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Molly Gale (Gale-Hammell Lab)

@mollygale.bsky.social
740 followers 434 following 49 posts

Jumping Genomics! I run a lab in NYC that studies transposons 🧬in the brain 🧠 Opinions are all mine mghlab.org

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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 26/08/2026
📣 Heads up! 📣 Estradiol treatment is linked to reduced risk of cardiovascular disorders, neurodegenerative disease, and certain cancers. There’s been a shortage for over a year with no moves by the FDA to declare a shortage Please sign a Change.org to fix it! www.change.org/p/ask-the-fd...
change.org
Sign the Petition
Ask the FDA to declare an estrogen patch shortage
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 20/08/2026
📣 Postdoc opportunity studying ncRNAs in the brain! Great lab in NYC - Check it out! #RNAsky
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Reposted by Molly Gale (Gale-Hammell Lab)
Natalia Sampaio @drnatsampaio.bsky.social · 11/08/2026
We set out to map what #RNA binds to immune receptor #MDA5 during #virus infection. Our findings were unexpected: rather than viral, it was host RNA! Excited (translate: frankly, knackered) to share our paper in @natureportfolio.nature.com Nature Immunology! 🔗 www.nature.com/articles/s41... 🧵👇
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Cedric Feschotte @cedricfeschotte.bsky.social · 29/05/2026
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com
thefeschottelabatcornell.com
The Feschotte Lab at Cornell
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 07/05/2026
Just sat through a roundtable on AI where they opened with- “Do you think it’s a good thing or a bad thing that AI is surpassing human intelligence” and I just. Wow. My questioning of the premise was met with some weird comments that we might need “co-scientists” in the loop. “Co-scientists”??
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 17/04/2026
Protein-templated DNA synthesis??
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Tressie McMillan Cottom @tressiemcphd.bsky.social · 17/04/2026
Neko Case has written the lyrics AND script for stage version of Thelma & Louise.
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 10/01/2026
📣Excited to announce a new pre-print from the lab 📣 Led by my student @storiesofisobel.bsky.social in collab with Hemali Phatnani @nygenome.org We discovered a novel class of TDP-43 dependent cryptic gene-TE spliced transcripts: crypTEs #TEsky #RNAsky #ALS doi.org/10.64898/2026.01.09.698641
doi.org
TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues
TDP-43 is an RNA and DNA binding protein that plays major roles in regulating RNA processing. In particular, TDP-43 dysfunction leads to the accumulation of cryptic splice isoforms that result from im...
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Reposted by Molly Gale (Gale-Hammell Lab)
Priya Prakash @pryprk.bsky.social · 01/12/2025
I was featured on The Scientist as a part of their 'Postdoc Portraits' series where I spoke about my scientific career path and ongoing work on oligodendrocyte dysfunction in neurodegeneration. Check it out! www.the-scientist.com/postdoc-port...
the-scientist.com
Postdoc Portrait: Priya Prakash
This postdoc uncovers how glial dysfunction drives neurodegeneration in a rare movement disorder.
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Reposted by Molly Gale (Gale-Hammell Lab)
NY-CURES @nycures.bsky.social · 24/11/2025
📢 SIGN & SHARE THE PETITION! 📢 New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
c.org
Sign the Petition
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 08/11/2025
I was still faculty at CSHL when Watson’s remaining titles were stripped in 2018. Duncan Watson wrote a sad/angry email to everyone living on Bungtown road. Me included. He told us we were no longer allowed to use the too “intimate” name Jim The psychology of descendants of famous men fascinates me
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Reposted by Molly Gale (Gale-Hammell Lab)
Alexandra Whiteley @alexwhiteley.bsky.social · 23/10/2025
I'm so excited to see this Perspective with @jasonsynaptic.bsky.social out in Neuron! About 8% of our genome is made up of the remnants of LTR-containing retroelements - here, Jason and I explore the activities of retroTEs in neurological health and disease! authors.elsevier.com/c/1lzTx3BtfH...
authors.elsevier.com
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 08/11/2025
Of all the hot takes on Rosalind Franklin, I'm truly baffled by the argument that acknowledging harm done to women somehow removes their agency. And thus, it's more "feminist" to pretend that women were not wronged by the men who tormented and harassed them
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500 Women Scientists @500womensci.bsky.social · 04/11/2025
VOTE! VOTE! VOTE! VOTE! VOTE!
media.tenor.com
a kermit the frog is holding a sign that says vote .
Alt: a kermit the frog is holding a sign that says vote .
