Reposted by Maud BorenszteinJean Léon Maître @maitrejl.bsky.social · 06/10/2026📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr 16872
Maud Borensztein @maudborensztein.bsky.social · 04/08/2026Dampening is seen at day 6, but XCI initiates from day 10–12, and is not yet complete (Zhou et al, F.Tang lab). Your model implies late replication is an early XCI event in human too to coincide with L1 expression. Maybe a short window of time also helps limit insertions? Really interesting, thanks! 020
Maud Borensztein @maudborensztein.bsky.social · 03/08/2026Really cool study! Curious how this fits with the still-open question of when an heterochromatic Xi actually forms in human embryos (vs dampening of both active Xs in early blastocysts). Any thoughts on whether the late-replication landscape is already present at human peri-implantation stage? 100
Reposted by Maud BorenszteinGeoff Faulkner @faulknerlab.bsky.social · 30/07/2026Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie... 58136
Reposted by Maud BorenszteinGael Cristofari @retrogenomics.bsky.social · 30/07/2026That’s a beautiful story that shows again how powerful long reads are for studying transposable elements. Exciting times! For accessing the Perspective piece without a paywall: www.science.org/eprint/NIKHD...science.orgWhy the X chromosome is rich in L1 mobile elementsPreferential insertion into the late-replicating inactive X explains L1 accumulation in this chromosome 1248
Reposted by Maud BorenszteinDarío Lupiáñez @dariloops.bsky.social · 21/07/2026🚨 Job Alert - Please share 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! ✅ 4 years fully funded PhD position 💻🧪 Experimental or computational backgrounds welcome 👇 Details below #PhDPosition #PhDOpportunity #AcademicJobs 03642
Reposted by Maud BorenszteinGrand Lab @grandlab.bsky.social · 07/05/2026Excited to share our first story led by @martinacapriati.bsky.social! How do cells control the expression of viability genes? We find that single transcription factors can drive both chromatin opening and gene activation from densely co-bound CpG island promoters, including at essential genes 25127
Reposted by Maud BorenszteinMaxim Greenberg @maxvcg.bsky.social · 06/07/2026I had an (honestly) really fun time writing up an "In Preprints" piece on the two fantastic studies from @grandlab.bsky.social and @schubelerlab.bsky.social. Check it out here. I have also put the original threads from the authors below. journals.biologists.com/dev/article/...journals.biologists.comIn preprints – housekeeping the housekeeping genesThe term ‘housekeeping gene’ evokes a sense of banality. These are the boring genes that hum in the background, impervious to cell state or stress. For a developmental biologist captivated by the impa... 23613
Reposted by Maud BorenszteinDeborah Bourc’his @deborahbourchis.bsky.social · 27/06/2026Coupes drastiques du budget de la recherche + durcissement des règles d’attribution des financements ANR «Allez à l’ERC!» qu’ils disent, mais l’ERC saturée prend des mesures pour limiter les candidatures #deadend#recherchefrançaise Une petition semble vaine mais il faut commencer quelque part 👉 01915
Reposted by Maud BorenszteinElphege Nora Lab at UCSF @elphegenoralab.bsky.social · 13/05/2026Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇 2197112
Reposted by Maud BorenszteinOded Rechavi @odedrechavi.bsky.social · 05/05/2026We built an AI that will tell you what will get your grant rejected. It’s a tough critique, but it’s better to know when you can still do something about it 👇 @qedscience.bsky.social 54510
Reposted by Maud BorenszteinMichael Rera @michaelrera.bsky.social · 27/04/2026You want to design a very specific single AA mutation for CRISPR editing or interpret your newly identified natural polymorphism? This is for you 👇 with a user-friendly web tool, thanks to the PhD work of @abakamarina.bsky.social www.nature.com/articles/s41... shorturl.at/pFAZ7 shorturl.at/ogXb6linkedin.comProteome-wide prediction of the functional impact of missense variants with ProteoCastYou just identified a new mutations in your favourite but don't know whether it's functional Marina Abakarova 's PhD project, with the help of Maria Ines Freiberger Arnaud Liehrmann, and under the sup... 1195
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 17/04/2026🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social 📅 1 May–15 June 2026 📩 search2026@igmm.cnrs.fr 📎Full information 👇 #LifeScience #MolecularBiology #Research #PI #CNRS 12428
Reposted by Maud BorenszteinPeter Andersen @germline.bsky.social · 17/04/2026Reminder: PhD position in my lab is open for two more weeks. How do germ cells use their own private transcription factors? Come help us find out. Fully funded. Deadline May 1. Flyer attached — please boost! 🙏 01226
