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Maud Borensztein

@maudborensztein.bsky.social
540 followers 335 following 42 posts

Group Leader @igmm-montpel.bsky.social 👩‍🔬 Passionate about Development, Epigenetics and Reprogramming 🐭🧬🔬 X-chromosome inactivation aficionado! www.igmm.cnrs.fr/en/team/epigenetic…

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Reposted by Maud Borensztein
Geoff Faulkner @faulknerlab.bsky.social · 30/07/2026
Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...
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Gael Cristofari @retrogenomics.bsky.social · 30/07/2026
That’s a beautiful story that shows again how powerful long reads are for studying transposable elements. Exciting times! For accessing the Perspective piece without a paywall: www.science.org/eprint/NIKHD...
science.org
Why the X chromosome is rich in L1 mobile elements
Preferential insertion into the late-replicating inactive X explains L1 accumulation in this chromosome
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Darío Lupiáñez @dariloops.bsky.social · 21/07/2026
🚨 Job Alert - Please share 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! ✅ 4 years fully funded PhD position 💻🧪 Experimental or computational backgrounds welcome 👇 Details below #PhDPosition #PhDOpportunity #AcademicJobs
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Grand Lab @grandlab.bsky.social · 07/05/2026
Excited to share our first story led by @martinacapriati.bsky.social! How do cells control the expression of viability genes? We find that single transcription factors can drive both chromatin opening and gene activation from densely co-bound CpG island promoters, including at essential genes
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Maxim Greenberg @maxvcg.bsky.social · 06/07/2026
I had an (honestly) really fun time writing up an "In Preprints" piece on the two fantastic studies from @grandlab.bsky.social and @schubelerlab.bsky.social. Check it out here. I have also put the original threads from the authors below. journals.biologists.com/dev/article/...
journals.biologists.com
In preprints – housekeeping the housekeeping genes
The term ‘housekeeping gene’ evokes a sense of banality. These are the boring genes that hum in the background, impervious to cell state or stress. For a developmental biologist captivated by the impa...
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Deborah Bourc’his @deborahbourchis.bsky.social · 27/06/2026
Coupes drastiques du budget de la recherche + durcissement des règles d’attribution des financements ANR «Allez à l’ERC!» qu’ils disent, mais l’ERC saturée prend des mesures pour limiter les candidatures #deadend#recherchefrançaise Une petition semble vaine mais il faut commencer quelque part 👉
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Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · 13/05/2026
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇
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Oded Rechavi @odedrechavi.bsky.social · 05/05/2026
We built an AI that will tell you what will get your grant rejected. It’s a tough critique, but it’s better to know when you can still do something about it 👇 @qedscience.bsky.social
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Michael Rera @michaelrera.bsky.social · 27/04/2026
You want to design a very specific single AA mutation for CRISPR editing or interpret your newly identified natural polymorphism? This is for you 👇 with a user-friendly web tool, thanks to the PhD work of @abakamarina.bsky.social www.nature.com/articles/s41... shorturl.at/pFAZ7 shorturl.at/ogXb6
linkedin.com
Proteome-wide prediction of the functional impact of missense variants with ProteoCast
You just identified a new mutations in your favourite but don't know whether it's functional Marina Abakarova 's PhD project, with the help of Maria Ines Freiberger Arnaud Liehrmann, and under the sup...
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IGMM-Montpellier @igmm-montpel.bsky.social · 17/04/2026
🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social 📅 1 May–15 June 2026 📩 search2026@igmm.cnrs.fr 📎Full information 👇 #LifeScience #MolecularBiology #Research #PI #CNRS
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Peter Andersen @germline.bsky.social · 17/04/2026
Reminder: PhD position in my lab is open for two more weeks. How do germ cells use their own private transcription factors? Come help us find out. Fully funded. Deadline May 1. Flyer attached — please boost! 🙏
Flyer for a PhD position in the Andersen Lab on Genetic Innovation at Aarhus University, Denmark. Title: "Transcriptional regulation in Drosophila germline development." Start date between August 2026 and January 2027, application deadline May 1, 2026. The flyer describes a project on germline-specific transcription factor paralogs, funded by the Novo Nordisk Foundation (PARAGLIDE programme). Includes example data figures: genomics browser tracks, a proximity-labeling proteomics volcano plot, and fluorescence microscopy of germline tissue. Contact: pra@mbg.au.dk. Apply via phd.nat.au.dk.
