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Maier Biophysics Lab

@maierlab.bsky.social
194 followers 206 following 4 posts

Welcome to Maier Lab! Our research focuses on bacterial mechanics & evolution. Here, we update you on our current research. Account run by lab members Website: biophysics.uni-koeln.de Institute for Biological Physics, University of Cologne

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WeberLab@McGill @weber-lab.bsky.social · 21/09/2026
🚨We're hiring!!🚨 @biomcgill.bsky.social is looking for a Quantitative Cell Biologist to join our diverse and interdisciplinary community. Please share this ad broadly, and reach out if you have any questions. mcgill.wd3.myworkdayjobs.com/en-US/McGill...
mcgill.wd3.myworkdayjobs.com
Assistant Professor in Quantitative Cell Biology - Department of Biology
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
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Anthony Vecchiarelli @cellforganized.bsky.social · 19/09/2026
Applications are now being accepted for the 2027 Bacterial Cell Biology & Development GRC, June 6–11! GRS will be on June 5-6, 2027 We’ll likely be oversubscribed, so please apply early!
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John Innes Centre @johninnescentre.bsky.social · 26/06/2026
Watch the full short video on our Youtube (credit: Dr Jack Dorling) 🎥🦠:
eur03.safelinks.protection.outlook.com
Rings of power – how bacteria use circadian clocks to colonise their world - credit: Dr Jack Dorling
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Melanie Blokesch @mblokesch.bsky.social · 29/03/2026
Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications. Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101
tiny.cc
Open Positions
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Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 01/06/2026
🛠️💉It's time for engineering contractile injection systems! @chipericson.bsky.social & @davidschaumann.bsky.social introduce programmable CIS - PROCIS, combining tail length control, non-native cargo loading, and cell retargeting all in one system! www.biorxiv.org/content/10.6... 🧵 1/5
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Ákos T Kovács @evolvedbiofilm.bsky.social · 26/02/2026
Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social Application deadline on 15 March 2026 👇 careers.universiteitleiden.nl/job/Assistan...
careers.universiteitleiden.nl
Assistant/Associate/Full Professor Computational Biology
Assistant/Associate/Full Professor Computational Biology
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Waggoner Lab @labwaggoner.bsky.social · 26/02/2026
SNIPE is a widespread bacterial defence system that exploits the spatial organization of phage genome injection to specifically target viral DNA, distinguishing self from non-self in prokaryotic immune systems @nature.com @mitpress.bsky.social www.nature.com/articles/s41...
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Erin Goley @goleylab.bsky.social · 23/02/2026
Exciting line up of talks for CauloCon 2026 - includes keynotes from @brunlabcaulo.bsky.social @lamasonlab.bsky.social and @thanbichlerlab.bsky.social! Hear work from Isaac Payne and Trung Nguyen, 2 students in my lab, on Weds and Thurs. 🤩
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Jörg Vogel @jorg-vogel-lab.bsky.social · 23/02/2026
Looking for a truly unique PhD programme on RNA drugs and therapeutics? We have just opened the call for the second cohort of RNAmed-Future leaders in RNA-based medicine. More details under www.rnamed.de Please spread the word.
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George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 23/02/2026
JB Editor's Pick: Iglesias, Mongiardini et al. show that loss of the Tad pili of B. diazoefficiens results in enhanced biofilm formation - they propose a regulatory role, perhaps via cdG, for Tad impacting biofilms in this bug. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology
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EMBL Events @events.embl.org · 06/02/2026
Do you want to be part of a diverse community building a comprehensive understanding of mechanobiology across kingdoms? 🔬🧬 Then join us in Heidelberg or virtually for the #EESMechanobiology symposium: s.embl.org/ees26-06-bl Date: 9 – 12 June Abstract submission deadline: 3 March
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Marco Fumasoni @marcofumasoni.bsky.social · 02/02/2026
Now with the final graphic ✨ Beautiful artwork by Sonia Monti (scientific-visualization-solutions.com). Design by @embo.org 🧬 The Rules of the Game 📍 @gimmfoundation.bsky.social, Oeiras (PT) | June 2–5, 2026 🗓️ Register by March 1st 👉 meetings.embo.org/event/26-cel...
