iiinova — where your digital self keeps evolving

Reposted by Debby Silver

Development @dev-journal.bsky.social · 19/09/2026

Development is at the heart of our community, created by scientists for scientists. The leading #devbio journal for over 70 years, Development covers a broad range of in vivo research organisms and in vitro systems. See more reasons to publish:

journals.biologists.com

Reasons to publish in Development | Development | The Company of Biologists

Reasons to publish in Development | Development | The Company of Biologists Reasons to publish in Development Development is more than just a journal - we are part of your community. Published by a…

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Reposted by Debby Silver

Development @dev-journal.bsky.social · 26/05/2026

The choreography of development: RNA localization across time and space Chia-Fang Lee, @flydrbnl.bsky.social & @debbysilver.bsky.social highlight developmental roles for RNA localisation in cell polarity, fate and function across model organisms. journals.biologists.com/dev/article/...

mRNA localization impacts embryonic patterning and fate specification. mRNA localization dictates embryonic patterning, cell polarity and fate specification across diverse species, with examples shown. (A) In Saccharomyces cerevisiae, Ash1 mRNA is preferentially inherited by the daughter cell, which suppresses mating-type switching via HO endonuclease, influencing cell fate. (B) In Caenorhabditis elegans AB cells, mRNAs are translationally repressed and sequestered in P-granules into the P1 cell for specification of somatic and germline cells. (C) Xenopus laevis oocytes sequester mRNAs (e.g. nanos1, dazl and gdf1) to promote specification of the vegetal pole. (D) Drosophila melanogaster oocytes require localization of grk, bcd, osk and nos mRNAs for patterning of the anterior-posterior (A-P) and dorsal-ventral (D-V) axes. (E) The intestinal epithelium of mouse requires localization of rRNAs and mRNAs for increased translation efficiency and nutrient absorption upon feeding.

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Debby Silver @debbysilver.bsky.social · 10/06/2026

What a fantastic visit I had. Thanks so much @martinowk.bsky.social for hosting me and excited for future collaborations!

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Reposted by Debby Silver

James Briscoe @jamesbriscoe.bsky.social · 13/01/2026

There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking journals.biologists.com/dev/pages/pi...

journals.biologists.com

Pathway to Independence programme | Development | The Company of Biologists

Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...

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Reposted by Debby Silver

Matthew L. Kraushar @matthewkraushar.bsky.social · 19/11/2025

heads up neuro bsky 😎 must-read seminal discoveries: ultimate translation of genetic information in the farthest reaches of the neuron ➡️ @erin-schuman.bsky.social & in cortex development ➡️ @debbysilver.bsky.social thanks again 🤝 @natrevneuro.nature.com Darran Yates for editorial collaboration

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Reposted by Debby Silver

Cajal Club @cajalclub.bsky.social · 15/11/2025

At Sfn? Join us at the Cajal Club Social! Sunday, Nov. 16th, 6:30PM–8:30PM. Salt & Whiskey bar@Horton Grand Hotel, www.hortongrand.com/dine-bar. We will learn about an exhibition on Cajal's Work and give out this year's awards to outstanding trainees and established scientists in our community!

hortongrand.com

Salt & Whiskey - Horton Grand Hotel

Serving elevated comfort foods and classic handcrafted cocktails, Salt & Whiskey at the Horton Grand Hotel pays homage to grandeur of the Victorian era.

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Debby Silver @debbysilver.bsky.social · 10/10/2025

I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...

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Debby Silver @debbysilver.bsky.social · 13/09/2025

Thanks @blibep.bsky.social for hosting me in Marseille and sharing your exciting science on cerebellar evolution!! Thanks as well to @alexbaffet.bsky.social and @sbaulac.bsky.social for hosting me in Paris!! What a treat to visit with and discuss fantastic science with all! #internationalscience!

