel.bsky.social · 25/08/2025
I thought this was way cool. It’s a fire hydrant painted in Starry Night by Van Gogh in Kirkwood.
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Petr Svoboda @svobodalab.bsky.social · 21/08/2025
When a beetle crawls over the surface of a globe, it doesn't notice that the track it has covered is curved ...
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Petr Svoboda @svobodalab.bsky.social · 21/08/2025
Argonautes are coming :-) ... soon at @imgprague.bsky.social ... finishing preparations. Still missing a few things like drums, guitar, badges, beer ... but it's under control. I think. I hope. :-)) #argonautes2025
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James Galbraith @gulbruth.bsky.social · 19/08/2025
Does selfing allow or even lead to massive genome reshuffling, expansion and sky high homozygousity? Come and find out at posters 29 and 42 this afternoon, only at #eseb2025 and learn about an organism whose genome looks like it went through a blender and came out high repetitive and homozygous.
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Denis Wirtz @deniswirtz.bsky.social · 10/08/2025
My team has updated our free database of POSTDOC fellowships. This database contains 286 entries. For each entry, we provide a link, short description, deadline, amount, and eligibility criteria. Download this updated and expanded database here: research.jhu.edu/rdt/funding-...
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Petr Svoboda @svobodalab.bsky.social · 07/08/2025
Disaster strikes today. Czechia is mourning.
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A. Sánchez Alvarado @planaria1.bsky.social · 06/08/2025
Evolution’s eye game is wild, but mollusks take it to another level CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates rdcu.be/ezw0t
url.us.m.mimecastprotect.com
A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
Nature Communications - Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these...
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Petr Svoboda @svobodalab.bsky.social · 31/07/2025
#TCTeAC !
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Oded Rechavi @odedrechavi.bsky.social · 31/07/2025
I'm saving this picture to show my grandkids
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Itai Yanai @itaiyanai.bsky.social · 29/07/2025
🚀 Today we're launching the 'Night Science Institute', a non-for-profit organization to lead a cultural shift in science! You may say we're dreamers 😉, but we think we're not the only ones. Perhaps today you will join us to make the Day Science and Night Science parts of the process live as one!
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