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 02/02/2026
iCASE PhD project available in my lab, combining microscopy method development with high throughput screening of bacteria. Applications to antibiotic drug discovery and screening for new cell division proteins. Collaboration with Cairn Research #microsky #bioimaging www.findaphd.com/phds/project...
findaphd.com
Image-based bacterial phenotyping and antimicrobial drug discovery using smart high-throughput super-resolution microscopy at University of Warwick on FindAPhD.com
PhD Project - Image-based bacterial phenotyping and antimicrobial drug discovery using smart high-throughput super-resolution microscopy at University of Warwick, listed on FindAPhD.com
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VAAM e.V. @vaam-microbes.bsky.social · 06/02/2026
✨ We've just joined Instagram! ✨Follow us there for news, updates and insights from #VAAM 📸 www.instagram.com/vaam_microbes/
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Raunser lab @raunser-lab.bsky.social · 15/01/2026
Our new movie is online, highlighting the assembly, secretion and mechanism of action of bacterial Tc toxins. We hope you enjoy it and use it for teaching purposes or just for fun. Nature is fascinating! www.youtube.com/watch?v=UfEf...
youtube.com
How bacterial Tc toxins work: secretion, pore formation and host cell disruption.
YouTube video by Max Planck Institute of Molecular Physiology
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Maier Biophysics Lab @maierlab.bsky.social · 16/01/2026
Preprint:INSIDE OUT! Experimentally and via computational modelling, we showed that chemical gradients in late-stage N.gonorrhoeae microcolonies induce spontaneous symmetry breaking. Like a jet, the inner core flows towards the periphery, leading to a global eversion and the dissemination of cells.
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Vivek Mutalik @vivekmutalik.bsky.social · 16/01/2026
This is 😮 Structural insights into the assembly and evolution of a complex bacterial flagellar motor #microsky www.nature.com/articles/s41...
nature.com
Structural insights into the assembly and evolution of a complex bacterial flagellar motor - Nature Microbiology
Structural, genetic, functional and biochemical analyses of the complex flagellar motor of Campylobacter jejuni reveal structural adaptations with an ancient origin also found more widely across bacte...
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Eduardo Rocha @epcrocha.bsky.social · 05/01/2026
The distinction between virulent & temperate phages gets fuzzier if one can find so many virulent phages in the sequences of bacterial genomes coming from standard lab "pure" cultures. Check Peter's thread on our work and the N&V by Carson & Hynes: doi.org/10.1038/s415... #phagesky #microsky
doi.org
Perfect predators persist - Nature Microbiology
If only temperate bacteriophages should be able to lie dormant in bacterial cells, why have two independent groups found thousands of virulent phages hiding in bacterial sequencing data?
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Nature Microbiology @natmicrobiol.nature.com · 05/01/2026
Nature Microbiology turns 10! 🎂 As a special treat, we take you back to the editorial team that started it all and then fast forward to take a peek into the future of microbiology through some brilliant microbiologists. #MicroSky 🦠 www.nature.com/nmicrobiol/v...
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Yves Brun lab @brunlabcaulo.bsky.social · 31/10/2025
Forgot to post the recently published version of this paper on the role of a minor pilin-like protein in surface sensing journals.asm.org/doi/10.1128/...
journals.asm.org
Stimulation of the Caulobacter crescentus surface sensing pathway by deletion of a specialized minor pilin-like gene | mBio
Surface sensing allows bacteria to colonize surfaces and form biofilms, with wide-ranging implications for bacterial survival, ecology, and human health. In Caulobacter crescentus, tight adherence (Ta...
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Emmanuele Severi @emmseveri.bsky.social · 26/09/2025
www.nature.com/articles/s41... #microsky
nature.com
Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation - Nature Communications
ParABS systems partition chromosomal DNA and low-copy plasmids in bacteria. Here, the authors elucidate the mode of interaction between ParA and ParB and clarify how ParB stimulates the ATPase activity of ParA to drive the segregation process.
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Christian Kost @kostchristian.bsky.social · 28/10/2025
#microsky #mevosky @spp2389.bsky.social A PhD position is available in my lab to work on: Emergence and self-organisation of bacterial metabolism in consortia of cross-feeding bacteria. Please RT Deadline: 12.11.25 More infos 👇 shorturl.at/rAKAT
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SPP2389 - Emergent Functions of Bacterial Multicellularity @spp2389.bsky.social · 30/10/2025
@kostchristian.bsky.social has an open PhD position as a part of #SPP2389 ! #microsky #mevosky
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Harry Low’s Lab @lowlab.bsky.social · 29/10/2025
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
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Simona Huwiler @simonahuwiler.bsky.social · 23/10/2025
Multiple small, curved, predatory bacteria (Bdellovibrio bacteriovorus) lyse the bacterial prey remnants below. How are they doing this & which predator proteins are involved in this process? See our newly released research article 📑 => rdcu.be/eL6gu 🦠 #microsky #bacteria #PredatoryBacteria
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Emmanuele Severi @emmseveri.bsky.social · 23/10/2025
www.nature.com/articles/s41... #microsky but kinda #phagesky too
nature.com
Structural characterization of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted states - Nature Communications
Marín-Arraiza and colleagues report the cryo-EM structures of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted states, providing structural insigh...
