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Jaime Martinez-Urtaza

@jaimemurtaza.bsky.social
111 followers 296 following 9 posts

(Meta)genomics & evolution of human pathogens. Global health in a planet facing a climate emergency. All opinions are mine. Professor of Genetics at the Universitat Autònoma de Barcelona

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Reposted by Jaime Martinez-Urtaza
Molecular Biology and Evolution @molbioevol.bsky.social · 16/12/2025
To address uncertainty in model choice for reconstructing population history, Xu, @alexeidrummond.bsky.social et al. introduce a new Bayesian model averaging (BMA) framework. 🔗 doi.org/10.1093/molbev/msaf297 #evobio #molbio #compbio
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Reposted by Jaime Martinez-Urtaza
Alexei Drummond @alexeidrummond.bsky.social · 28/07/2026
Get excited :) PhyloSpec is coming! A shared standard + modelling language for phylogenetic models. Write a model once, run it across engines like BEAST X, BEAST 2.8 & RevBayes. Easy and reproducible. Built by @tochsner.bsky.social & collaborators (ETH Zürich, Auckland, LMU). phylospec.com
phylospec.com
PhyloSpec
A standardized way to describe phylogenetic model components, common assumptions, and best practices in the field of phylogenetics.
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Reposted by Jaime Martinez-Urtaza
alex jaffe @alexjaf.bsky.social · 21/07/2026
my first 'data descriptor'! hoping this one will be useful for folks interested in tracing the distribution of genomes/genes/proteins over physicochemical gradients in the (deep) marine water column.
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Reposted by Jaime Martinez-Urtaza
Cameron Thrash @jcamthrash.bsky.social · 01/04/2026
Deciphering the Hidden Ecology and Connectivity of Vibrio in the Oceans www.nature.com/articles/s41... #jcampubs 🌊
nature.com
Deciphering the Hidden Ecology and Connectivity of Vibrio in the Oceans - Nature Communications
Marine bacteria Vibrio are emerging pathogens worldwide, yet their global dispersal is poorly understood. Combining metagenomic and ocean drifter data, authors show Vibrio dispersal across oceans, con...
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Marie-Eve VAL @val-meve.bsky.social · 04/05/2026
We first took a broad comparative-genomics approach, updating the map of ERs across bacterial diversity by analyzing >40,000 complete genomes. Large ERs tend to converge in GC content toward their host chromosome, recur independently, and are often conserved at the genus level.
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Nature @nature.com · 28/04/2026
Nature research paper: Decade-long warming accelerates antibiotic resistance in grassland soils go.nature.com/4cCPhG1
go.nature.com
Decade-long warming accelerates antibiotic resistance in grassland soils - Nature
Decade-long warming increased soil antibiotic-resistance genes by about 24%, enriching resistant microbes and gene transfer, driven by selection for thermal tolerance and linked traits, with implications for public health.
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Reposted by Jaime Martinez-Urtaza
Lancet Countdown Europe @countdowneurope.bsky.social · 22/04/2026
📣 New publication: the 2026 Europe report of the Lancet Countdown is out! The report shows how climate change is already harming health across Europe, how fossil fuel dependence is slowing progress, and why stronger leadership is urgently needed. Read the full report: doi.org/10.1016/S246...
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Reposted by Jaime Martinez-Urtaza
Bioinformatics Advances @bioinfoadv.bsky.social · 13/03/2026
🧬 New in Bioinformatics Advances: "Memod-s: A standardised workflow to explore and analyse prokaryotic methylation patterns for Nanopore sequencing data"  Explore the study: doi.org/10.1093/bioadv/vbag072  Authors include: @alessiome.bsky.social, @jaimemurtaza.bsky.social
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Reposted by Jaime Martinez-Urtaza
eLife @elife.bsky.social · 04/01/2026
Bacteria swap DNA far more than we thought. This study shows recombination between species can blur genetic boundaries, with up to 95% of diversity coming from hybrid DNA in some microbes.
buff.ly
Remixing the gene pool
Microbes might behave less like distinct species and more like constantly interbreeding communities.
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Reposted by Jaime Martinez-Urtaza
Torsten Seemann @torstenseemann.bsky.social · 15/12/2025
💾 Prokka 1.15.6 is released! This is the last major release of Prokka. But don't be sad, because @oschwengers.bsky.social already has an excellent replacement called Bakta you can migrate to. #bioinformatics #microbiology #genomics github.com/tseemann/pro...
github.com
Release Heading into the sunset · tseemann/prokka
The future This is probably the last release of Prokka. I won't be making any code changes except bug fixes. I will update the databases occasionally. I strongly recommend you use Bakta by @oschwen...
