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Markus Meister

@mameister4.bsky.social
3.8K followers 204 following 196 posts

Neuroscientist. Long-form opinions at markusmeister.com.

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Reposted by Markus Meister
Jieyu Zheng @jieyusz.bsky.social · 04/09/2026
How fast can mice learn complex mazes? With @mameister4.bsky.social we reveal memory, generalization, latent learning, and remote credit assignment of mice in the Manhattan Maze. Do mice born without a cortex or hippocampus have them too? Check it out! www.biorxiv.org/content/10.6...
biorxiv.org
Rapid spatial cognition in mice, with and without neocortex and hippocampus
Rapid learning, memory, and generalization are often attributed to circuits of the neocortex and hippocampus, but their specific role remains unclear. To examine these cognitive abilities together in ...
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Markus Meister @mameister4.bsky.social · 10/06/2026
Really enjoyed reading this! Takes on some weighty issues – scientific integrity, fate of the world,... – through the eyes of an enthusiastic 17-y old. Who ended up changing his university before Christmas of his freshman year.
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Markus Meister @mameister4.bsky.social · 27/04/2026
Why should the functions of the brain be understandable by humans? It's worth remembering that the human mind is a pitifully limited instrument for cognition. More arguments here: disq.us/p/35lqqzn
disq.us
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Markus Meister @mameister4.bsky.social · 20/03/2026
Amazing new data set from Yeon Jin Kim and colleagues with the connectome of a human fovea: www.biorxiv.org/content/10.1...
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Markus Meister @mameister4.bsky.social · 20/03/2026
Cool new work from Wiederhold and colleagues, analyzing the speed of mental processing during mental calculations like this one: www.youtube.com/watch?v=JawF... Open review in the comments. www.biorxiv.org/content/10.1...
youtube.com
Mental Arithmetic World Champion - Flash Anzan
YouTube video by Mega Hafıza
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Markus Meister @mameister4.bsky.social · 19/03/2026
Just a reminder that we can do peer review without publishers. disq.us/p/35bbdxl disq.us/p/35b9ay8 meisterlab.caltech.edu/markusmeiste...
disq.us
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Markus Meister @mameister4.bsky.social · 27/12/2025
Really enjoyed this story about maintaining your sailboat (and your sanity). "Sometimes maintenance involves shooting the shark." books.worksinprogress.co/book/mainten...
books.worksinprogress.co
The Maintenance Race - Seventh Draft | Books in Progress
Books in Progress is what we call a “public drafting tool”: Drafts will be made available for comment from the public, allowing for direct collaboration between author and reader.
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Markus Meister @mameister4.bsky.social · 21/12/2025
@erictopol.bsky.social posted this diagram earlier today. When I pointed out the obvious AI slop and copious errors, he blocked me. But you can also find it on his substack. Topol poses as a serious medical person, but disseminating such graphical nonsense is disqualifying. Unfollow.
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Reposted by Markus Meister
Dinu F Albeanu @dinanthos.bsky.social · 15/12/2025
Adam Kampff’s passion for understanding and explaining the world was unmatched. Living by example and not ever compromising on his dreams, Adam was uncanny in making people realize they can learn and understand anything and everything. Keep his dream alive! In his own words: tinyurl.com/ye29csw3
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Markus Meister @mameister4.bsky.social · 21/11/2025
Come on Konrad, why do you cave so easily? Here, let me try it for you: 1. Spikes are (to good approximation) the only events that matter. 2. Extracellular fields are one way by which spikes interact with each other. 1/2
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Markus Meister @mameister4.bsky.social · 20/11/2025
Observed at an SfN poster session?
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Reposted by Markus Meister
Daniel Pollak @danielpollak.bsky.social · 17/11/2025
#SfN25 's hottest club is Poster X8 Tuesday Morning. This club has everything: mice hunting robotic bait, quantitative behavior modeling, chronic superior colliculus Neuropixel data, and GLM encoding/decoding, not to mention the cheap new DAQ EVERYONE's been rumbling about. See you there!
Poster X8 on Tuesday morning, 8-12
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Markus Meister @mameister4.bsky.social · 16/11/2025
If you are looking for a postdoc with interests in animal cognition and behavior, be sure to talk to Jieyu Zheng: you won't regret it!
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Markus Meister @mameister4.bsky.social · 07/11/2025
That image is from 1961 and an idealization. Here is an actual trajectory of fixational eye movements. The dots are 2 ms apart. If a midget ganglion cell, with single-cone receptive field, fires at 100 Hz, then every spike reports about a different cone. How can we ever read anything?
