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PacBio

@pacbio.bsky.social
5.8K followers 12K following 830 posts

Our mission is to enable the promise of genomics to better human health by creating the world’s most advanced sequencing technologies.

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PacBio @pacbio.bsky.social · 28/09/2026
Hammond et al. found HiFi WGS F1 scores for SNVs & indels exceeded 99% at ~15x & ~25x coverage. 📊 Strong data can strengthen the scientific case for your grant. Learn how to select the right evidence + access PacBio grant resources & free 1:1 support: bit.ly/4hk5LGI
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PacBio @pacbio.bsky.social · 25/09/2026
Microbial studies need more than answers. They need scale. 🧬 One Vega SPRQ-Nx run can support up to 384 microbial de novo assembly samples, 96 shotgun metagenomic profiling communities, or 1,536 Kinnex 16S rRNA communities. 📖 Download the playbook: bit.ly/4zJLPV4
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PacBio @pacbio.bsky.social · 23/09/2026
Benchmarking by Harvey et al. shows PacBio HiFi achieves higher indel & SV recall at 20x than ONT achieves at 60x+. 📊 Citing the right peer-reviewed data is key to a winning grant proposal. See how our literature library helps you write yours faster: bit.ly/4ycWZ3q
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PacBio @pacbio.bsky.social · 22/09/2026
September is NICU Awareness Month. 💙 When every hour matters in time-critical cases, rapid PacBio HiFi whole-genome sequencing delivers a complete view of the genome to help researchers investigate complex genetic changes. 📖 Access the resource bundle: bit.ly/4eYvYIp
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PacBio @pacbio.bsky.social · 22/09/2026
We’re excited to announce 4 winners for the 2026 Metagenomics SMRT Grant! 🧬 From infant resistomes and hereditary cancer to soil pathogens and HPV persistence, see how these researchers are driving discovery with PacBio HiFi sequencing. Meet the awardees: bit.ly/4rotusF
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PacBio @pacbio.bsky.social · 18/09/2026
Could long-read sequencing improve your targeted workflow? Explore how PacBio HiFi sequencing supports repeat expansion, HLA typing, and PGx, while Vega SPRQ-Nx chemistry delivers lower DNA input and faster runs. 📖 Read the playbook: bit.ly/4wTy43t
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PacBio @pacbio.bsky.social · 17/09/2026
Writing a grant? Let us help build your case for funding. 🧬 Answer a few quick questions about your project and grant stage to get tailored feasibility data, budget guidance, and evidence for HiFi sequencing. Get started: bit.ly/4h1ny3W
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PacBio @pacbio.bsky.social · 17/09/2026
This #InternationalMicroorganismDay, we celebrate the tiny organisms with an enormous impact on health, ecosystems, food, and science. PacBio highly accurate long-read sequencing helps researchers reveal microbial diversity in greater detail. Tech note: bit.ly/4yGM5Cz
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PacBio @pacbio.bsky.social · 17/09/2026
Which platform delivers the most reliable environmental metabarcoding data? A new study compares Illumina, ONT, and PacBio HiFi sequencing across real soil samples, demonstrating why HiFi comes out on top for accuracy and taxa recovery. Read the full breakdown here: bit.ly/4is1RfX
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HiFi sequencing sets the benchmark for environmental health metabarcoding - PacBio
A new benchmarking study comparing PacBio, Illumina, and Oxford Nanopore finds that HiFi sequencing delivers the lowest error rate and highest taxa recovery for environmental metabarcoding. Here's wha...
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PacBio @pacbio.bsky.social · 16/09/2026
Catch our expert session on new SPRQ-Nx chemistry for the Vega system! 🧬 See what changes for your workflow: • Up to 90 Gb/run • 500 ng input for limited samples • Faster turnaround times • 21 CFR Part 11 support for GMP labs Access the Q&A: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 15/09/2026
At the Nordic Conference on Future Health (NCFH) today? Join our workshop at 15:30 to explore what’s next in HiFi sequencing! Discover updates on Revio and Vega, and see how HiFi is advancing population genetics. 🧬 Connect with the PacBio team on-site: bit.ly/3Sq8KUt
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PacBio @pacbio.bsky.social · 14/09/2026
⏰ Last chance to register! Join our expert panel discussion to learn why long-read sequencing has become an essential foundation for modern multiomics & how it accelerates precision medicine. Save your spot: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing #Webinar
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PacBio @pacbio.bsky.social · 11/09/2026
Telomere-to-telomere genome assemblies are expanding across the tree of life! 🧬 A new Cell Genomics collection features T2T genomes from humans to songbirds, equids, and primates, revealing dark regions of the genome powered by HiFi sequencing. Read the full blog here: bit.ly/4xoxgnY
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Complete telomere-to-telomere genome assembly across the tree of life - PacBio
A new collection of studies shows how HiFi sequencing is making telomere-to-telomere genome assembly faster, broader, and more accessible — from single-library workflows that produce near-T2T diploid ...