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Reposted by Jaime Martinez-Urtaza
Brian D. Wade @astrobrian.bsky.social · 08/11/2025
Strain displacement in microbiomes via ecological competition #microbes #ecology #microSky www.nature.com/articles/s41...
nature.com
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
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Reposted by Jaime Martinez-Urtaza
eLife @elife.bsky.social · 02/11/2025
Hybridisation breaks species barriers in long-term coevolution of a cyanobacterial population. buff.ly/EaJskBA
Hybridization between previously isolated lineages is main source of diversity within the population.
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Reposted by Jaime Martinez-Urtaza
Nature Reviews Genetics @natrevgenet.nature.com · 30/10/2025
New online! From clonality to complexity: a journey through microbial ecology and evolution
nature.com
From clonality to complexity: a journey through microbial ecology and evolution
Nature Reviews Genetics, Published online: 30 October 2025; doi:10.1038/s41576-025-00910-6Jaime Martinez-Urtaza reflects on two papers by Smith et al., who found that bacteria exist along a continuum from clonal to recombining populations, and introduced the concept of an ‘epidemic’ microbial population structure.
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Reposted by Jaime Martinez-Urtaza
The Lancet Countdown on Health and Climate Change @lancetcountdown.bsky.social · 29/10/2025
🚨 JUST PUBLISHED 🚨 ⚠️ The 2025 @lancetcountdown.bsky.social report reveals climate change inaction is costing lives and livelihoods, and harming the economy. ❤️‍🩹 Protecting people’s health demands all hands on deck. Read more: www.lancetcountdown.org/2025-report/ #LancetClimate25
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Reposted by Jaime Martinez-Urtaza
Science Magazine @science.org · 17/10/2025
Bacteria undergo rapid genetic changes that are selected by alterations in the human gut environment. Learn more in a new #SciencePerspective: scim.ag/4qaRWNh
scim.ag
Natural directed evolution in gut microbiota
Bacteria undergo rapid genetic changes that are selected by alterations in the human gut environment
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Reposted by Jaime Martinez-Urtaza
Sarah Alexander @sarah1alexander.bsky.social · 25/09/2025
please read this thread - even if you don;t get time to read the paper!!!!! just the best - great work, really really great.
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Salvador Almagro-Moreno @bioetry.bsky.social · 18/09/2025
Delighted to announce that The International Meeting on the Biology of Vibrios will be back next year! Vibrio2026 will be held in Berlin in September 13-16. See you there Vibriologists! event.fourwaves.com/vibrio2026/p...
event.fourwaves.com
Vibrio2026: The International Meeting on the Biology of Vibrios
Fourwaves - Vibrio2026: The International Meeting on the Biology of Vibrios
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Colin Carlson @colincarlson.bsky.social · 17/09/2025
🚨 NEW: Climate change is already causing 30,000 deaths per year - a global annual economic loss of $100-350B USD - but the true damage is probably 10x higher. Out TODAY in Nature Climate Change: the first systematic look at the science of "health impact attribution" 🔓 www.nature.com/articles/s41...
"Health losses attributed to anthropogenic climate change," a brief communication in the journal Nature Climate Change. There's a map showing regions of the world, and pie charts of relevant studies as they apply to different health impacts like "heat-related deaths" and "maternal and child health"
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Chao Yang @chaooo.bsky.social · 27/08/2025
Our “Less is more” story is out! 🚀 We reveal how gene loss shaped the adaptive evolution of pandemic Vibrio parahaemolyticus, highlight a potentially general mechanism across bacteria. Huge thanks @danielfalush.bsky.social @campy-bara.bsky.social @jaimemurtaza.bsky.social & all coauthors
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Nature Ecology & Evolution @natecoevo.nature.com · 27/08/2025
Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide www.nature.com/articles/s41...
nature.com
Wave succession in the pandemic clone of Vibrio parahaemolyticus driven by gene loss - Nature Ecology & Evolution
A combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows that gene loss in the putrescine utilization pathway has enhanced biofilm formation an...
