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Alessio Mengoni

@alessiome.bsky.social
38 followers 43 following 11 posts

Doing (some) science and teaching genetics @ Univ. of Florence, Italy.

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Alessio Mengoni @alessiome.bsky.social · 23/08/2026
Can domestication reshape plant–microbe dialogue? 🌾🦠 Dual #transcriptomics + #hormonomics reveal distinct G×G responses of beneficial endophytes to wild vs cultivated rice, raising questions about phytohormone signaling in colonization. link.springer.com/article/10.1...
link.springer.com
Comparative transcriptomic analysis reveals distinct responses of beneficial bacterial endophytes to wild and cultivated rice root exudates - Plant Cell Reports
Key message Root exudates from Oryza rufi pogon elicit stronger transcriptional responses in benefi cial bacterial endophytes and, together with bacterial inoculation, reveal distinct plant responses ...
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Carmen S. Cañizares @carmen-agro.bsky.social · 19/08/2026
Thanks @rachelwheatley.bsky.social & @friendlymicrobe.bsky.social for the invitation! We explore the fascinating social interactions of plant-associated bacteria & discuss how they can help design smarter microbial consortia! We enjoyed putting this review together & hope you enjoy reading it too!
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Marco Galardini @mgalactus.bsky.social · 12/08/2026
It took us two (2!) years to get our manuscript on resistance determinants to asobiotics published, and of course that had to happen during my summer vacation 🏝️🇪🇺 Thanks to @mulkern.bsky.social , @vuthuhien176.bsky.social and the other co-authors! www.nature.com/articles/s41...
nature.com
A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide - Nature Communications
In this study, authors investigate the evolution of bacterial resistance to antisense peptide nucleic acid (PNA) antibiotics. They observe that this typically occurs mainly by reducing drug uptake via...
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César de la Fuente @delafuentelab.bsky.social · 20/07/2026
Biology has plenty of data—the challenge is making it usable. AllTheBacteria transforms 2.44 million public bacterial and archaeal genomes into an open, uniformly processed, searchable, AI-ready resource. www.biorxiv.org/content/10.1...
biorxiv.org
AllTheBacteria: a community resource empowers biology and discovers novel peptide antibiotics
Public microbial genomes encode an immense record of biological diversity, evolution and molecular function, but much of this information remains difficult to reuse because raw sequencing data are not...
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Vittoria Brambilla @vittoriab.bsky.social · 20/07/2026
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Triple florigenic signaling in rice promotes stem elongation via transcriptional de‐repression
Rice florigenic proteins Hd3a, RFT1, and FT-L1 coordinate reproductive transition with stem elongation through repression of PINE1 expression, independently of floral MADS box proteins, relieving rep...
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Alessio Mengoni @alessiome.bsky.social · 18/07/2026
Why are there still so many unknown function genes in microbial genomes? Are they as an "epistemological mirror", silent on classical microbiology (pure culture) test. Perspective paper in Heredity from the lab @francescavaccaro.bsky.social and Camilla Fagorzi nature.com/articles/s41437-026-00870-5
nature.com
The microbial unknome, a repertoire for microbial chatting? - Heredity
Heredity - The microbial unknome, a repertoire for microbial chatting?
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ICMB2026 @icmb2025.bsky.social · 01/04/2026
We are excited to announce ICMB 2026 keynote speakers!🎉 ICMB 2026 is bringing together three pioneers who are redefining how we understand life Prof. Dr. Eva Kondorosi, Prof. Dr. Nikolaus Rajewsky and Prof. Dr. Andrei Lupas. Take a look at our website: icmb2026.stiinta-cercetare.ro
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Vittoria Brambilla @vittoriab.bsky.social · 21/05/2026
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Vittoria Brambilla @vittoriab.bsky.social · 27/04/2026
I have some news! Fabio Fornara and I published a book! We are very happy of it!
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Peter DeWeirdt @pdeweirdt.bsky.social · 02/04/2026
Excited to see our work out in Science today! Using machine learning to identify prokaryotic immune systems www.science.org/doi/10.1126/...
science.org
DefensePredictor: A machine learning model to discover prokaryotic immune systems
Antiphage defense systems protect bacteria from viral infection and have inspired important biotechnologies such as CRISPR-Cas9 while also revealing the evolutionary roots of eukaryotic innate immunit...