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Diana Pinheiro @dianapinheiro.bsky.social · 30/03/2026
👇👇👇 If are you excited about helping us recruit and train the next generation of scientists, don't hesitate to apply! The @viennabiocenter.bsky.social is a great place to work. 🙂
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Maud Borensztein @maudborensztein.bsky.social · 30/03/2026
Yolanda and I enjoyed writing this review on X-chromosome reprogramming in the mammalian germline. 👇 Hope you'll enjoy reading it too! @biochemsoc.bsky.social #epigenetic #germline #XCI @igmm-montpel.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social
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IGMM-Montpellier @igmm-montpel.bsky.social · 09/03/2026
🦠 Quand un virus devient cheval de Troie 🔬 Cette découverte éclaire la transmission et l’évolution des deltavirus. 👉 www.insb.cnrs.fr/fr/cnrsinfo/... 👏 @karimaj.bsky.social @viroscope.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social #IGMM #CNRS #Virologie #Recherche
insb.cnrs.fr
Quand un virus en transporte un autre : le « cheval de Troie » des deltavirus
Certains virus minuscules, appelés deltavirus, ne peuvent se propager qu’en s’appuyant sur d’autres virus.
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IGMM-Montpellier @igmm-montpel.bsky.social · 23/03/2026
Save the date : Seminar by Kristina Zumer on Tuesday 24th March at 11h @uni-goettingen.de
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Jamie Hackett @jamiehackett.bsky.social · 05/01/2026
This went under the radar but answers a fundamental question in Epigenetics... From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How? Outstanding work from Mathieu Boulard and colleagues www.biorxiv.org/content/10.6...
biorxiv.org
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
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heardlab.bsky.social @heardlab.bsky.social · 15/12/2025
💡 New paper out in @natcellbio.nature.com 💥💥💥🚀🚀🚀 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation well beyond early development, in differentiated, non-dividing cells and in vivo post implantation embryos 👇👇👇👇
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IGMM-Montpellier @igmm-montpel.bsky.social · 18/11/2025
This is today !
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Maud Borensztein @maudborensztein.bsky.social · 12/11/2025
We are thrilled to host Elphège Nora next week in Montpellier 🤩 ☀️🧬 @elphegenoralab.bsky.social @cnrsbiologie.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social #transcription
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IGMM-Montpellier @igmm-montpel.bsky.social · 07/11/2025
🧬Le magazine de la Métropole de Montpellier consacre un article à Jamal Tazi, pour son rôle dans la découverte de l’Obefazimod (ABX464), molécule issue de la recherche académique et développée grâce à une collaboration public-privé exemplaire. encommun.montpellier.fr/sites/defaul...
encommun.montpellier.fr
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dandergassen.bsky.social @dandergassen.bsky.social · 11/11/2025
New paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡 Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.
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Maxim Greenberg @maxvcg.bsky.social · 28/10/2025
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
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Oded Rechavi @odedrechavi.bsky.social · 15/10/2025
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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IGMM-Montpellier @igmm-montpel.bsky.social · 13/10/2025
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍. 👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus” www.the-scientist.com/boa-constric...
the-scientist.com
Boa Constrictor Brain Cells Slither into Focus
From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.
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Naomi Moris @nmoris.bsky.social · 09/10/2025
The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍
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Development @dev-journal.bsky.social · 09/10/2025
An Interview with Azim Surani Ashley Moffett and @geraldinejowett.bsky.social spoke to Azim, recipient of both the 2025 Kyoto Prize and 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, about his non-traditional and inspirational route into academia: journals.biologists.com/dev/article/...