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Markus Meister @mameister4.bsky.social · 03/11/2025
That's nothing! The US, as we know, is an agrarian economy, optimized for growing soybeans exported to China. The yearly production of soybean seeds, if placed end to end, forms a chain of beads 10^10 km long: the distance from the Sun to Pluto and back. It streams at about 0.1% the speed of light.
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Markus Meister @mameister4.bsky.social · 22/09/2025
Sure, China has invented the future, with innovations like high-speed trains and all-electric traffic. But no-one talks about the Jim Beam Soda Fountain! Dispenses everything from straight Bourbon to 3 different cocktails. Beating Kentucky at its own game...
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Markus Meister @mameister4.bsky.social · 15/09/2025
Human intelligence is overrated and not a useful yardstick for AI - a polemic. markusmeister.com/2025/09/15/w...
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Markus Meister @mameister4.bsky.social · 08/08/2025
What a cool public science project! www.nytimes.com/2025/08/08/w...
nytimes.com
A Starfish, a President and a Deep-Sea Frenzy in Argentina
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Markus Meister @mameister4.bsky.social · 30/07/2025
I learned a lot from reading this book on climate science: "Unsettled?" by Steven E. Koonin. Sure, it comes from a contrarian perspective, but it's quantitative, well-sourced, and nuanced in its critique. Lots of useful pointers to go explore the primary literature.
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Reposted by Markus Meister
adamezracohen.bsky.social @adamezracohen.bsky.social · 28/05/2025
I wrote about the government's attacks on Harvard. Hope this reaches a few persuadable minds. prosyn.org/PhWi74r?h=Ky...
prosyn.org
Defunding Harvard Hurts America | by Adam Ezra Cohen - Project Syndicate
Adam Ezra Cohen explains the real-world consequences of canceling federal research grants in the name of fighting antisemitism.
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Markus Meister @mameister4.bsky.social · 21/05/2025
If you're planning a course with mathematical methods content, or use such methods in your own work, please take a look at "Mathematics in Biology", by Meister, Lee, and Portugues, published at MIT Press. 1/2 @portugueslab.bsky.social mitpress.mit.edu/978026204940...
mitpress.mit.edu
Mathematics in Biology
Biology has turned into a quantitative science. The core problems in the life sciences today involve complex systems that require mathematical expression, ye...
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Markus Meister @mameister4.bsky.social · 02/05/2025
A sobering assessment of consciousness studies from Hakwan Lau: "the label ’consciousness’ may eventually serve little other function but to signal that the associated studies are subpar and overinterpreted compared to mainstream cognitive neuroscience research"
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Markus Meister @mameister4.bsky.social · 26/03/2025
I'm with David Sussillo's critique here. If you want answers you have to ask concrete questions. Black-box modelling of huge data volumes won't get you any closer.
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Markus Meister @mameister4.bsky.social · 20/02/2025
Here it is finally: Our mathematical methods book for life scientists! Aimed at advanced undergrads and beginning grad students, plus all those who want a deeper look at the math behind quantitative biology. @portugueslab.bsky.social. 1/3
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Carl Zimmer @carlzimmer.com · 26/12/2024
I wrote about a scientific paper called “The Unbearable Slowness of Being” which finds that the human brain’s throughput is just 10 bits per second. Gift link: www.nytimes.com/2024/12/26/s... 🧪
nytimes.com
Human Thought Is Far Slower Than Your Internet Connection (Gift Article)
A new study is “a bit of a counterweight to the endless hyperbole about how incredibly complex and powerful the human brain is,” one researcher said.
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Reposted by Markus Meister
The Transmitter @thetransmitter.bsky.social · 17/12/2024
"[It’s] the largest unexplained number in brain science. I feel like neuroscience should pay more attention to it ..." said Marcus Meister when @claudia-lopez.bsky.social sat down with him and @jieyusz.bsky.social for a Q&A about the brain's information-processing rate. #neuroskyence bit.ly/3ZXxWTf
bit.ly
Explaining ‘the largest unexplained number in brain science’: Q&A with Markus Meister and Jieyu Zheng
The human brain takes in sensory information roughly 100 million times faster than it can respond. Neuroscientists need to explore this perceptual paradox to better understand the limits of the brain…
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Markus Meister @mameister4.bsky.social · 17/12/2024
The unbearable slowness of being: Humans still clock in at just 10 bits/s. Even after peer review :) Share link: authors.elsevier.com/a/1kHVa3BtfH.... ArXiv: arxiv.org/abs/2408.10234
authors.elsevier.com
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Markus Meister @mameister4.bsky.social · 15/12/2024
After being gifted the most magical computing device on the planet, humans use it to organize more vicious fist fights. Does anyone still think that human intelligence is a useful milestone on the way to machine intelligence? www.nytimes.com/2024/12/15/t... #NeuroAI
nytimes.com
How Student Phones and Social Media Are Fueling Fights in Schools
Cafeteria melees. Students kicked in the head. Injured educators. Technology is stoking cycles of violence in schools across the United States.
