iiinova — where your digital self keeps evolving

Reposted by Heena Divecha

Keri Martinowich @martinowk.bsky.social · 31/10/2025

Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.

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Reposted by Heena Divecha

Keri Martinowich @martinowk.bsky.social · 24/10/2025

For #FluorescenceFriday - projection neurons from the mouse prefrontal cortex to the locus coeruleus 🔴 with Fos labeling activated cells 🟢. Image credit to the Circuits team in the Translational Neuroscience Division @lieberinstitute.bsky.social 🧠🔬🧪

Image captured at 4X on a fluorescence microscope showing a tissue section through the mouse prefrontal cortex where neurons that project to the locus coeruleus in the brainstem are virally labeled in red and neurons that are activated are labeled with Fos in green.

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Heena Divecha @heenadivecha.bsky.social · 26/09/2025

For #FluorescenceFriday✨ Exploring the beauty of the locus Coeruleus using IF staining: neurons🔵 surrounded by glowing astrocytes🟢 embracing delicate blood vessels🔴, alongside striking pTau signals💗. A vivid reminder of the cellular complexity shaping brain health and disease. #LC #Neuroscience

Here’s my Fluorescence Friday highlight: just got this beautiful shot from the locus coeruleus in our latest tissue section! You can see astrocytes (in green) glowing and wrapping around tiny blood vessels (in red), with pTau staining (in magenta) lighting up the scene. It’s wild how much is going on in just one microscopic field—so cool to see these markers all together and think about what they mean for brain health and Alzheimer’s research. Loving the chance to peek into these cellular hangouts each week! #FluorescenceFriday #PhDLife #Neuroscience

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Reposted by Heena Divecha

Keri Martinowich @martinowk.bsky.social · 01/08/2025

For #FluorescenceFriday - dorsomedial prefrontal cortex in human 🧠 staining blood vessels 🔴, astrocytes🟠, and neurons 🟣 as part of testing our new Akoya PhenoImager - exciting addition to the @lieberinstitute.bsky.social Microscopy and Spatial Biology Core. Image credit to @heenadivecha.bsky.social

Section of tissue of human brain staining astrocytes, blood vessels and neurons

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Heena Divecha @heenadivecha.bsky.social · 09/06/2025

🎨 Struggling to pick the perfect color palette for data visualizations? Check out walkthrough of interactive tools and the awesome {paletteer} package by @emilhvitfeldt.bsky.social ! 🔗 youtu.be/9tAeTjVD7ns Let’s make our plots both beautiful and accessible! #RStats @libdrstats.bsky.social

youtu.be

Choosing a Color Palette

YouTube video by Leonardo Collado Torres

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