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BK. Titanji @boghuma.bsky.social · 25/10/2025
Finally read the paper and it's worth the buzz. mRNA vaccines saved 20 million lives in a global pandemic and the technology is opening up new avenues for the treatment of deadly cancers. This is really one of the most impactful scientific developments of our time. www.nature.com/articles/s41...
nature.com
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
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Reposted by Molly Gale (Gale-Hammell Lab)
Emma Harding @emma-harding.bsky.social · 27/09/2025
Do you research endogenous retroviruses (ERVs) or want to learn more about them? 🧬🤔 Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️ Abstracts due 1st October! events.humanitix.com/aussierv-2025 #ERV #retrovirus
events.humanitix.com
AussiERV 2025
AussiERV: Australia’s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!
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Conrad Hackett @conradhackett.bsky.social · 04/09/2025
Disease prevalence in US states before & after vaccine introduction 🧪 From Edward Tufte & graphics.wsj.com/infectious-d...
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Charles Jennings @chasjennings.bsky.social · 04/09/2025
Filmmaker Pamela Green is planning a movie about the late Ben Barres, transgender neuroscientist, world expert on glial cells, and an inspirational advocate for women and minorities in science. Pamela is seeking funds to finish her research and script – see fundraising trailer below.
askthequestionmovie.com
AskTheQuestionMovie.com – An inspiring portrait of a rebel scientist with boundless curiosity, who, despit
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Shane Liddelow @liddelowsa.bsky.social · 15/08/2025
are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social? LAST WEEK TO APPLY to be a SPiNES speaker for our next season. Details and apply here: med.nyu.edu/departments-... COME AND WOW US!
media.tenor.com
a black and white photo of a crowd of people standing and sitting in chairs .
ALT: a black and white photo of a crowd of people standing and sitting in chairs .
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Reposted by Molly Gale (Gale-Hammell Lab)
Mark Peifer (He, him) @peiferlabunc.bsky.social · 02/07/2025
For ESIs dealing with grants being rescinded: if an investigator’s 1st substantial independent research award is terminated within the first 3 years of the project period (not due to scientific misconduct ) they can request the reinstatement of ESI status grants.nih.gov/news-events/...
My First Substantial Independent Research Award Was Terminated Early. Can My ESI Status Be Reinstated?
June 12, 2025
Investigators lose their Early Stage Investigator (ESI) eligibility when they successfully compete for and receive a substantial independent research award. In the event an investigator’s first substantial independent research award is terminated within the first three years of the project period, and this was not due to scientific misconduct or other disqualifying events, the investigator can request the reinstatement of ESI status, using the ESI Extensions request tool in eRA commons. See Requesting an Extension for instructions.

For more, see the Early Stage Investigators FAQ page.
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MwahahahahahadScientist @mads100tist.bsky.social · 27/06/2025
TIL that one of the books removed from the Armed Forces Library because it "had DEI" in it is Ben Barres' autobiography. Remember that you can buy and should read this book because Ben was badass and an amazing scientist mitpress.mit.edu/978026253954...
The cover of the book, in greenish blueish color. The title is "The autobiography of a transgender scientist" by one of the most badass human beings that have ever existed, Ben Barres
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Reposted by Molly Gale (Gale-Hammell Lab)
Dana Foundation @danafoundation.bsky.social · 23/06/2025
Tomorrow, 6/24, NINDS is celebrating 75 years with a special congressional briefing spotlighting scientific advancements made possible from #NINDS over the past 75 years—from foundational discoveries in brain function to life-changing therapies for neurological diseases. #neurosociety #brainresearch
docs.google.com
Celebrating 75 Years of Scientific Discovery and Innovation: NINDS 75th Anniversary Congressional Neuroscience Caucus Briefing & Reception
Event Timing: Tuesday, June 24, 2025 - 3:30-5:00pm ET Event Address: Longworth House Office Building Room 1539, Capitol Hill, Washington, DC Snacks and refreshments will be provided
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NSF–DOE Rubin Observatory @rubinobservatory.org · 23/06/2025
The image offers a stunning variety of objects — from bright stars ranging from blue to red in color, to nearby blue spiral galaxies, to distant red galaxy groups — demonstrating the broad range of science made possible by Rubin data ✨🔭🧪
A sprawling, textured field of galaxies scattered across the deep black of space. It is filled with the delicate smudges and glowing cores of galaxies of many shapes, sizes and colors, as well as the bright multi-colored points of stars. To the lower left is a region filled with the hundreds of golden glittering gems of a distant galaxy cluster. In the foreground, below and right of center, two blue spiral galaxies look like eyes beneath the entangled mass of a triple galaxy merger in the upper right. A few bright blue points of foreground stars pierce the glittering tapestry.