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Salvador Almagro-Moreno @bioetry.bsky.social · 27/08/2025
Beautiful work on the emergence of the pandemic clone of V. parahaemolyticus
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Martin Kuhlwilm @kuhlwilm.bsky.social · 24/07/2025
How to get introgressed fragments in genomic data? Everything you always wanted to know you find in our review in @cp-trendsgenetics.bsky.social, led by Xin Huang: doi.org/10.1016/j.ti...
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Reposted by Jaime Martinez-Urtaza
Andy Walton @andyjmwalton.bsky.social · 01/08/2025
Really excited to share the first paper from my PhD - it’s all about assumptions in modelling and the history of early population genetics… 🧵 doi.org/10.1111/ahg....
doi.org
The History of the Panmictic Population Concept and Its Legacy in Contemporary Population Genetics
ABSTRACT The panmictic population concept is at the heart of population, evolutionary and conservation genetics. However, in nature, true panmictic populations are vanishingly rare. As an idea conce...
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Reposted by Jaime Martinez-Urtaza
Molecular Biology and Evolution @molbioevol.bsky.social · 20/07/2025
Long et al. integrate population genomics, experimental evolution, and environmental modeling to elucidate the evolutionary responses to climate change in Populus lasiocarpa. This study has made the July cover of MBE. 🔗 doi.org/10.1093/molbev/msaf116 #evobio #molbio
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Sarah Svensson @campy-bara.bsky.social · 30/06/2025
Happy to share the preprint from here in Shanghai, together with @danielfalush.bsky.social, as well as with team Zhizhou Jia, Huqi Wen, and Zhe Xie! www.biorxiv.org/content/10.1...
biorxiv.org
Evolution of hunt, kill, devour in a Vibrio ecospecies
Bacterial ecospecies are a recently recognized genetic structure that is hypothesized to arise by complex adaptation to a new niche. Using coadaptation analysis as a foundation for laboratory experime...
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Javier Santoyo @jsantoyo.bsky.social · 01/07/2025
Cleanifier: A fast and lightweight k-mer based tool to remove contamination in microbial sequence data. #MicrobialSequences #ContaminationRemoval #Kmers #Genomics #Bioinformatics @biorxivpreprint www.biorxiv.org/content/10.1...
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Segata Lab @cibiocm.bsky.social · 03/06/2025
🥁NEW publication from our lab: the largest meta-analysis of gut microbiome associations with CRC! www.nature.com/articles/s41... 🧵⬇️ 1/6
nature.com
Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer - Nature Medicine
An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the ...
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Reposted by Jaime Martinez-Urtaza
Nature Microbiology @natmicrobiol.nature.com · 06/05/2025
🚨 Out now! Chronostrain - a method to profile low abundance strains in longitudinal microbiome samples 🦠💻 @travis.gibsonlab.io @younhk.bsky.social @gibsonlab.io @harvardmed.bsky.social @broadinstitute.org #MicroSky 🦠 #MicrobiomeSky www.nature.com/articles/s41...
nature.com
Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain - Nature Microbiology
ChronoStrain accurately profiles low-abundance strains in longitudinal samples by jointly modelling nucleotide sequencing errors, strain presence/absence and the temporal information associated with e...
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Reposted by Jaime Martinez-Urtaza
Ákos T Kovács @evolvedbiofilm.bsky.social · 17/05/2025
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution @natbiotech.nature.com from @microbiome.bsky.social www.nature.com/articles/s41...
nature.com
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution - Nature Biotechnology
The evolution of microbial strains is revealed by analyzing structural variation.
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Reposted by Jaime Martinez-Urtaza
Alexis Stamatakis @stamatak.bsky.social · 15/05/2025
RAxML-NG v2.0 beta is here github.com/amkozlov/rax... Features 1. Difficulty prediction academic.oup.com/mbe/article/... 2. Adaptive search academic.oup.com/mbe/article/... 3. Early Stop www.biorxiv.org/content/10.1... 4. Model selection 5. Rapid bootstrapping academic.oup.com/mbe/article/...
github.com
Release RAxML-NG v2.0-beta2 · amkozlov/raxml-ng
Main new features Adaptive tree search heuristic (Togkousidis 2023) , (Togkousidis 2024) Multiple fast branch support measures Integrated model testing Full Changelog: 1.2.2...2.0-beta2
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Reposted by Jaime Martinez-Urtaza
Nature Biotechnology @natbiotech.nature.com · 22/04/2025
Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - @lauraluebbert.com @lpachter.bsky.social go.nature.com/4lGrSY3
go.nature.com
Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes - Nature Biotechnology
A workflow using conserved amino acid domains identifies viruses in sequence data at single-cell resolution.