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Chris Thorogood @christhorogood.bsky.social · 28/03/2026
We sequenced the genome of 'desert ginseng' (Cistanche deserticola) - a leafless parasitic plant that gave up photosynthesis - and found it lost huge chunks of its own genome…but started stealing genes from its host! Thanks to my collaborators Prof Huang + her talented team👏🏻 lnkd.in/evF5iU9G
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Giorgia Lodi @giorgialodi.bsky.social · 23/03/2026
Office.eu è un’alternativa completamente europea alle popolari suite come Microsoft Office e Google Workspace ed è stata lanciata ufficialmente
office.eu
Office EU - Europe's Open-Source Productivity Suite
Welcome to Office EU, the open-source productivity platform for all who value a free, transparent and sovereign working environment.
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Vicky Lioy @vslioy.bsky.social · 20/03/2026
The I2BC is now accepting applications for new group leader positions. Explore our research at the Institute in our Journal: www.scoop.it/u/institut-d... Deadline: April 22, 2026 @i2bcparissaclay.bsky.social
scoop.it
I2BC Paris-Saclay | Scoop.it
Scoop.it enables professionals and businesses to research and publish content through its content curation tool.
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Carmen S. Cañizares @carmen-agro.bsky.social · 20/03/2026
Similar microbes, different outcomes. Why do some rhizobial bacteroids fix nitrogen in legumes better than others? Check out the online version of our latest work by @poolelaboxford.bsky.social, an historical lab project showing how this comes down to differentiation 😉 ➡️ doi.org/10.1093/plph...
doi.org
Developmental fates and N2-fixing efficiency of terminally-differentiated versus undifferentiated bacteroids from legume nodules
The higher symbiotic efficiency of pea bacteroids arises from their greater packing density and proteomic bias toward nitrogenase and dicarboxylate metabol
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Bioinformatics Advances @bioinfoadv.bsky.social · 13/03/2026
memod-s is a Snakemake-based workflow that streamlines analysis of prokaryotic DNA methylation from Nanopore sequencing data. The pipeline integrates basecalling, quality control, genome assembly, annotation, & methylation profiling to generate genome-wide methylation statistics & visualisations.
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Bioinformatics Advances @bioinfoadv.bsky.social · 13/03/2026
🧪 The memod-s workflow is available at
github.com
GitHub - AlessiaMarotta/memod-s: A standardised workflow to explore and analyse prokaryotic methylation patterns for Nanopore sequencing data
A standardised workflow to explore and analyse prokaryotic methylation patterns for Nanopore sequencing data - AlessiaMarotta/memod-s
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Bioinformatics Advances @bioinfoadv.bsky.social · 13/03/2026
🧬 New in Bioinformatics Advances: "Memod-s: A standardised workflow to explore and analyse prokaryotic methylation patterns for Nanopore sequencing data"  Explore the study: doi.org/10.1093/bioadv/vbag072  Authors include: @alessiome.bsky.social, @jaimemurtaza.bsky.social
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Alessio Mengoni @alessiome.bsky.social · 03/10/2025
Do you like blueberries? I do, but what's going on in declining wild populations of blueberry of Italian Apennines? Of course from the microbiota perspective! If you are curious see here: journals.sagepub.com/doi/10.1177/... Another nice paper from @francescavaccaro.bsky.social and Camilla Fagorzi
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Alessio Mengoni @alessiome.bsky.social · 23/09/2025
So glad and happy to be at the Biotechnology Summer School "The Green Side of One Health: From Basics to Industrial Applications” in wonderful #Kaszuby, Poland bss.ug.edu.pl One week of science, fun and inspiration from young scientists. With @francescavaccaro.bsky.social and Camilla Fagorzi
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Alessio Mengoni @alessiome.bsky.social · 08/07/2025
Glad to participate to the 🌞 school in #Padua on "Why do we study plants". Tnx to @lorellanavazio.bsky.social and Barbara Baldan for inviting me. @unipd.bsky.social Fantastic lectures by @christhorogood.bsky.social @oxforduni.bsky.social on the #Rafflesia flowers
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alymischa @alymischa.bsky.social · 01/07/2025
Happy to repost on my new Bluesky profile 🌱 In our study published on May 8,we successfully adapted the #PhenotypeMicroarray approach to plant #protoplasts, opening new possibilities for high-throughput metabolic phenotyping at cell level! 🔗 📖 rdcu.be/ek5iH @springernature.com @alessiome.bsky.social
rdcu.be
Phenotype microarray-based assessment of metabolic variability in plant protoplasts
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Alessio Mengoni @alessiome.bsky.social · 01/07/2025
New paper from the lab. Take-away message: redundancy of functions in consortia led to more effective lab-to-the-field translation. Great collaboration with IBBR-CNR and Univ. Palermo. With contribution by L. Cangioli, @francescavaccaro.bsky.social , C. Fagorzi www.sciencedirect.com/science/arti...
