Most of my students use AI, and I worry about its corrosive effects. We must not entrust tech companies with our long-term health, says Prof Devi Sridhar, chair of global public health at the University of Edinburgh

I’d benefit if AI cured cancer. And I still want AI progress to slow down.

Nucleosomes with their associated modifications organize and regulate the genome. It is unclear how this is integrated with the requirement of replica…

Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...

The design of RNA-guided nucleases with properties not limited by evolution can expand programmable genome-editing capabilities. However, generating diverse multidomain proteins with robust enzymatic ...

Several anti-cancer drugs delay transcription termination, triggering transcriptional readthrough. Readthrough has long been considered an incidental transcriptional byproduct, however a recent study ...

Cellular stresses regulate transcriptional readthrough, whereby RNA polymerase II elongates past a gene's polyadenylation cleavage site without RNA cleavage. Readthrough has been reported in several c...

Elon Musk’s empire of wealth is built on suffering.

Editorial: The economic fallout of the US-Israeli assault and Tehran’s retaliation is spreading fast, and pushing the most vulnerable towards disaster

Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...

A tiny self-copying molecule offers the clearest answer yet to the mystery of the origins of biology, reports Science Director Roger Highfield.

The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

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Failed supernova candidate points to a stealthy pathway of stellar collapse

She made key contributions to US cold-war science despite facing huge barriers as a Black woman.