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Markus Meister @mameister4.bsky.social · 14/12/2024
Horace Barlow, by all accounts, was thinking about 30 years ahead of his time. Here is a transcript of the opening keynote I gave at a symposium honoring Horace's scientific legacy: markusmeister.com/2024/12/14/h....
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Markus Meister @mameister4.bsky.social · 12/12/2024
If you're a student interested in quantitative life science, and you don't have this book on your shelf yet, this is the best time to correct that!
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Reposted by Markus Meister
Steven Strogatz @stevenstrogatz.com · 16/01/2024
The third edition of my textbook, Nonlinear Dynamics and Chaos, was published today. You can preview the first 68 pages on Google Books, or take a look at the preface below to see what's new. The main new thing is a chapter on the Kuramoto model! Hope you enjoy it.
book cover and first page of the preface
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Markus Meister @mameister4.bsky.social · 14/11/2024
Have you had private doubts whether we'll ever understand the brain? Whether we'll be able explain psychological phenomena in an exhaustive way that ranges from molecules to membranes to synapses to cells to cell types to circuits to computation to perception and behavior?
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Markus Meister @mameister4.bsky.social · 11/09/2024
Flying Lufthansa during the presidential debate. We’re told that “unfortunately” the WiFi is broken. Clever move to ensure a peaceful flight.
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Markus Meister @mameister4.bsky.social · 11/09/2024
From my file of "papers that keep on giving", this beautiful review from Mike Land on eye movements in everyday life: pubmed.ncbi.nlm.nih.gov/16516530/. I read this back when, but came across it again now with different needs, and learned a whole set of orthogonal things.
pubmed.ncbi.nlm.nih.gov
Eye movements and the control of actions in everyday life - PubMed
The patterns of eye movement that accompany static activities such as reading have been studied since the early 1900s, but it is only since head-mounted eye trackers became available in the 1980s that...
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Markus Meister @mameister4.bsky.social · 21/08/2024
Why is reality so slow? Why can we only have one thought at a time? Why do we need so many neurons? Will Elon Musk's Neuralink really speed up his cognition? For answers and more questions check out our new review: "The Unbearable Slowness of Being". arxiv.org/abs/2408.10234
arxiv.org
The Unbearable Slowness of Being
This article is about the neural conundrum behind the slowness of human behavior. The information throughput of a human being is about 10 bits/s. In comparison, our sensory systems gather data at...
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Markus Meister @mameister4.bsky.social · 04/08/2024
Are you going to #CCN2024? And are you ready to question your beliefs about rodent hippocampus and cortex? Then see the talk and poster by Jieyu Zheng and Rogerio Guimaraes. Details: jieyusz.github.io/publication/...
jieyusz.github.io
Mice in the Manhattan Maze: Rapid Learning, Flexible Routing and Generalization, With and Without Cortex
My main project, using a novel tool to study complex cognition in mice and the role of cortex!
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Markus Meister @mameister4.bsky.social · 17/03/2024
A few days ago, the journal eLife published a self-study on the first year of its new publishing model, and it is well worth a look. Here are some notes based on my own experience with the journal as author and reviewing editor: markusmeister.com/2024/03/17/a....
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Markus Meister @mameister4.bsky.social · 14/10/2023
Guilty pleasure last week: watching "Beckham" on Netflix. Lots of unexpected insights! Trigger warning for England fans: features the "hand of god" goal.
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Markus Meister @mameister4.bsky.social · 13/10/2023
Got to experience general anesthesia again today. What a miracle! From "lights on" to "lights out" and back, both transitions were instantaneous. These methods have improved so much since I got tonsils out as a kid.
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Markus Meister @mameister4.bsky.social · 12/10/2023
Saw a fantastic art documentary yesterday: "Anselm" by Wim Wenders. The scale of the ambition and accomplishment here is stunning.
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