Author summary Bacterial gene positioning affects gene expression because genes near the origin of chromosomal replication are replicated earlier than those near the terminus and thus have higher gene...

Saturn’s icy moon Enceladus features chemical signatures consistent with an alkaline soda ocean with H2 production via hydrothermal water-rock reactions. Chemolithoautotrophic methanogenesis is thermo...

NASA's Pathfinder lander and Sojourner rover made history on Mars, setting the stage for bigger missions to come.

NASA Chief Scientist for Small Body Exploration at Johnson Space Center, Paul Abell, takes us inside Hayabusa2's flyby of asteroid Torifune and the…

Some educators are pushing back in class and in court against the display of the religious code in public schools

Textural, mineralogical, and chemical analyses of the Jezero crater Margin unit from Perseverance’s SuperCam identify multiple episodes of aqueous alteration driven by early carbon-rich fluids, paleol...

Why information is the unifying principle that allows us to understand the evolution of complexity in nature

Alternative response programs, where mental health clinicians respond to 911 calls instead of police, have proliferated since George Floyd's murder. What does it take to do this work well?

A 3-D thermal model identifies a ~ 4.33 Ga temporal “sweet spot” for life’s origin, when decreased bombardment enabled mild hydrothermal niches to support RNA World chemistry and stable biomolecu...

The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.

The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.

Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.

President Donald Trump on Sunday provided a new reason to justify his proposal to build a 250-foot triumphal arch directly across Arlington National Cemetery, saying the structure would double as a “t...

Exclusive: key White House loyalist orchestrating multi-agency effort condemned by critics as cruel and racist

Explore open science trends for your organization and compare against data for peer organizations, research field and country using the PLOS Open Science Indicators dashboard.

Learn about International Observe the Moon Night and plan ahead. Here are our program goals, future event dates, and more!

Prototypes of specially engineered transmission electron microscopes deliver images with greatly improved contrast to cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) projects...

In this Perspective, Levin and Wang give a brief history of bacterial growth rate and discuss how it is connected to nutrient availability and macromolecule synthesis, with a focus on (p)ppGpp as a ce...

The Department of Biology at Stanford University seeks applicants for a tenure-track Assistant Professor in Evolutionary Biology. A successful candidate will conduct research that asks fundamental que...

This was a seriously iconic lineup.

While parked at a sand ridge nicknamed “Chocolatal,” NASA’s Curiosity Mars rover used its black-and-white navigation cameras to capture panoramas at two times

ALT: Man Lying on a Pile of Money

A new global democracy report finds the U.S. at its lowest level of democratic performance in the 50 years it has been measured.