Picture of Azim Surani in a dark blue jumper and light blue collared shirt sitting by a microscope.
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Edda Schulz @eddaschulz.bsky.social · 06/10/2025
⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation. 👉 We discover how sex and development signals are decoded at a single gene locus. www.nature.com/articles/s41... 👇 Bluetorial
nature.com
Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology
Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.
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Kara McKinley @karalmckinley.bsky.social · 25/08/2025
Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!
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EMBO Reports @emboreports.org · 07/08/2025
DNA methylation at #retrotransposons protects the #germline by preventing NRF1-mediated #activation. -> www.embopress.org/doi/full/10....
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Mounia Lagha @laghalab.bsky.social · 28/07/2025
#jobAlert We are hiring! If you like #imaging ,gene regulation and a dynamic group please apply. We are looking for a research assistant with a master degree and prior experience in academia.
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IGMM-Montpellier @igmm-montpel.bsky.social · 28/07/2025
🚀 @hfspo.bsky.social funded Postdoc 3-year contract Start after Dec 2025 📩 Apply: mounia.lagha@igmm.cnrs.fr Subject: "[HFSP Post doc application]" 📎 CV + short research summary + cover letter 🔗 More info: euraxess.ec.europa.eu/jobs/363437 @laghalab.bsky.social @umontpellier.bsky.social @cnrs.fr
euraxess.ec.europa.eu
A PhD in biology, biophysics or a closely related field is required by the start of the appointment. Interdisciplinary profiles are strongly encouraged to apply.
- work environment:
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IGMM-Montpellier @igmm-montpel.bsky.social · 28/07/2025
🎯 Hiring: Biology Research Assistant (M/F) Join IGMM Montpellier to study gene expression dynamics during Drosophila development @laghalab.bsky.social 6-month contract, renewable up to 2 years. Start Sept 15, 2025 | Apply by Aug 11 🔗 emploi.cnrs.fr/Offres/CDD/U... #Hiring #Biology #Research #IGMM
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Assistant ingénieur en biologie (H/F)
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IGMM-Montpellier @igmm-montpel.bsky.social · 25/07/2025
🧬 Avancée majeure issue d’Abivax et de l’équipe Tazi @igmm-montpel.bsky.social @cnrs.fr @umontpellier.bsky.social @cnrsbiologie.bsky.social Le 23 juillet 2027, Abivax annonce des résultats très positifs en phase 3 pour obefazimod contre la RCH. 📈 +520 % en bourse @lemonde.fr
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BIOLuM Montpellier @biolum-montpellier.bsky.social · 25/07/2025
Fantastique !!!
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Andrau Lab @andraulab.bsky.social · 22/07/2025
Two major events today on our campus! 🚴‍♀️First, the Tour de France is passing right next to us — @cnrsoccitanieest.bsky.social! 🧬Second, our latest paper on the role of G-quadruplexes (G4s) at promoters is now online at @natgenet.nature.com!
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Michael Rera @michaelrera.bsky.social · 23/07/2025
60 days to go for applying to marie-sklodowska-curie-actions.ec.europa.eu/actions/post... if you want to join me to study ageing with an interesting new angle! #Smurfs #2PAC
marie-sklodowska-curie-actions.ec.europa.eu
Postdoctoral Fellowships
The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.
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Arnau Sebé-Pedrós @arnausebe.bsky.social · 15/07/2025
We are looking for a student to continue our work on chromatin evolution: www.nature.com/articles/s41... www.biorxiv.org/content/10.1... The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes. More info: recruitment.crg.eu/content/jobs...
