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Marco Fumasoni

@marcofumasoni.bsky.social
1.2K followers 1.5K following 42 posts

Biologist | Group leader of the Genome Maintenance and Evolution lab @gimminstitute.bsky.social | Previously @IGC, @harvardmcb.bsky.social and @ifomresearch.bsky.social | fumalab.github.io

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Reposted by Marco Fumasoni
Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Harmit Singh Malik @harmitmalik.bsky.social · 24/06/2026
I know it seems like a heretical idea, but one way to figure out if a preprint is really interesting (to you) is... to read the preprint. Then, in the spirit of sharing, send a note to authors: a simple kudos or a more detailed question. I do this a dozen times a year. It's awesome. Try it.
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EMBL Events @events.embl.org · 23/06/2026
🚨 Abstract submission deadline is approaching for #EMBOEvoEco! If you want to be part of the EMBO Workshop focusing on uncovering the mechanistic foundations of ecological and evolutionary processes. Submit your abstract by 30 June: s.embl.org/eae26-01-bl
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Proceedings of the National Academy of Sciences @pnas.org · 18/06/2026
Researchers selected yeast cells for small size for 1,500 generations, achieving a fourfold modal volume reduction, and identified mutations in nutrient-sensing and cell-cycle pathways that enabled shrinkage while maintaining relatively high fitness. In PNAS: ow.ly/zezn50ZcU0y
Light micrographs of wild type and evolved small-cell populations at different cell-cycle stages.
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Marco Fumasoni @marcofumasoni.bsky.social · 19/06/2026
Our paper on the evolution of cellular miniaturization is now out in PNAS! www.pnas.org/doi/10.1073/... A short recap 🧵
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Marco Fumasoni @marcofumasoni.bsky.social · 12/06/2026
A few snapshots from the @embo.org workshop “The Rules of the Game: biophysical and molecular principles in cellular evolution” — and an excuse to thank everyone who made it such a fun, stimulating, and inspiring few days at @gimminstitute.bsky.social #EMBORulesOfTheGame
Group Photo
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Human Frontier Science Program @hfspo.bsky.social · 11/06/2026
How do we fund and publish research that doesn't fit neatly into a single discipline? Last week, at the #EMBORulesOfTheGame, #HFSP Chief Scientific Officer Guntram Bauer presented how HFSP supports #frontierscience across disciplines and borders. @embo.org
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Statistical Physics of Cells and Genomes @spcggroup.bsky.social · 11/05/2026
New SPCG preprint in collaboration with the Amir lab We solve an accumulator model of cell division with noisy threshold and memory, finding a continuum of strategies from timer to adder to sizer and that extrinsic noise is essential to explain E. coli size fluctuations. arxiv.org/abs/2605.070...
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Marco Fumasoni @marcofumasoni.bsky.social · 08/05/2026
The final program for the EMBO Workshop “The rules of the game: biophysical & molecular principles in cellular evolution” is online! A few seats are still available if you want to attend (Deadline May 15th) @embo.org @gimminstitute.bsky.social meetings.embo.org/event/26-cel...
meetings.embo.org
The rules of the game: biophysical & molecular principles in cellular evolution
Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…
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Marco Fumasoni @marcofumasoni.bsky.social · 07/05/2026
What a nice summary of our preprint on cellular miniaturization! Thank you @anastasiamoraiti.bsky.social for writing this wonderful @prelights.bsky.social!
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Marco Fumasoni @marcofumasoni.bsky.social · 27/03/2026
FumaLab milestone unlocked this week: first PhD graduate 🎓 Congrats Dr. (and resident sous chef!) @mariananatalin6.bsky.social!!! — proud and lucky PI.
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Marco Fumasoni @marcofumasoni.bsky.social · 04/03/2026
Some of us know how sweet procrastination can be! If you feel the same, good news: The abstract deadline for the EMBO Workshop has been extended to March 19! Don’t miss the opportunity to present your work June 2–5 2026 in Oeiras, Portugal!