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MPI for Biological Intelligence @mpiforbi.bsky.social · 11/09/2025

From RNA to evolution: Come join our next keynote lecture on the choreography of brain development by @debbysilver.bsky.social, Professor at Duke University! 📍September 15 at 11am in NQ105 in Martinsried Art by @somedonkey.bsky.social

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Reposted by Debby Silver

Carolyn Johnson @carolynyjohnson.bsky.social · 18/08/2025

"What I would simply say is cancer can't wait." --Richard Schlueter, a 56-year-old metastatic cancer patient whose therapy was delayed due to terminations at NIH.

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Debby Silver @debbysilver.bsky.social · 10/08/2025

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

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Reposted by Debby Silver

Nature @nature.com · 14/05/2025

Taking a snippet of genetic code that is unique to humans and inserting it into mice helps them grow bigger brains than usual go.nature.com/3GOTQkz

go.nature.com

Mice grow bigger brains when given this stretch of human DNA

Finding adds to the bigger picture of how humans developed such large brains.

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Debby Silver @debbysilver.bsky.social · 14/05/2025

Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...

nature.com

A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature

HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...

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Mariah Hoye @mariahhoye.bsky.social · 10/04/2025

Re-amplifying this webinar! #metasci #neuroscience #science This would also be a great opportunity for early-career scientists to learn more about the prize and consider submitting an entry for the NINDS Early-Career Rigor Champions Prize (deadline 5/2/25)! www.challenge.gov?challenge=ni...

challenge.gov

Challenge.gov

Challenge.gov is the official government website supporting prize challenges and prize competitions that are sponsored by the US federal government. Here federal agencies provide prize awards to publi...

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Reposted by Debby Silver

Carl Zimmer @carlzimmer.com · 01/04/2025

"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?

nature.com

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs

In shock move, four institute directors at the US biomedical agency are removed from their posts.

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Pam Herd @pamherd.bsky.social · 30/03/2025

Trump has cut the NIH budget by more than half in defiance of Congressionally mandated appropriations for the agency. No comparison historically, not even the Great Recession. This is clearly not legal and Congress needs to address it.

Graph from the Washington Post showing declines in spending at NIH. New grants cut from 1 billion to around 400 million. Overall grants down from 4.5 billion to 2.4 billion.

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David Tobin @tobinlab.bsky.social · 08/03/2025

Inspiring speakers highlighting the importance to our collective health as well as economic return on investment of basic, curiosity-driven research at yesterday’s @standupforscience.bsky.social Frightening to see active dismantling of decades of public investments in our health and futures.

Itai Yanai speaking in front of thousands of participants at the Stand Up for Science event in front of the Lincoln Memorial in Washington, D.C.

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Rick Huganir @rhuganir.bsky.social · 15/02/2025

I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all. time.com/7216299/nih-...

time.com

Experts Call NIH Budget Cuts an 'Apocalypse' for Science

The reductions target indirect costs that cover administrative and equipment costs.

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Alt National Park Service @altnps.bsky.social · 15/02/2025

Don’t lose hope. Remember, Watergate took over two years to fully unravel from the initial break-in to Nixon’s resignation. Just like then and now, Americans are losing faith in their government. We are documenting every illegal action and will hold this administration and Elon Musk accountable.

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@LaBonneLaB @labonnelab.bsky.social · 11/02/2025

Our values and resolve are only strengthened by recent events.

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Sen. Adam Schiff @schiff.senate.gov · 08/02/2025

Trump & Musk are making massive cuts to the National Institutes of Health. I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.

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Reposted by Debby Silver

Seth Blackshaw @sethblackshaw.bsky.social · 08/02/2025

To my friends and colleagues at UAB, IU, UF, FSU, UL, WashU, OSU, CWRU, etc, etc. Call both your senators and your representative. They listen. Emphasize the direct economic impact of NIH research, and the indirect impacts on pharmaceutical/biotech. Underscore its relevance to national security.

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Bita Moghaddam @bita137.bsky.social · 28/01/2025

OMB memo tonight “Temporary Pause of Agency Grant, Loan, and Other Financial Assistance”

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Katie Mack @astrokatie.com · 28/01/2025

I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service. “Pausing” grants means people don’t eat.

washingtonpost.com

White House pauses all federal grants, sparking confusion

The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.

