NEW PREPRINT FROM THE LAB IS OUT — DON’T MISS IT!
www.biorxiv.org/content/10.6...
We asked whether the 3D architecture of the inactive X - and in particular CTCF and cohesin - is what keeps escapee genes active.
Spoiler: it isn’t.
biorxiv.org
X-inactivation escapee domains are CTCF-cohesin independent chromatin compartments
X-chromosome inactivation involves chromosome-wide gene silencing accompanied by extensive chromatin changes, as well the loss of topologically associating domains. Yet discrete regions of the inactiv...
