Reposted by Jason Rehg
Excited to see this preprint from @drjennkim.bsky.social @kr-maynard.bsky.social, Annie Ciernia and colleagues. I've highlighted this approach and toolset in several recent talks: spatial transcriptomics isn't just about the gene expression -
www.biorxiv.org/content/10.6...
biorxiv.org
Spatially-resolved integration of microglia morphological diversity and gene expression using Visium with protein co-detection
Microglia exhibit a dynamic range of morphologies that actively shift in response to local environmental cues. There has been a concerted effort as a field to move away from dualistic characterization...