Reposted by Maud BorenszteinDiana Pinheiro @dianapinheiro.bsky.social · 30/03/2026👇👇👇 If are you excited about helping us recruit and train the next generation of scientists, don't hesitate to apply! The @viennabiocenter.bsky.social is a great place to work. 🙂 095
Maud Borensztein @maudborensztein.bsky.social · 30/03/2026Yolanda and I enjoyed writing this review on X-chromosome reprogramming in the mammalian germline. 👇 Hope you'll enjoy reading it too! @biochemsoc.bsky.social #epigenetic #germline #XCI @igmm-montpel.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social 084
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 09/03/2026🦠 Quand un virus devient cheval de Troie 🔬 Cette découverte éclaire la transmission et l’évolution des deltavirus. 👉 www.insb.cnrs.fr/fr/cnrsinfo/... 👏 @karimaj.bsky.social @viroscope.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social #IGMM #CNRS #Virologie #Rechercheinsb.cnrs.frQuand un virus en transporte un autre : le « cheval de Troie » des deltavirusCertains virus minuscules, appelés deltavirus, ne peuvent se propager qu’en s’appuyant sur d’autres virus. 063
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 23/03/2026Save the date : Seminar by Kristina Zumer on Tuesday 24th March at 11h @uni-goettingen.de 022
Reposted by Maud BorenszteinJamie Hackett @jamiehackett.bsky.social · 05/01/2026This went under the radar but answers a fundamental question in Epigenetics... From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How? Outstanding work from Mathieu Boulard and colleagues www.biorxiv.org/content/10.6...biorxiv.orgThe transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancersThe ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo... 112943
Reposted by Maud Borenszteinheardlab.bsky.social @heardlab.bsky.social · 15/12/2025💡 New paper out in @natcellbio.nature.com 💥💥💥🚀🚀🚀 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation well beyond early development, in differentiated, non-dividing cells and in vivo post implantation embryos 👇👇👇👇 1369
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 18/11/2025This is today ! 021
Maud Borensztein @maudborensztein.bsky.social · 12/11/2025We are thrilled to host Elphège Nora next week in Montpellier 🤩 ☀️🧬 @elphegenoralab.bsky.social @cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social #transcription 062
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 07/11/2025🧬Le magazine de la Métropole de Montpellier consacre un article à Jamal Tazi, pour son rôle dans la découverte de l’Obefazimod (ABX464), molécule issue de la recherche académique et développée grâce à une collaboration public-privé exemplaire. encommun.montpellier.fr/sites/defaul...encommun.montpellier.fr 032
Reposted by Maud Borenszteindandergassen.bsky.social @dandergassen.bsky.social · 11/11/2025New paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡 Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids. 11510
Reposted by Maud BorenszteinMaxim Greenberg @maxvcg.bsky.social · 28/10/2025Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly! 13651
Reposted by Maud BorenszteinOded Rechavi @odedrechavi.bsky.social · 15/10/2025BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇) 56494184
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 13/10/2025@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍. 👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus” www.the-scientist.com/boa-constric...the-scientist.comBoa Constrictor Brain Cells Slither into FocusFrom reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton. 097
Reposted by Maud BorenszteinNaomi Moris @nmoris.bsky.social · 09/10/2025The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍 24028
Reposted by Maud BorenszteinDevelopment @dev-journal.bsky.social · 09/10/2025An Interview with Azim Surani Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia: journals.biologists.com/dev/article/... 01712
Reposted by Maud BorenszteinEdda Schulz @eddaschulz.bsky.social · 06/10/2025⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation. 👉 We discover how sex and development signals are decoded at a single gene locus. www.nature.com/articles/s41... 👇 Bluetorialnature.comReporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular BiologyHere Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation. 311050
Reposted by Maud BorenszteinKara McKinley @karalmckinley.bsky.social · 25/08/2025Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT! 02331
Reposted by Maud BorenszteinEMBO Reports @emboreports.org · 07/08/2025DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation. -> www.embopress.org/doi/full/10.... 0126