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Ariane Briegel @arianebriegel.bsky.social · 15/10/2025
Interested in bacterial sensing, signaling and regulation? Come join us in January at the GRC in sunny California! www.grc.org/sensory-tran...
grc.org
2026 Sensory Transduction in Microorganisms Conference GRC
The 2026 Gordon Research Conference on Sensory Transduction in Microorganisms will be held in Ventura, California. Apply today to reserve your spot.
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Marco Mauri @marcomauri.bsky.social · 13/10/2025
🚨 On Friday 24/10 15:30 EU, Dani Rodríguez Amor (École Normale Supérieure - Paris Sciences et Lettres) will present the talk Cooperation-driven multistability in synthetic microbial communities at the Population Dynamics Seminars. Subscription sites.google.com/view/popdyn/
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Susan Schlimpert @s-lab.bsky.social · 13/10/2025
We have a PhD opportunity available in our group @johninnescentre.bsky.social through the NRP Doctoral Training Partnership. Help us uncover the Hidden Diversity of Bacterial NLRs. Start date: October 2026. For more information and how to apply👉 biodtp.norwichresearchpark.ac.uk/projects/bey...
biodtp.norwichresearchpark.ac.uk
Beyond Immunity: Uncovering the Hidden Diversity of Bacterial NLRs (SCHLIMPERT_J26DTP) | Doctoral Training Partnership
Join us in exploring the hidden functions of ancient immune proteins in bacteria. Bacteria, like plants and animals, have evolved sophisticated systems to detect and respond to threats.
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Ákos T Kovács @evolvedbiofilm.bsky.social · 25/07/2025
The what, when, where, and why of wrinkly morphology in biofilms -in Biophysics Rev pubs.aip.org/aip/bpr/arti...
pubs.aip.org
The what, when, where, and why of wrinkly morphology in biofilms
Wrinkling is a striking emergent behavior that occurs in microbial biofilms across many species. The phenomenon originates from an intricate interplay between e
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Julia Frunzke @frunzkelab.bsky.social · 08/10/2025
Please RT: We have an opening for a junior group leader position in „Phage Biology & Biotechnology“. www.fz-juelich.de/de/karriere/... Interested candidates are encouraged to contact me via email for further details. @spp2330.bsky.social; @mibinet.bsky.social
fz-juelich.de
Junior Group Leader - Phage Biology & Biotechnology
As a leading research institution for microbial biotechnology the Institute of Bio- and Geosciences - Biotechnology (IBG-1, https://www.fz-juelich.de/de/ibg/ibg-1 ) at the Forschungszentrum Jülich foc...
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GeminiTeamLab @geminiteamlab.bsky.social · 09/09/2025
📢 A Junior Professorship (W1, tenure track) is open at the Center for Plant Molecular Biology at Uni Tübingen (@zmbp-tuebingen.bsky.social) — to work on plant protein biochemistry (composition, structure, dynamics, or regulation of protein complexes). 🌱 Great opportunity — Apply by Oct 17th!
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Şuayb Üstün @suaybuestuen.bsky.social · 22/08/2025
Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details! jobs.ruhr-uni-bochum.de/jobposting/f...
jobs.ruhr-uni-bochum.de
W1TTW2 Professorship in Membrane Biology (m/f/d)
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Rita Mateus @ritamateus.bsky.social · 01/09/2025
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
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Julie Pfeiffer @jkpfeiff.bsky.social · 18/08/2025
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Department members sit at a very long table in the hallway eating a pre-Thanksgiving potluck feast.
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Vivek Mutalik @vivekmutalik.bsky.social · 19/08/2025
#phage #phagesky
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Vivek Mutalik @vivekmutalik.bsky.social · 19/08/2025
#microsky Naturally competent bacteria and their genetic parasites – A battle for control over horizontal gene transfer? academic.oup.com/femsre/advan...
academic.oup.com
Naturally competent bacteria and their genetic parasites – A battle for control over horizontal gene transfer?