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Magdalena Skipper @magdalenaskipper.bsky.social · 24/04/2025
New genomic & genetic insights into Mendel’s pea genes, including previously uncharacterised alleles 159 years after Mendel published his work, this is a real delight (especially for a geneticist) 🧪 @nature.com www.nature.com/articles/s41...
nature.com
Genomic and genetic insights into Mendel’s pea genes - Nature
Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their m...
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Hasindu Gamaarachchi @hasindu2008.bsky.social · 19/04/2025
This new Hifiasm --ont option is amazing. It worked like a charm for us in the nanopore adaptive sampling based assembly paradigm we introduced in a preprint recently. www.biorxiv.org/content/10.1...
biorxiv.org
Adaptively integrated sequencing and assembly of near-complete genomes
Recent advances in long-read sequencing (LRS) and assembly algorithms have made it possible to create highly complete genome assemblies for humans, animals, plants and other eukaryotes. However, there...
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Zack Labe @zacklabe.com · 13/04/2025
Our rising seas. This is only going to get harder to ignore. This NASA visualization was created by svs.gsfc.nasa.gov/5520/
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Prof Ian Hall @ianhall.bsky.social · 13/04/2025
Ocean heat content (OHC) in 2024 Global full-depth OHC gain since 1960 reached a record 452 ± 77 zetajoules (ZJ) in 2024. OHC was 15 ± 9 ZJ higher than in 2023, primarily associated with warming in the Atlantic and Indian Oceans 1 ZJ = 1,000,000,000,000,000,000,000 J www.nature.com/articles/s43...
nature.com
Ocean heat content in 2024 - Nature Reviews Earth & Environment
Global full-depth ocean heat content (OHC) gain since 1960 reached a record 452 ± 77 ZJ in 2024. OHC was 15 ± 9 ZJ higher than in 2023, primarily associated with warming in the Atlantic and Indian Oce...
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eLife @elife.bsky.social · 10/04/2025
Experiments in bacteria test the 50-year-old Ohno’s hypothesis that having duplicates of a gene (true for about 50% of them) allows evolution to accelerate. #EvoBio #Evolution
elifesciences.org
The value of gene duplication
Experiments in bacteria test a 50-year-old hypothesis on how duplicate genes help living things evolve.
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Adam Phillippy @aphillippy.bsky.social · 09/04/2025
A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...
A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.
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Zamin Iqbal @zaminiqbal.bsky.social · 09/04/2025
So glad this is finally out. The method has been instrumental in allowing us to compress the AllTheBacteria data - ~2 million bacterial genomes shrink from 3Terabytes (gzipped) to 100Gb using phylogenetic compression. Great work by @brinda.eu
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Carolina Monzó @carolinamonzo.bsky.social · 28/03/2025
It's finally out!!!! Our review on long-reads transcriptomics was published in @natrevgenet.bsky.social!! You can have a look at the paper here rdcu.be/efugl! We hope you like it 😀
rdcu.be
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Jaime Martinez-Urtaza @jaimemurtaza.bsky.social · 28/03/2025
Anthropogenic activity and climate change exacerbate the spread of pathogenic bacteria in the environment | Science Advances www.science.org/doi/10.1126/...
science.org
Anthropogenic activity and climate change exacerbate the spread of pathogenic bacteria in the environment
Climate change and human activity will increase global richness and abundance of pathogenic bacteria, threatening public health.
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Reposted by Jaime Martinez-Urtaza
jenswalter15.bsky.social @jenswalter15.bsky.social · 25/03/2025
It is hard to determine habitat adaptations in host-associated bacteria, e.g. because strains might be allochthonous or mislabeled. Here we present aurora, a gwas tool that identifies autochthonous strains and the genes associated with their habitats. doi.org/10.1186/s130...
doi.org
aurora: a machine learning gwas tool for analyzing microbial habitat adaptation - Genome Biology
A primary goal of microbial genome-wide association studies is identifying genomic variants associated with a particular habitat. Existing tools fail to identify known causal variants if the analyzed ...
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Reposted by Jaime Martinez-Urtaza
Nature Reviews Microbiology @natrevmicro.nature.com · 25/03/2025
New online! Ecology, global diversity and evolutionary mechanisms in the Mycobacterium tuberculosis complex
nature.com
Ecology, global diversity and evolutionary mechanisms in the Mycobacterium tuberculosis complex
Nature Reviews Microbiology, Published online: 25 March 2025; doi:10.1038/s41579-025-01159-wIn this Review, Gagneux and colleagues discuss ecological and evolutionary concepts related to the biology and epidemiology of the Mycobacterium tuberculosis complex, including new phylogenetic lineages, host tropism among the various animal-adapted lineages, the evolutionary dynamics of antimicrobial resistance and transmission, as well as within-host diversity and structural genomic variation.
