People increasingly use large language models (LLMs) to explore ideas, gather information, and make sense of the world. In these interactions, they encounter agents that are overly agreeable. We argue...

Why simple models keep winning, where deep learning still shines, and where the field is headed

53% of academics show signs of depression. This is a role design failure, not a resilience issue: we are managing 21st-century experts with medieval guild structures. To fix the crisis, we must abando...

El hallazgo revela que la resistencia microbiana evolucionó de forma natural mucho antes del uso clínico de fármaco y alerta sobre el riesgo de que el deshielo libere estos genes

Living at high altitude appears to protect against diabetes, and scientists have finally discovered the reason. When oxygen levels drop, red blood cells switch into a new metabolic mode and absorb lar...

Abstract. Microbial communities are structured through complex interactions that are difficult to observe directly. Co-occurrence networks offer a way to i

In a university ecosystem that breeds hunger for status, Epstein made scholars feel like celebrities

Researchers at the Johns Hopkins Kimmel Cancer Center have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key…

Abstract The crisis of antimicrobial resistance (AMR) is escalating while the antibiotic pipeline remains stagnant. Our bibliometric analysis of eight decades of literature reveals a critical imbalanc...

Shibl et al. conduct a comprehensive multi-omics analysis of the oral microbiome in obesity, revealing distinct microbial and metabolic profiles. Obese individuals show enrichment of proinflammatory, ...

Abstract. Most microbes grow in spatially structured communities, and this profoundly shapes their ecology and evolution. At the microscale, short interact

Silva et al. perform a global analysis of over 11,000 gut microbiomes and reveal that uncultured bacteria are key markers of gut health. The uncultured genus CAG-170 is strongly linked to low gut dysb...

This volume is Open Access. This volume details protocols for sampling and analysis microbiomes from sites other than the gut.

Published in Computational biology and chemistry

Human genetic loci that associate with composition of the oral microbiome are identified using saliva-derived DNA, where the same host genetics also shapes oral health and genetic variation in oral bacteria.

Background The role of gut microbiome in predicting diet response and developing personalized dietary recommendations has been increasingly recognized. Yet, we still lack comprehensive, genome-based i...

Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic ele...

Founded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, an...

Scientific Reports - Microbiome analysis and confocal microscopy of used kitchen sponges reveal massive colonization by Acinetobacter, Moraxella and Chryseobacterium species

💬 0  🔁 0  ❤️ 0 · My paper, "Preparation of Cuvette-Based Sorters for Sorting Submicron Microbial Cells and Viruses from Environmental and Biological Samples," has been published in Current Protocol…

Researchers detected Pseudomonas aeruginosa, a common hospital-acquired bacterium, often found in moist environments. But this strain carried a gene called New Delhi metallo-β-lactamase (NDM-1), an en...

This protocol set focuses on the preparation of the BD FACSAria II/III/Fusion, a cuvette-based cell sorting system commonly found in shared resource settings, to sort submicron samples, including but...

Nature Reviews Genetics - In this Review, Roux and Coclet outline current viromics approaches and discuss how they have contributed to our growing understanding of viral genomic diversity, focusing...

Bacterial diversity can be overwhelming. There is an ever-expanding number of bacterial taxa being discovered, but many of these taxa remain uncharacterized with unknown traits and environmental prefe...

Bacterial resistance to chlorine disinfectant reduces its effectiveness in killing pathogenic bacteria and poses a severe threat to environmental and health safety. The interaction between bacteria and phages is the most frequent biological activity in Earth's biosphere, but little is known about wh …

In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.

When hunter-gatherers began living close to animals, the pathogens that cause the plague and leprosy got closer too.