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PacBio @pacbio.bsky.social · 10/09/2026
Explore our Vega expert session to see how SPRQ-Nx chemistry delivers 50% more HiFi data (up to 90 Gb/run), ~40% lower cost per Gb, & 500 ng DNA input for limited samples. 🚀 See how 21 CFR Part 11 support enables regulated workflows. Get access here: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 09/09/2026
Heading to #NCFH2026? 🧬 Join our workshop to explore what’s next in HiFi sequencing with Revio, featuring Prof. Lili Milani & Riki Aydeniz. Learn about population-scale genomics & SPRQ-Nx. Meet us on-site: bit.ly/3Sq8KUt #PacBio
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PacBio @pacbio.bsky.social · 08/09/2026
PacBio CEO Mark Van Oene explains why accurate, high-quality long-read data is foundationally important for AI-driven therapeutic research. Watch the clip, then hear the full conversation on @mendelspod: bit.ly/468AYq3
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PacBio @pacbio.bsky.social · 08/09/2026
Heading to NCFH 2026 next week? Join our corporate workshop to discover what’s next in HiFi sequencing with Revio and Vega, explore product updates, and see how HiFi powers population genetics! 🧬 Book a meeting to connect with the PacBio team at NCFH: bit.ly/3Sq8KUt
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PacBio @pacbio.bsky.social · 07/09/2026
Fewer samples. More data. Faster answers. 🧬 That's what's new with Vega SPRQ-Nx chemistry. Our HiFi Playbook for Biopharma explores how lower DNA input, shorter run times, & 21 CFR Part 11 support help streamline therapeutic research. 📖 Download here: bit.ly/3UiQDjV
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PacBio @pacbio.bsky.social · 04/09/2026
SPRQ-Nx chemistry for the Vega system is here! 🧬 Supercharge your benchtop HiFi sequencing with up to 90 Gb of data per run, lower DNA input requirements, full methylation calling, & 21 CFR Part 11 support. Read the blog to see what’s new: bit.ly/3Uizffa
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PacBio @pacbio.bsky.social · 03/09/2026
PacBio CEO Mark Van Oene joined @mendelspod this week to talk newborn screening, genomic information from birth, and where long-read sequencing could take us next. Catch the full episode here: bit.ly/4yoMkSZ
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PacBio @pacbio.bsky.social · 03/09/2026
Bring high-quality long-read microbial genomics closer to the bench! 🧬 With Vega & SPRQ-Nx chemistry, access HiFi sequencing for isolate assembly, metagenomic profiling, & full-length 16S studies. 📖 Download the HiFi Playbook for Microbiology: bit.ly/4zJLPV4
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PacBio @pacbio.bsky.social · 02/09/2026
Step into a new era of long-read multiomics! 🧬 Join leading experts as they share how long-read sequencing advances rare disease diagnostics, uncovers neurodegenerative mechanisms, & supports AI-driven therapeutic discovery. Register: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing
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PacBio @pacbio.bsky.social · 01/09/2026
Watch our expert session on Vega benchtop long-read sequencing with SPRQ-Nx chemistry! 🧬 • 50% more HiFi data (up to 90 Gb/run) • ~40% lower cost per Gb • 500 ng DNA input Access the full presentation and Q&A: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 31/08/2026
Find your ideal sequencing match: bit.ly/3QUZRl5 🧬 Answer 3 quick questions in under a minute to get matched with a personalized HiFi Fit Kit tailored to your specific research goals. Get instant access to your customized resource bundle!