Reposted by Maud BorenszteinMounia Lagha @laghalab.bsky.social · 28/07/2025#jobAlert We are hiring! If you like #imaging ,gene regulation and a dynamic group please apply. We are looking for a research assistant with a master degree and prior experience in academia. 02724
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 28/07/2025🚀 @hfspo.bsky.social funded Postdoc 3-year contract Start after Dec 2025 📩 Apply: mounia.lagha@igmm.cnrs.fr Subject: "[HFSP Post doc application]" 📎 CV + short research summary + cover letter 🔗 More info: euraxess.ec.europa.eu/jobs/363437 @laghalab.bsky.social @umontpellier.bsky.social @cnrs.freuraxess.ec.europa.euA PhD in biology, biophysics or a closely related field is required by the start of the appointment. Interdisciplinary profiles are strongly encouraged to apply.- work environment: 054
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 28/07/2025 🎯 Hiring: Biology Research Assistant (M/F) Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social 6-month contract, renewable up to 2 years. Start Sept 15, 2025 | Apply by Aug 11 🔗 emploi.cnrs.fr/Offres/CDD/U... #Hiring #Biology #Research #IGMMemploi.cnrs.fr Portail Emploi CNRS - Offre d'emploi - Assistant ingénieur en biologie (H/F) 033
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 25/07/2025🧬 Avancée majeure issue d’Abivax et de l’équipe Tazi @igmm-montpel.bsky.social @cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH. 📈 +520 % en bourse @lemonde.fr 173
Reposted by Maud BorenszteinBIOLuM Montpellier @biolum-montpellier.bsky.social · 25/07/2025Fantastique !!! 011
Reposted by Maud BorenszteinAndrau Lab @andraulab.bsky.social · 22/07/2025Two major events today on our campus! 🚴♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social! 🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com! 4256
Reposted by Maud BorenszteinMichael Rera @michaelrera.bsky.social · 23/07/202560 days to go for applying to marie-sklodowska-curie-actions.ec.europa.eu/actions/post... if you want to join me to study ageing with an interesting new angle! #Smurfs #2PACmarie-sklodowska-curie-actions.ec.europa.euPostdoctoral FellowshipsThe information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them. 025
Reposted by Maud BorenszteinArnau Sebé-Pedrós @arnausebe.bsky.social · 15/07/2025We are looking for a student to continue our work on chromatin evolution: www.nature.com/articles/s41... www.biorxiv.org/content/10.1... The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes. More info: recruitment.crg.eu/content/jobs... 02838
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 07/07/2025Congratulations to the Carnesecchi lab 🍾🍾 Read below to learn more about their research 👇 031
Reposted by Maud BorenszteinClaire Rougeulle @crougeulle.bsky.social · 18/06/2025Join us in the #institutcurie exceptional environment to explore the mysteries of X chromosome regulation in early human development 024
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 06/06/2025Save the date : Seminar Elphège NORA - June 19h - 11am @elphegenoralab.bsky.social 021
Reposted by Maud BorenszteinEuropean Research Council (ERC) @erc.europa.eu · 02/06/2025Planning to apply for #research #funding from the ERC? From the next application rounds, expect changes to the: • proposal structure • evaluation process • extra funding you can request • eligibility for Starting & Consolidator #Grants (from 2027) More 👇 europa.eu/!RPHWvveuropa.euChanges to the 2026 and 2027 Work ProgrammesWith the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai... 3146102
Maud Borensztein @maudborensztein.bsky.social · 28/05/2025We are recruiting at @igmm-montpel.bsky.social Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩🔬👨🔬☀️ For questions, feel free to write to search2025@igmm.cnrs.fr or DM me! 025
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 28/05/2025📣 We are recruiting new group leaders in Innovative Biology! RNA biology Epigenetic regulation Cell cycle regulation Cancer, immunology Virology Application and information ⬇️ application.igmm.cnrs.fr @cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social 33753
Reposted by Maud BorenszteinIGMM-Montpellier @igmm-montpel.bsky.social · 19/05/2025📢 Mobilité NOEMI CNRS – Ingénieur·e en biologie (BAP A) 🧬 IGMM Montpellier recrute pour projets levure/cellules humaines + plateforme de purification de protéines. 📬 Plus d’infos emploi.cnrs.fr/Offres/MOBIN... @domlibri.bsky.social @oporrua.bsky.social @cnrsbiologie.bsky.socialemploi.cnrs.fr Portail Emploi CNRS - Offre d'emploi - Ingénieur-e en expérimentation et instrumentation biologiques H/F 022