sciencedirect.com
Soil bacteria and symbiotic rhizobia synergistically promote nitrogen fixation and biomass production of alfalfa (Medicago sativa L.) plants even under water shortage conditions without altering the n...
In modern and sustainable agriculture, the exploitation of biological nitrogen fixation (BNF) is an alternative to synthetic nitrogen fertilizers whic…
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Alessio Mengoni @alessiome.bsky.social · 11/04/2025
New from the lab 📰 Toward deciphering the molecular dialogue in the rhizomicrobiota: Transcriptomic profiling of Trichoderma in rhizobia interaction. Work led by @francescavaccaro.bsky.social just few weeks before defending her PhD and Camilla Fagorzi! www.sciencedirect.com/science/arti...
sciencedirect.com
Toward deciphering the molecular dialogue in the rhizomicrobiota: Transcriptomic profiling of Trichoderma in rhizobia interaction
Microbial interactions are of key importance for the emergent properties of microbiota and ecosystems, playing a pivotal role in plant health, growth,…
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Matthias C. Rillig @mrillig.bsky.social · 05/04/2025
"We infer that the earliest aerobic bacteria emerged in the Archaean, predating the GOE by 900 million years." Oxygen tolerance may have been a prerequisite for, rather than a consequence of, the evolution of oxygenic photosynthesis www.science.org/doi/10.1126/...
science.org
A geological timescale for bacterial evolution and oxygen adaptation
Microbial life has dominated Earth’s history but left a sparse fossil record, greatly hindering our understanding of evolution in deep time. However, bacterial metabolism has left signatures in the ge...
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Vittoria Brambilla @vittoriab.bsky.social · 31/03/2025
academic.oup.com/plphys/advan... Flowering time and cell wall
academic.oup.com
Mutations in HEADING DATE 1 affect transcription and cell wall composition in rice
A zinc finger transcription factor that is central to photoperiodic flowering also plays a role in determining cell wall composition and abiotic stress res
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Carmen S. Cañizares @carmen-agro.bsky.social · 25/03/2025
We also offer travel grants for Early Career Researchers thanks to the support of @amiposts.bsky.social & @jxbotany.bsky.social. Applications open until 15/04. Check all the info in our website and stay tuned for all the upcoming news and a very exciting programme! ➡️ web.cvent.com/event/aa2ad9...
web.cvent.com
16th European Nitrogen Fixation Conference
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Carmen S. Cañizares @carmen-agro.bsky.social · 25/03/2025
We are looking forward to hosting the next European Nitrogen Fixation Conference in Oxford the 26th-29th August. We have already announced our invited speakers and are now excited to receive your abstracts! Keep an eye on our key dates: 🗓️ 30/04 Early bird registration 📝 01/05 Abstract submission
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Ákos T Kovács @evolvedbiofilm.bsky.social · 19/03/2025
Sinorhizobium meliloti FcrX coordinates cell cycle and division during free-living growth and symbiosis by a ClpXP-dependent mechanism -in PNAS from Emanuele Biondi www.pnas.org/doi/full/10....