Throughout the image, thousands of galaxies gather in clusters or are spread throughout, like glittering gems strewn on a table. Some are sharp-edged and spiral, like coiled ribbons; others round and diffuse, like polished pebbles. Still others are just smudges of various colors. The background is peppered with pinpoint stars in reds, yellows, and blues, crisp against the velvet black.
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Reposted by Molly Gale (Gale-Hammell Lab)
phoeberice.bsky.social @phoeberice.bsky.social · 18/06/2025
Dear Mobile DNA Researchers, The 8th Woods Hole Mobile Genetic Elements meeting will be held Aug 28 to Aug 30, 2025, at the MBL in Woods Hole, Massachusetts. Info, registration, and abstract submission: www.eventsquid.com/event/28372 #MobileDNA #MobileGeneticElements
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 16/06/2025
🧬🌽 Happy Transposon Day! 🌽🧬 Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Barbara McClintock portrait
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Reposted by Molly Gale (Gale-Hammell Lab)
Lisa's Legacy for ALS @lisalegacy4als.bsky.social · 10/06/2025
We hate that this t-shirt has to exist but we love the creativity behind it. Our friend Ed created it as he works to bring about change for all battling ALS. Now please follow the alien's request and complete an ALS Clinic Survey today. bit.ly/448GkkF
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Liz Haswell @ehaswell.bsky.social · 09/06/2025
*URGENT* please support NIH research and the NIH employees who are standing up for science at the risk of losing their jobs! Sign *TODAY* in support of the Bethesda Declaration. The senate appropriations committee is reviewing the NIH budget Tuesday at 10 am. SHARE widely! 🧪
actionnetwork.org
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
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Katie Mack @astrokatie.com · 03/06/2025
If you burn down a forest, you don't miss out on lumber for just that season. You have to replant all the trees, nurture them, and wait for them to grow. The science and research budget cuts happening now are wanton, senseless arson. Recovery, if it ever happens, will take generations.
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Reposted by Molly Gale (Gale-Hammell Lab)
SalehLab @salehlabparis.bsky.social · 20/05/2025
Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization! Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/... Congrats to all the authors and thanks to reviewers and editor!
science.org
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila
Hsc70-4 localizes to the cell surface of Drosophila cells, binds to exogenous dsRNA, and mediates its internalization.
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Reposted by Molly Gale (Gale-Hammell Lab)
Ammar Al-Chalabi @ammaralchalabi.bsky.social · 10/05/2025
Our paper describing the results of the MIROCALS trial of low-dose interleukin-2 in #ALS #MND is out in the Lancet @thelancet.bsky.social Open access Read it here: www.thelancet.com/journals/lan...
thelancet.com
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial
With this treatment schedule, IL-2LD resulted in a non-significant reduction in mortality in the primary unadjusted analysis. However, the difference between the results of unadjusted and adjusted ana...
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Reposted by Molly Gale (Gale-Hammell Lab)
Tom Ellis @proftomellis.bsky.social · 02/05/2025
My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...
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Whitney Gibbs @whitgibbs.bsky.social · 30/04/2025
My lab at NYU is hiring a postdoc interested in RNA biology and local translation in neurons following axonal injury/neurodegenerative diseases!! Apply here: apply.interfolio.com/165681
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Reposted by Molly Gale (Gale-Hammell Lab)
Andreas Prokop @poppi62.bsky.social · 10/04/2025
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
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Jordan Meier @doc-jlmeier.bsky.social · 10/04/2025
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost. www.training.nih.gov/research-tra...
training.nih.gov
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Deborah Bourc’his @deborahbourchis.bsky.social · 02/04/2025
Do you have transposon-related research cooking, with some cool results you are exciting to share? Start thinking about registering to #EMBOMobileGenome workshop! Nov 4-7 2025 in Heidelberg. One of the historical TE meetings, with a diverse and welcoming community. www.embl.org/about/info/c... 1/3
embl.org
The mobile genome: genetic and physiological impacts of transposable elements
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Dementia Researcher @dementiaresearcher.bsky.social · 02/04/2025
Associate / Senior Research Associate in TORUS Deployment Study (University of Bristol) - new sensing technologies to support people with Parkinson's Disease participating in research. Closing date: 22nd April www.dementiaresearcher.nihr.ac.uk/job/senior-r...
dementiaresearcher.nihr.ac.uk
Senior Research Associate: TORUS Deployment Study
Associate / Senior Research Associate in TORUS Deployment Study (University of Bristol) - new sensing technologies to support people with Parkinson's Disease participating in research.
