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Daianna Gonzalez Padilla

@daiannaglez.bsky.social
286 followers 75 following 0 posts

Biostats and Human Genomics 🧬🧮. BS LCG-UNAM 🇲🇽 Researcher at the MRC Biostatistics Unit, University of Cambridge

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Reposted by Daianna Gonzalez Padilla
Isaac García @isaacgs94.bsky.social · 16/05/2025
It's finally out people ✅🗞️! Check out the final version of our work exploring factors influencing the germline mutation rate and spectra on ~10,000 WGS family trios 🧬👨‍👩‍👦! www.nature.com/articles/s41...
nature.com
The impact of ancestral, genetic, and environmental influences on germline de novo mutation rates and spectra - Nature Communications
Here the authors analyze de novo mutations in >10,000 parent-offspring trios and find that ancestry and smoking independently associate with mutation rate, but that common genetic variants likely c...
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Reposted by Daianna Gonzalez Padilla
Louise Huuki-Myers @lahuuki.bsky.social · 11/04/2025
Hey #deconvolution fans! 👀 We’ve got an exciting new publication for you: a benchmark of 6 popular deconvolution methods on a multimodal human brain #DLPFC dataset 🧠🧬 Now out in Genome Biology: doi.org/10.1186/s130... @lieberinstitute.bsky.social @jhubiostat.bsky.social
doi.org
Benchmark of cellular deconvolution methods using a multi-assay dataset from postmortem human prefrontal cortex - Genome Biology
Cellular deconvolution of bulk RNA-sequencing data using single cell/nuclei RNA-seq reference data is an important strategy for estimating cell type composition in heterogeneous tissues, such as the h...
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