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Nature Communications @natcomms.nature.com · 17/03/2025
In the era of #ClimateChange human societies face growing exposure to disasters and complex #climate risks. In this perspective, @reichstein-bgc.bsky.social, @vitusbenson.bsky.social, et al., explore the potential of integrated #ArtificialIntelligence in developing multi-hazard #EarlyWarningSystems
nature.com
Early warning of complex climate risk with integrated artificial intelligence - Nature Communications
In the era of climate change, human societies face growing exposure to disasters and complex climate risks. This perspective explores the transformative potential of integrated Artificial Intelligence...
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Reposted by Jaime Martinez-Urtaza
Antonio Vecoli (@tonyveco on X) @tonyveco.bsky.social · 11/03/2025
🔴⚠️🧊🌡️Dramatic conditions for the Arctic Circle as from the latest ERA5 data. It was hotter than the ref.per. 1991-2020 almost everywhere in the #Arctic with a max anomaly of +10.6°C for Feb.2025. Daily anomaly reached even +20°C in some areas, with seaice at their smallest extent ever for February
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Jaime Martinez-Urtaza @jaimemurtaza.bsky.social · 08/03/2025
Europe's climate leadership in an ‘America first’ era - @lancetrh-europe.bsky.social Spain's 2024 simultaneous battle with deadly floods and severe droughts is a stark reminder that climate change already endangers lives in Europe. www.thelancet.com/journals/lan...
thelancet.com
Europe's climate leadership in an ‘America first’ era
Withdrawing from the World Health Organization and the Paris Agreement (again), cutting climate, health and development funding, purging climate mentions from websites, muzzling the Centers for Diseas...
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Guillaume Méric @gmeric.bsky.social · 06/03/2025
Lab mice (domesticated for >100y) have kept gut bacterial strains that codiversified w/ rodents for >25My. Here, authors show genetic drift occured in the lab, leading to loss of microb diversity+more deleterious mutations, impacting microbial fitness in lab vs wt mice www.nature.com/articles/s41...
nature.com
Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice - Nature Communications
Here the authors show that lab mice have retained ancient gut bacterial symbionts that diversified in parallel with rodent species, but the genomes of these gut bugs have accumulated mutational burden...
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Dr. Miles Roberts @milesroberts.bsky.social · 05/03/2025
Our review on k-mers + pop gen is now published! doi.org/10.1093/molb...
doi.org
k-mer-based approaches to bridging pangenomics and population genetics
Abstract. Many commonly studied species now have more than one chromosome-scale genome assembly, revealing a large amount of genetic diversity previously m
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Jed Fuhrman @jedfuhrman.bsky.social · 27/02/2025
Just out - The first global ocean 3-Domain microbial survey where all organisms can be directly compared quantitatively. Unfractionated and amplified from just 2 primers (vetted with mock communities and metagenomics), so all with the same denominator. www.biorxiv.org/content/10.1...
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danielfalush.bsky.social @danielfalush.bsky.social · 28/02/2025
Delighted to present our Macrogenetics atlas of prokaryotes. www.biorxiv.org/content/10.1... This is a herculean effort from Chao Yang, which has a previous existence as a preprint first posted in 2018 "why panmictic bacteria are rare?" www.biorxiv.org/content/10.1...
biorxiv.org
Macrogenetic atlas of prokaryotes
Macrogenetics investigates the patterns and predictors of intraspecific genetic variation across diverse taxa, offering a framework to address longstanding evolutionary hypotheses. Here, we present a ...
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Guillaume Méric @gmeric.bsky.social · 27/02/2025
Very interesting new preprint from the Falush lab in Shanghai, describing an effort to parameterize a large number of microbial and population (phylo)genetic traits for >15k species, then examining their interactions. Loads to dig up & possibly quite impactful! 🔗 www.biorxiv.org/content/10.1...
biorxiv.org
Macrogenetic atlas of prokaryotes
Macrogenetics investigates the patterns and predictors of intraspecific genetic variation across diverse taxa, offering a framework to address longstanding evolutionary hypotheses. Here, we present a ...
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