iiinova — where your digital self keeps evolving

Louise Huuki-Myers @lahuuki.bsky.social · 11/12/2025

Excited to share our latest preprint from @lieberinstitute.bsky.social spatial + single-cell RNA-seq map the ERC & explore how AD risk shapes gene expression doi.org/10.1101/2025... Our major finding: “APOE E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex”

Experimental design for LIBD LFF Spatial ERC project

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Louise Huuki-Myers @lahuuki.bsky.social · 28/05/2025

Learning more about APOE differences in the cell types of the brain 🧠 I presented "APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease" from @zhaonaa.bsky.social at our team journal club, check it out! doi.org/10.1016/j.ne... ▶️ youtu.be/L4J9jFS-Pic

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Redirecting

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Reposted by Louise Huuki-Myers

Manisha Barse @mbarse.bsky.social · 22/05/2025

Hi! Check my journal club talk: smart ML method to deconvolute pooled snRNA-seq using sex-specific expression🧬 Thanks @daylab.bsky.social & @rphillips3.bsky.social for this approach🙌 🎥 youtu.be/zpeCFwYfV3o 🛝 speakerdeck.com/manishabarse #snRNAseq #ML #Bioinformatics @lieberinstitute.bsky.social

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[2025-04-23] Journal club on "[...] deconvolution of pooled snRNA-seq using sex-dependent gene expr"

YouTube video by Leonardo Collado Torres

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Louise Huuki-Myers @lahuuki.bsky.social · 14/02/2025

Check out my journal club presentation on the crumblr pre-print from Hoffman and Roussos, a new method to analyze differential composition in #singlecell data 🍪 Looks very useful for single cell RNA-seq data with case/control study design 🤔 📄 doi.org/10.1101/2025... ▶️ www.youtube.com/watch?v=Hi5E...

doi.org

Fast, flexible analysis of differences in cellular composition with crumblr

Changes in cell type composition play an important role in human health and disease. Recent advances in single-cell technology have enabled the measurement of cell type composition at increasing cell ...

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Reposted by Louise Huuki-Myers

🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 12/02/2025

Check our recent video "[2025-01-29] R/Bioconductor-powered Team Data Science: TLDR version 2025" youtu.be/alL-g2roXxM We go over what analyses our @lieberinstitute.bsky.social has expertise on 💻 Slides orchestrated by @lahuuki.bsky.social at speakerdeck.com/lahuuki/2025... 👥 go.bsky.app/53gy4UP

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Louise Huuki-Myers @lahuuki.bsky.social · 04/12/2024

Reading the instructions first next time 😅 completed "Ceres Search" - Day 4 - Advent of Code 2024 #AdventOfCode adventofcode.com/2024/day/4

adventofcode.com

Day 4 - Advent of Code 2024

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Louise Huuki-Myers @lahuuki.bsky.social · 02/12/2024

I've completed "Red-Nosed Reports" - Day 2 - Advent of Code 2024 🔴 #AdventOfCode adventofcode.com/2024/day/2

adventofcode.com

Day 2 - Advent of Code 2024

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Reposted by Louise Huuki-Myers

🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 12/11/2024

I decided to make a starter pack for members/alumni of @lieberinstitute.bsky.social "Data Science Team 1" 💻 Initially led by @aejaffe.bsky.social until 2020/09; then by me. In 2024, the team became part of the Division of Translational Neuroscience led by @martinowk.bsky.social go.bsky.app/53gy4UP

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Louise Huuki-Myers @lahuuki.bsky.social · 12/11/2024

Hi Bluesky! 👋 I'm Louise Huuki-Myers I work on transciptomic research in the brain 🧠🧬 @lieberinstitute.bsky.social and am Studying for my PhD in #neuroscience at the University of Cambridge. Excited to share more about neurosci research and #Rstats here 🦋

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