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Ardem Patapoutian @ardemp.bskyverified.social · 09/12/2024

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

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Carl T. Bergstrom @carlbergstrom.com · 23/01/2025

Today the Trump admin abruptly and indefinitely terminated many of the activities of the National Institutes of Health, the $50B/year collection of agencies that power the US biotech and health ecosystems. Even if these orders were lifted tomorrow, the disruption would be enormous. Why care? 🧵

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Debby Silver @debbysilver.bsky.social · 23/01/2025

Happy to share some good news today, and our latest study on DDX3X! Led by super talented @federicamosti.bsky.social we use live imaging, transcriptomics and interaction studies to define how clinically diverse missense mutations in DDX3X influence neural development. dx.plos.org/10.1371/jour...

dx.plos.org

Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations

Author summary DDX3X mutations are associated with neurodevelopmental disorders, including DDX3X syndrome and autism spectrum disorder. DDX3X is an RNA binding protein whose loss of function impairs b...

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the Node @the-node.bsky.social · 27/12/2024

📢Vote for the 2024 Development cover image of the year @dev-journal.bsky.social featured 24 cover images in 2024. Now is the chance to pick your favourite! Browse through the images and vote by 13 Jan: thenode.biologists.com/vote-for-the… #DevBio

Collage of the 24 Development cover images in 2024

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Reposted by Debby Silver

Development @dev-journal.bsky.social · 02/12/2024

Delighted to announce a new call for applications for our Pathway to Independence programme. Now entering its third year, this scheme supports postdocs going on the job market in 2025 - with training, mentorship, profile-raising and networking opportunities. Application deadline 31 Jan 2025. 1/3

journals.biologists.com

PI programme | Development | The Company of Biologists

PI programme | Development | The Company of Biologists Development's Pathway to Independence programme Development is excited to announce our call for our Pathway to Independence program...

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Debby Silver @debbysilver.bsky.social · 02/12/2024

Please consider sending your next paper to Development! (As an editor I can attest to below.)

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turrigiano.bsky.social @turrigiano.bsky.social · 01/12/2024

If you live in a red state, now is a good time to call or write your senators and ask them to stand by NIH and oppose the confirmation of RFK and Bhattacharya🧪. If you live in a blue state do it as well! We need to galvanize opposition to the wrecking ball approach to reform

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Development @dev-journal.bsky.social · 26/11/2024

Welcome to Development's Bluesky account 🧪 Development is a leading primary research journal in developmental and stem cell biology, published by The Company of Biologists @biologists.bsky.social, a not-for-profit organisation, and edited by expert researchers in the #DevBio field.

journals.biologists.com

Development | The Company of Biologists

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Jeremy Berg @jeremymberg.bsky.social · 22/11/2024

PIONEERS When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities. 1/n www.science.org/content/arti...

science.org

NIH's Roadmap to the Future

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Debby Silver @debbysilver.bsky.social · 16/11/2024

Happy to be on Bluesky! Our lab is fascinated by how the brain develops, how this goes awry in disease, and this is co-opted in evolution. A major focus is dynamic spatial and temporal #RNA control in the developing brain. Please see our new review on evolution! www.sciencedirect.com/science/arti...

sciencedirect.com

How our brains are built: emerging approaches to understand human-specific features

Understanding what makes us uniquely human is a long-standing question permeating fields from genomics, neuroscience, and developmental biology to med…

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Alex Eve @amjeve.uk · 14/11/2024

Developmental processes don't just occur in the embryo! Development's (@biologists.bsky.social) next Special Issue - Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues. Papers: 15 May 2025. #devbio #regeneration #stemcells journals.biologists.com/dev/pages/li...

journals.biologists.com

CFP | Lifelong Development | Development | The Company of Biologists

CFP | Lifelong Development | Development | The Company of Biologists Special Issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Development invites yo...

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