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PacBio @pacbio.bsky.social · 27/08/2026
Difficult genomic regions? Limited DNA samples? 🧬 The HiFi Playbook for Clinical Targeted Sequencing explores how Vega SPRQ-Nx chemistry delivers highly accurate long-read data with lower DNA input & shorter run times. 📖 Download the playbook: bit.ly/4wTy43t #TargetedSequencing
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Reposted by PacBio
Matt Holt @holtjma.bsky.social · 27/08/2026
Our article introducing Aardvark for variant benchmarking is now published in Genome Biology! “Aardvark: sifting through differences in a mound of variants” DOI: doi.org/10.1186/s130... GitHub: github.com/PacificBiosc... Follow along for some highlights… 1/N
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Client Challenge
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PacBio @pacbio.bsky.social · 26/08/2026
Accelerate time-critical genomic research with rapid HiFi WGS! 🧬 Our end-to-end workflow delivers genome-wide variant calls in under 30 hours, capturing structural variants, repeat expansions, & phased haplotypes. Access your complimentary resource bundle: bit.ly/4eYvYIp
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PacBio @pacbio.bsky.social · 25/08/2026
Join our webinar to explore how long-read multiomics is redefining human disease research! 🧬 Learn how leading scientists integrate genomic, epigenomic, & proteomic data to advance rare disease, neurodegeneration, & AI drug discovery. Register: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing
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PacBio @pacbio.bsky.social · 24/08/2026
From targeted amplicons in 2013 to 2,000+ human genomes today! 🧬 See how Dr. Adam Ameur, Uppsala University, & SciLifeLab are scaling the Genome of Sweden project using PacBio Revio & SPRQ-Nx chemistry to lower population genomics costs. Read the story: bit.ly/4gO6Fea #PacBio #Revio #SPRQNx
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PacBio @pacbio.bsky.social · 21/08/2026
Featured in The Scientist: Dr. Alexander Hoischen discusses how long-read sequencing on the Revio system is helping end the rare disease diagnostic odyssey by filling the gaps left by short reads. Read the interview: bit.ly/4i3LKFl #PacBio #Revio #RareDisease #HiFiSequencing
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PacBio @pacbio.bsky.social · 20/08/2026
Last call! Don't forget to register for our upcoming expert panel on PacBio HiFi sequencing in biopharma and biotech R&D. Learn how industry leaders apply long-read sequencing to drug discovery, gene editing, and mRNA therapeutics. Register now: bit.ly/4g3QSX4 #PacBio #Biopharma #DrugDiscovery
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PacBio @pacbio.bsky.social · 19/08/2026
Ready to optimize your next sequencing project? Skip the manual searching and let our quick quiz find your tailored setup in under a minute. Answer 3 fast questions to unlock your custom HiFi resource kit: bit.ly/3QUZRl5 #PacBio #HiFiSequencing #Genomics
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PacBio @pacbio.bsky.social · 18/08/2026
Leveling the playing field, one long read at a time. Vega SPRQ-Nx chemistry is now shipping! Bring higher throughput, lower DNA input, shorter run times, and expanded methylation detection to your benchtop. What will you discover? Learn more: bit.ly/3TCbMoR
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PacBio @pacbio.bsky.social · 17/08/2026
AI is reshaping drug discovery, but models are only as good as the data they learn from. Read our new blog on how high-accuracy HiFi sequencing provides the rich multiomic foundation AI needs to drive biopharma breakthroughs. Explore the blog: bit.ly/4gg3L0y #PacBio #Biopharma #AI #DrugDiscovery
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How long-read sequencing builds the foundation for AI-driven biopharma - PacBio
Explore how long-read sequencing provides high-quality multiomic data to support AI-driven discovery in biopharma.
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PacBio @pacbio.bsky.social · 14/08/2026
When should you choose hybrid capture for targeted HiFi sequencing? It is ideal for larger panels, custom target designs, and transitioning short-read workflows. Learn how HiFi sequencing enables comprehensive variant detection and phasing: bit.ly/45WSOMq
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PacBio @pacbio.bsky.social · 13/08/2026
What could your research accomplish with more data from less sample? The new Vega SPRQ-Nx chemistry brings higher output, lower DNA input, and shorter run times to biopharma workflows. Download the HiFi Playbook for Biopharma to learn more: bit.ly/3TCbMoR
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PacBio @pacbio.bsky.social · 12/08/2026
T2T genomics is quickly becoming less of an endpoint and more of a starting point for discovery. A new Cell issue features 13 papers on complete diploid genome assemblies across species like humans, marmosets, horses, giraffes, and more. Explore the research: bit.ly/4wAdZiw
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PacBio @pacbio.bsky.social · 11/08/2026
Take the guesswork out of choosing your next sequencing strategy! 🧬 Answer 3 quick questions about your research goals to get matched with a personalized HiFi Fit Kit in ~45 seconds. Take the quiz for instant access to your customized guide: bit.ly/3QUZRl5
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PacBio @pacbio.bsky.social · 11/08/2026
Register for our webinar on long-read sequencing for biopharma and biotech R&D! Hear an expert panel discuss how PacBio HiFi sequencing drives high-confidence decisions across drug discovery, gene editing, and mRNA development. Save your spot: bit.ly/4g3QSX4
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PacBio @pacbio.bsky.social · 10/08/2026
How does Illumina TruPath compare with PacBio HiFi WGS? Using publicly available HG002 benchmark data, this post compares several examples of read support, variant calling, phasing, methylation, and the use of pangenome references for each approach. Explore the blog: bit.ly/4wfwGYB
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Measuring – not guessing – the true path - PacBio
See how PacBio HiFi WGS compares with Illumina TruPath Genome using HG002 benchmark data, including variant calling accuracy, read support, and methylation analysis.
