📣 New preprint 📣
Excited to share our latest work, which I helped lead, identifying a new class of TDP-43 dependent cryptic gene-TE spliced transcripts (crypTEs) in induced neurons and ALS patients.
🔍 Actively searching for postdoc & industry research roles.
doi.org/10.64898/2026.01.09.698641
doi.org
TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues
TDP-43 is an RNA and DNA binding protein that plays major roles in regulating RNA processing. In particular, TDP-43 dysfunction leads to the accumulation of cryptic splice isoforms that result from im...