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Thibaut Brunet @thibautbrunet.bsky.social · 28/02/2026
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)
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EMBO @embo.org · 26/02/2026
EMBO was part of the group that developed DORA's new introductory course on #ResponsibleResearchAssessment. 🧪 We’re pleased to see its launch, more info here: sfdora.org/2026/02/23/new-introduct…
sfdora.org
Fostering Responsible Research Assessment: DORA Launches New Introductory Course | DORA
DORA is delighted to announce the launch of its Introduction to Responsible Research Assessment (RRA) Course. This online, self-paced course provides an approachable, entry-level curriculum for anyone at any career stage and in a variety of roles to learn about RRA. While the course is free for individuals to take, it requires registration, and provides the option of issuing a certificate for each of its four lessons and one for its full completion.
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GIMM Institute @gimminstitute.bsky.social · 06/02/2026
GIMM Fest returns September 17–19 with three days dedicated to the future of science and health, this year focusing on microbes. 🦠 Join researchers and innovators for a programme designed to promote scientific exchange and collaboration.
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Raquel A Oliveira @raoliveira.bsky.social · 17/02/2026
🧵 Thread: What happens when transcription isn’t properly shut off during mitosis? Our new preprint explores just that 👇 www.biorxiv.org/content/10.6...
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Marco Fumasoni @marcofumasoni.bsky.social · 02/02/2026
Now with the final graphic ✨ Beautiful artwork by Sonia Monti (scientific-visualization-solutions.com). Design by @embo.org 🧬 The Rules of the Game 📍 @gimmfoundation.bsky.social, Oeiras (PT) | June 2–5, 2026 🗓️ Register by March 1st 👉 meetings.embo.org/event/26-cel...
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EMBO @embo.org · 19/12/2025
Join the dialogue on the #evolution of cellular processes at the EMBO Workshop "The rules of the game: Biophysical & molecular principles in cellular evolution" in #Oeiras, PT, 2–5 June 2026. Deadline: 1 March meetings.embo.org/event/26-cellular… #EMBORulesOfTheGame #EMBOevents 🧪
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Marco Fumasoni @marcofumasoni.bsky.social · 18/12/2025
📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️ “The rules of the game: biophysical & molecular principles in cellular evolution” Apply by March 1st! Please repost to help spread the word! meetings.embo.org/event/26-cel... #EMBORulesOfTheGame @gimmfoundation.bsky.social
meetings.embo.org
The rules of the game: biophysical & molecular principles in cellular evolution
Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…
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Marco Fumasoni @marcofumasoni.bsky.social · 09/12/2025
🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥 www.biorxiv.org/content/10.6...
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Gautam Dey @gautamdey.bsky.social · 27/11/2025
So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍 The mighty yeast reveals what we believe are general principles of centromere evolution! Behind the curtain: communities.springernature.com/posts/counti... #MEvoSky 🧪🌎
communities.springernature.com
Counting Chromosomes: The Simple Idea That Unlocked the Rules Behind Centromere Evolution
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Jana Helsen @helsenjana.bsky.social · 26/11/2025
How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉 doi.org/10.1038/s41586-025-09779-1
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Marco Fumasoni @marcofumasoni.bsky.social · 27/10/2025
Now published on @plos.org Computational Biology! Same findings as the preprint, with improved analyses suggested by reviewers! Check it out and let us know how RepliFlow works for you! journals.plos.org/ploscompbiol...
journals.plos.org
Model-based inference of cell cycle dynamics captures alterations of the DNA replication programme
Author summary The cell cycle is the coordinated sequence of events between two consecutive cell divisions. In eukaryotes, the cell cycle consists of four main phases: G1, S, G2, and mitosis. Understa...
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Anshul Kundaje @anshulkundaje.bsky.social · 16/09/2025
I'm curious if other mid career PIs have considered completely abandoning the trad publication model. We've been making gradual moves towards that end goal. But it's been difficult to completely jump ship for one main reason for me at least. 1/
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Alexandra Dallaire @alexdallaire.bsky.social · 03/09/2025
I’m super happy to present the first discoveries of the RIKEN-Cambridge Joint Crop Symbiosis Research Team, based in Japan 🇯🇵 doi.org/10.1101/2025... A thread 👇
doi.org
Reductive evolution of the DNA replication machinery in endosymbiotic fungi
The molecular machinery for replicating and repairing DNA accurately is critically important for life and highly conserved across the Tree of Life. Here we show that two major lineages of fungi, Glome...