Abstract. Host-mediated natural competence for transformation of DNA and mobile genetic element (MGE)-driven conjugation and transduction are key modes of
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Eduardo Rocha @epcrocha.bsky.social · 23/07/2025
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
graphical abstract of the article the extended mobility of plasmids
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Ákos T Kovács @evolvedbiofilm.bsky.social · 14/08/2025
Cell Symposia: Host-microbiome dynamics May 10–12, 2026 | Bruges, Belgium by @cp-immunity.bsky.social @cp-cellhostmicrobe.bsky.social and @cp-trendsmicrobiol.bsky.social www.cell-symposia.com/microbiome-2...
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Fabrice Jean-Pierre @fabricejpierre.bsky.social · 14/08/2025
Cool! #microsky
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Kranzusch Lab @kranzuschlab.bsky.social · 14/08/2025
www.nature.com/articles/s41...
nature.com
Characterization of an amyloid-based antiphage defence system in Escherichia coli - Nature Microbiology
Prion-like proteins in Escherichia coli trigger an abortive infection mechanism in response to phage infection—a process similar to amyloid-mediated immune signalling in fungi and animals.
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Amanda Amodeo @aaamodeo.bsky.social · 14/08/2025
My Department (Biology) at @dartmouthartsci.bsky.social is hiring this year! We have an opening for a Tenure Track Cell and/or Molecular biologist (broadly defined). Please share with your trainees/labmates/friends and reach out if you have questions. apply.interfolio.com/171625
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Biozentrum, University of Basel @biozentrum.unibas.ch · 02/06/2025
PhD student – Physics of bacterial infections www.biozentrum.unibas.ch/open-positio... @biozentrum @unibas.ch #Biozentrum #Basel #research #science #joboffer #hiring #job #recruiting #careers #phd #physics #bacterial #infection
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Courtney Ellison @ckellison.bsky.social · 22/05/2025
Excited to share the newest preprint from the lab for my first post! Driven by @tayellisonwrites.bsky.social and @ianyyen.bsky.social with Lynne Howell we show the protein FimX has diverged in function away from regulating pilus extension to instead regulate pilus localization in A. baylyi
biorxiv.org
FimX regulates type IV pilus localization via the Pil-Chp chemosensory system in Acinetobacter baylyi
Type IV pili (T4P) are widespread dynamic appendages required for diverse prokaryotic behaviors including twitching motility, biofilm formation, and DNA uptake leading to natural transformation. Altho...
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Mark O. Martin @markowenmartin.bsky.social · 29/05/2025
Thursday! So #MattersMicrobial Episode 93: Dr. Despoina Mavridou did a live podcast with me at UT-Austin. Hijinks and discussion of AMR and how protein folding can help against this growing threat. @microbe.tv @ASMicrobiology @univpugetsound youtu.be/nSO2Tv6j1J0?...
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 29/05/2025
Update: David Roberts, postdoc in my lab, tested the GraceBio GeneFrame substitute. A few quirks but extremely promising. Good: B. subtilis cells grew quite happily in overnight time lapse. Growth rate comparison to GeneFrames not done yet but in the works.
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 29/05/2025
Update on initial results of testing GraceBiolabs potential replacement to Thermo Fisher GeneFrames, widely used for bacterial cell biology microscopy time lapses but soon to be discontinued #microsky #bioimaging
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Universität Tübingen @unituebingen.bsky.social · 22/05/2025
Die Universität Tübingen erhält sechs #Exzellenzcluster, die im Rahmen der #Exzellenzstrategie vom 01.01.2026 an sieben Jahre lang gefördert werden! Darunter drei Cluster, die bereits etabliert sind und eine erneute Förderung erhalten. uni-tuebingen.de/universitaet... #ExStra #Forschung #UniTübingen
Das Bild zeigt einen Brunnen vor der Neuen Aula. Darunter der Text: Sechs Exzellenzcluster werden in Tübingen gefördert.
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Simona Huwiler @simonahuwiler.bsky.social · 19/05/2025
🛠️Toolbox 🛠️ out to modulate gene expression & protein secretion in a predatory bacterium. 📑Preprint from my group below. Many thanks to L. Mihajlovic @ljmihajlovic.bsky.social, L. Hofacker, F. Lindner, P. Jayakumar & A. Diepold @diepold-lab.bsky.social! #MicroSky #SyntheticBiology #PredatoryBacteria
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Asaf Levy @asaflevylab.bsky.social · 14/05/2025
A new preprint from the lab in collaboration with Feng Jiang. www.biorxiv.org/content/10.1... This is a thread for you if you're interested in secretion systems, phages, and evolution. The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
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