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IGMM-Montpellier @igmm-montpel.bsky.social · 07/07/2025
Congratulations to the Carnesecchi lab 🍾🍾 Read below to learn more about their research 👇
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Claire Rougeulle @crougeulle.bsky.social · 18/06/2025
Join us in the #institutcurie exceptional environment to explore the mysteries of X chromosome regulation in early human development
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IGMM-Montpellier @igmm-montpel.bsky.social · 06/06/2025
Save the date : Seminar Elphège NORA - June 19h - 11am @elphegenoralab.bsky.social
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European Research Council (ERC) @erc.europa.eu · 02/06/2025
Planning to apply for #research #funding from the ERC? From the next application rounds, expect changes to the: • proposal structure • evaluation process • extra funding you can request • eligibility for Starting & Consolidator #Grants (from 2027) More 👇 europa.eu/!RPHWvv
europa.eu
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
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Maud Borensztein @maudborensztein.bsky.social · 28/05/2025
We are recruiting at @igmm-montpel.bsky.social Join us in a dynamic scientific environment in beautiful and sunny Montpellier 👩‍🔬👨‍🔬☀️ For questions, feel free to write to search2025@igmm.cnrs.fr or DM me!
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IGMM-Montpellier @igmm-montpel.bsky.social · 28/05/2025
📣 We are recruiting new group leaders in Innovative Biology! RNA biology Epigenetic regulation Cell cycle regulation Cancer, immunology Virology Application and information ⬇️ application.igmm.cnrs.fr @cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
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IGMM-Montpellier @igmm-montpel.bsky.social · 19/05/2025
📢 Mobilité NOEMI CNRS – Ingénieur·e en biologie (BAP A) 🧬 IGMM Montpellier recrute pour projets levure/cellules humaines + plateforme de purification de protéines. 📬 Plus d’infos emploi.cnrs.fr/Offres/MOBIN... @domlibri.bsky.social @oporrua.bsky.social @cnrsbiologie.bsky.social
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Ingénieur-e en expérimentation et instrumentation biologiques H/F
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IGMM-Montpellier @igmm-montpel.bsky.social · 23/05/2025
🔬 L’IGMM recrute un·e doctorant·e en biologie à Montpellier ! 🎓 Master requis, projet en biologie moléculaire et cellulaire. 📅 Candidature ici : emploi.cnrs.fr/Offres/Doctorant/UMR5535-SARADE-071 #PhD #Biologie #IGMM #Montpellier #Recrutement
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Doctorant en biologie (H/F)
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Jamie Hackett @jamiehackett.bsky.social · 15/05/2025
We are looking to take on an intern at EMBL Rome, for anyone interested in CRISPR and Epigenetics training. The traineeship is 3-12-months, in Rome (Italy), should start by July, and is supervised by the outstanding @steliostsagkris.bsky.social. #job #internship; see info below...
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Turner Lab @lab-turner.bsky.social · 14/05/2025
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
nature.com
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
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MAYosis @mayosis.bsky.social · 05/05/2025
It's going to be MAYosis !!! Register : meiosis.cornell.edu/mayosis2025/... We have it all : meiotic drive, recombination, adaptation, pairing, segregation, interference, resection, crossover landscape, chromosome axis, synaptonemal complex, chromosome dynamics ! #Meiosis4ever
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Maud Borensztein @maudborensztein.bsky.social · 06/05/2025
Happy to see that our recent work has been discussed in a News & Views @natsmb.nature.com by Christine Disteche and Xinxian Deng 😀 ⬇️ rdcu.be/ekTr1
rdcu.be
Slow awakening of the silent X chromosome in female primordial germ cells
Nature Structural & Molecular Biology - Programmed reactivation of the inactive X chromosome in mammals happens in female primordial germ cells (PGCs) to prepare for meiosis and the generation...
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IGMM-Montpellier @igmm-montpel.bsky.social · 15/04/2025
📣 New paper alert! Daniele Raimondi a ouvert son équipe de recherche récemment à l'IGMM www.igmm.cnrs.fr/en/team/ai-f... Apprenez en plus sur ses travaux ⬇️ Daniele Raimondi recently opened his team in IGMM www.igmm.cnrs.fr/en/team/ai-f... Learn more about his work ⬇️
igmm.cnrs.fr
AI for Genome Interpretation – IGMM
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