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Reposted by Molly Gale (Gale-Hammell Lab)
Dementia Researcher @dementiaresearcher.bsky.social · 02/04/2025
The Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) is seeking an experienced cell/molecular Postdoctoral Research Scientist with an interest in neuroinflammation. Closing date: 28th April www.dementiaresearcher.nihr.ac.uk/job/postdoct...
dementiaresearcher.nihr.ac.uk
Postdoctoral Research Scientist: Neuroinflammation
The Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) is seeking an experienced cell/molecular Postdoctoral Research Scientist with an interest in neuroinflammation.
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Reposted by Molly Gale (Gale-Hammell Lab)
Jackie Gio @jackiegio.bsky.social · 28/03/2025
Our department is hiring! Huge endorse! www.nature.com/naturecareer...
nature.com
Tenure Track Faculty Opportunity at Renowned Research Center in Philadelphia! - Philadelphia, Pennsylvania (US) job with Temple University | 12838286
Tenure Track Faculty Opportunity at Renowned Research Center in Philadelphia! Center for Substance Abuse Research (CSAR) Lewis Katz School of Medic...
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Rita Rebollo @ritarebollo.bsky.social · 27/03/2025
Hi! Here is a PhD opportunity at Montpellier, IGH institute with Séverine Chambeyron to study endogenous retroviruses ! #TEsky #PhD
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ASAP Team Jakobsson @jakobssonasap.bsky.social · 18/03/2025
Last week, some of us from Team Jakobsson had a great time in Arizona at the 2025 CRN Collaborative Meeting! Plenty of insightful talks and networking. Shoutout to @kirkebylab.bsky.social for a fantastic talk on PSC-based therapies and models of PD 🌟🧬🏜️ #CRNPhoenix2025 @asapresearch.bsky.social
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Reposted by Molly Gale (Gale-Hammell Lab)
Matt Sikora @mjsikora.bsky.social · 15/03/2025
Still wrapping my head around 57% cut to CDMRP (cdmrp.health.mil) funding in CR. CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates. BEFORE the cut, the breast cancer program funded 3-5% of proposals. What now?
cdmrp.health.mil
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 10/03/2025
Super happy to announce the latest work from my lab together with Hemali Phatnani @nygenome.org & NYGC ALS Consortium! We've combined ALS patient profiling (100s!), ML classifiers and matched bulk/single-cell data to dive into ALS Molecular Subtypes #NIHfundedResearch www.cell.com/cell-reports...
cell.com
ALS molecular subtypes are a combination of cellular and pathological features learned by deep multiomics classifiers
O’Neill et al. present a deep exploration of molecular subtypes in ALS postmortem tissues from the NYGC ALS Consortium. Matched bulk and single-cell profiles demonstrate that ALS subtypes are a combin...
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 16/01/2025
I'm excited to be taking part in the ALS Expert Talk Series happening next week: Jan 22 at 7pm ET. I'll be presenting my lab's latest research into ALS molecular subtypes - what are subtypes and what can they tell us about ALS? #EndALS #EverythingALS #ALS 🔔Register: everythingals.org/events
EverythingALS.org/events
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Rebecca Berrens @rberrens.bsky.social · 16/01/2025
Very excited to share our work with the QMUL Epigenetics hub and everyone else that is interested to join online and learn what the lab has been up to with regard to #transposons #longreads #nanopore and #singlecells
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Reposted by Molly Gale (Gale-Hammell Lab)
Michelle Percharde @mpercharde.bsky.social · 26/11/2024
Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)
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Sergiu P. Pasca @sergiuppasca.bsky.social · 21/11/2024
Applications are open for our Stanford Brain Organogenesis course in 2025! This has gotten more and more competitive and we generally get many hundreds of applications for the 20 or so spots. Please note that the committee gives a lot of attention to the motivation letter!
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Reposted by Molly Gale (Gale-Hammell Lab)
Denis Wirtz @deniswirtz.bsky.social · 19/11/2024
Check out our updated database of 189 PhD fellowships and funding opportunities. For each fellowship, we provide a description, $ amount, deadline, link to funder and eligibility criteria (such as citizenship). Good luck! Download freely here: research.jhu.edu/rdt/funding-...
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Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 18/11/2024
Tracking transposable element (TE) activity in genomics data can be a pain, but there are solutions! Our lab built TEtranscripts -- which we've updated to work for small RNAs (TEsmall), bulk RNA at the locus level (TElocal), and in single-cell data (TEsingle). Check it out! www.mghlab.org/software
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