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PacBio @pacbio.bsky.social · 07/08/2026
What can you learn from a clinical lab's PureTarget implementation? Discover how the team at CHU Nîmes in France implemented #PacBio PureTarget and transitioned to routine clinical use in just ~3 months to expand repeat expansion testing. Read the story: bit.ly/4fMGHWI
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PacBio @pacbio.bsky.social · 06/08/2026
Last call! Register for our New Technology Session: HiFi Long-Read #Bioinformatics Bootcamp. Learn to turn raw data into insights, master file formats and workflows for genomes or transcriptomes, and get on-demand lessons plus live Q&A access. Save your spot: bit.ly/4yADNx5
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PacBio @pacbio.bsky.social · 05/08/2026
Supercharge your sequencing lab with Vega and SPRQ-Nx chemistry! ✨ Experience higher yield, lower DNA input, and fast run times. Whether you work in biopharma, clinical targeted, or microbial genomics, explore our 3 HiFi Playbooks and download yours: bit.ly/3TCbMoR
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PacBio @pacbio.bsky.social · 05/08/2026
Big updates coming to Vega! SPRQ-Nx chemistry drops cost per Gb by 40% with 90 Gb yield, $995 run pricing, 500 ng input minimums, 2-to-4 hour run times, and 21 CFR Part 11 compliance controls. Read the full press release to explore the full specs: bit.ly/3Rxyjmd
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PacBio @pacbio.bsky.social · 04/08/2026
De novo variant discovery in 44% of unresolved cases, T2T pangenomes, and single-molecule epigenomics. See how HiFi sequencing is redefining precision medicine from the keynotes at APAC PRISM 2026 in Fukuoka. Read the recap and watch on demand: bit.ly/44Ye7Nm #PacBioPRISM #Fukuoka #PacBio #APAC
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APAC PRISM 2026 highlights: Advancing research with HiFi sequencing - PacBio
Highlights - The 2026 APAC PRISM event in Fukuoka, Japan, featured scientific sessions covering the latest developments in HiFi sequencing.
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PacBio @pacbio.bsky.social · 04/08/2026
Find your HiFi Fit Kit in under a minute: bit.ly/3QUZRl5 Not every sequencing project starts in the same place. Answer 3 quick questions about your specific research goals, and we'll match you to a personalized resource bundle for your work in ~45 seconds.
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PacBio @pacbio.bsky.social · 03/08/2026
Get free access to the PacBio Rapid HiFi WGS Resource Bundle. In NICU settings, rapid WGS delivers critical answers for rare disease research when every hour counts. Get our technical note, ESHG poster, app note, and blog to see how to get variant calls in under 30 hrs: bit.ly/4eYvYIp
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PacBio @pacbio.bsky.social · 30/07/2026
When does long-range PCR make sense for targeted HiFi sequencing? If your target amplifies cleanly, LR-PCR is a simple, cost-effective way to preserve haplotype context. Read our blog to explore where it fits into targeted workflows and get practical assay design tips: bit.ly/4xaKOTF
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The practical value of long-range PCR for targeted HiFi sequencing - PacBio
Targeted workflow combines PCR-based enrichment with the accuracy, read length, and haplotype resolution of PacBio HiFi reads.
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PacBio @pacbio.bsky.social · 30/07/2026
Register for our upcoming webinar on long-read multiomics for human disease research! Hear three leading experts share how integrating genomics, transcriptomics, and proteogenomics advances rare disease and biopharma discovery. Save your spot today: bit.ly/4h4MGJ4 #PacBio #Multiomics
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PacBio @pacbio.bsky.social · 29/07/2026
Back by popular demand! Access one of our most-watched sessions on solving rare disease cases with HiFi sequencing. Get expert real-world cohort stories plus instant bonus access to our newest white paper on solve rates. Watch & download the whitepaper: bit.ly/4p4ZelG
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