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liti_nice @litinice.bsky.social · 03/07/2025
how (yeast) cells re-climb the fitness landscape when they are reprogrammed to a different telomere DNA sequences (human-like)? read the latest from @melaniadangiolo.bsky.social etal , with great help and insights from Eric Gilson, Jonas Warringer and @juliamuenzner.bsky.social (& Ralser lab)
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Molecular Systems Biology @molsystbiol.org · 03/07/2025
@mariananatalin6.bsky.social @marcofumasoni.bsky.social show evolutionary repair in response to DNA replication stress in yeast is predictable and consistent across different environments #CompensatoryEvolution #NutrientAvailability #ReplicationStress #GxE ➡️ www.embopress.org/doi/full/10....
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Gilles FISCHER @gillesfischer.bsky.social · 09/06/2025
📢 New paper out in Mol Syst Biol! During the development of WT yeast colonies, small cell subpopulations experience transient, high-intensity mutational bursts. Such hypermutation episodes are modulated by the DNA damage tolerance pathway 🧬 🔗 www.embopress.org/doi/full/10....
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Melania D'Angiolo @melaniadangiolo.bsky.social · 03/07/2025
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response. www.biorxiv.org/content/10.1...
biorxiv.org
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
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Centre de Regulació Genòmica (CRG) @crg.eu · 01/07/2025
Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute. www.crg.eu/en/news/moni...
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Monica Bettencourt-Dias @monicabettencourt.bsky.social · 01/07/2025
Happy to be the next (and 1st female) @crg.eu director. The CRG always stood out to me, for its excellence in understanding life's principles, with implications for health and biodiversity, & its collaborative, open and innovative way of doing science. Thrilled to join its amazing community in 2026!
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Marco Fumasoni @marcofumasoni.bsky.social · 26/06/2025
The work of brilliant PhD student @mariananatalin6.bsky.social is now out in @molsystbiol.org! We asked how nutrients shape compensatory evolution to DNA replication stress. We find changes in physiology and adaptation rates, yet core genetic adaptation remains robust! See her thread for details!👇
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Kenichi Tsuda @kenichitsuda.bsky.social · 16/05/2025
This is wild. Chromosome distributions into different nuclei! Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi www.science.org/doi/10.1126/...
science.org
Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...
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IRB Barcelona @irbbarcelona.org · 13/05/2025
🔬 Just like species evolve to survive, tumours adapt to resist treatment. A new computational tool reveals how cancers rewire driver genes to beat chemotherapy. Published in @natcomms.nature.com Read the news ➡️ bit.ly/43tyKko #CancerResearch #Genomics #ComputationalBiology #DrugResistance ⬇️
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Marco Trizzino @marcotrizzino.bsky.social · 07/05/2025
And just like that, overnight our lab loses two 5-year R01s (both of which just started) because of the new NIH rules about foreign co-PIs. This is so painful.
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Marco Fumasoni @marcofumasoni.bsky.social · 28/04/2025
🗞️New preprint out! Together with Adolfo Alsina and Pablo Sartori (both not on here), we combined experiments and theory to extract detailed information on DNA replication dynamics from simple DNA content flow cytometry data. www.biorxiv.org/content/10.1...
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jobRxiv @jobrxiv.org · 19/10/2023
Postdoctoral fellow position in the Genome Maintenance and Evolution lab @ jobrxiv.org/job/inst... #ScienceJobs #AcademicSky
jobrxiv.org
Postdoctoral fellow position in the Genome Maintenance and Evolution lab @
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
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Marco Fumasoni @marcofumasoni.bsky.social · 10/10/2023
🎺Please RT! We have a funded #Postdocposition in our lab at @IGCiencia in Portugal 🇵🇹🇪🇺! Come and join us in exploring the wonders and evolution of genome maintenance processes, and engage with the extended #LifeScience community in #Lisbon! Details here: fumalab.github.io/join
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Mark A. Hanson @hansonmark.bsky.social · 29/09/2023
The strain on scientific publishing 📄: We've got issues. Scientists overwhelmed, editors overworked, constant special issue invites, mass article retractions, journal delistings… JUST WHAT IS GOING ON!? See: arxiv.org/abs/2309.15884 A 🧵1/n #AcademicChatter #PublishOrPerish #PhDAdvice #PhDChat
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