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Vicky Lioy @vslioy.bsky.social · 15/03/2025
We are very happy to share our latest preprint! 📣 H-NS is a xenogeneic silencer that prevents the costly expression of horizontally acquired genes. In Salmonella, H-NS silences several Pathogenicity Islands (SPIs), including SPI-1, which is essential for host invasion. 🧵⬇️
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Anna Meldolesi @annameldolesi.bsky.social · 14/03/2025
Probabilmente no, perché hanno agito di notte col passamontagna. E perché sia i media che la politica hanno speso ben poche parole quando questi episodi sono accaduti, nel giugno 2024 ai danni dell’Università di Milano e nel febbraio del 2025 ai danni dell’ateneo di Verona 2/3
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Asaf Levy @asaflevylab.bsky.social · 01/03/2025
A controlled study on the sociology of science: We published last year two papers on bacterial toxins in the same journal ("Molecular Systems Biology"), edited by the same editor, both describe discovery of toxins associated with secretion systems that were predicted computationally and validated
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Michael Brockhurst @brockhurstlab.bsky.social · 24/02/2025
📣Just 1 week left to apply for 2x 5-year researcher posts in experimental evolution #mevosky #microsky in @mermanchester.bsky.social @official-uom.bsky.social + 3-year research tech post www.jobs.manchester.ac.uk/Job/JobDetai... ERC project: how MGEs and defence systems control genome evoluton
jobs.manchester.ac.uk
Research Technician in Microbiology:Manchester
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Anna Meldolesi @annameldolesi.bsky.social · 16/02/2025
Eco-vandals target gene-edited Chardonnay in Italy. Antiscience stupidity strikes again: two experimental fields have been launched in the country, and both have been attacked #CRISPR #agriculture #vandalism (link below)
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Anna Meldolesi @annameldolesi.bsky.social · 16/02/2025
Due campi sperimentali avviati, due campi vandalizzati da ignoti. C'è la volontà politica di contrastare questi reati? #CRISPR #agricoltura #TEA #ecovandali crispr.blog/2025/02/16/v...
crispr.blog
Viti TEA vandalizzate. E adesso?
Nella notte tra il 12 e il 13 febbraio ignoti vandali hanno fatto irruzione nel campo sperimentale dell’Università di Verona danneggiando le viti Chardonnay editate per combattere un’in…
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Marco Galardini @mgalactus.bsky.social · 12/02/2025
Our paper describing the microGWAS pipeline was published yesterday in Microbial Genomics. Lots of fixes and additions to the code/documentation since the preprint, including a hard to reproduce bug that only showed up in a specific HPC 🥵 www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
microGWAS: a computational pipeline to perform large-scale bacterial genome-wide association studies
Identifying genetic variants associated with bacterial phenotypes, such as virulence, host preference and antimicrobial resistance, has great potential for a better understanding of the mechanisms inv...
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Vittoria Brambilla @vittoriab.bsky.social · 22/01/2025
We found this gene that is important for correct carpel development in rice. It encodes for a plant mobile protein. link.springer.com/article/10.1...
link.springer.com
OsMAINTENANCE OF MERISTEM LIKE 1 controls style number at high temperatures in rice - Plant Molecular Biology
OsMAIL1 encodes for a rice protein of the Plant Mobile Domain (PMD) family and is strongly upregulated during floral induction in response to the presence of the florigens Heading date 3a (Hd3a) and R...
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Giulio Betti @giuliofirenze.bsky.social · 09/01/2025
Il mio intervento a Effetto Giorno sugli incendi in California. Minuto 35:14 www.radio24.ilsole24ore.com/programmi/ef...
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Anna Meldolesi @annameldolesi.bsky.social · 10/01/2025
Atomic spaghetti, an Italian story #mutationbreeding mycrispr.blog/2025/01/09/a...
mycrispr.blog
Atomic spaghetti and mutagenesis B.C. (before CRISPR)
Before the advent of genome editing and GMOs, mutagenesis was achieved through radiation. This technique was also used to modify varieties of durum wheat, which, through crossbreeding, contributed …
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Alessio Mengoni @alessiome.bsky.social · 09/01/2025
"The Complex Epigenetic Panorama in the Multipartite Genome of the Nitrogen-Fixing Bacterium Sinorhizobium meliloti" After many rounds of revision and re-analysis I'm very happy to share the paper on genome-wide methylation analysis of S. meliloti. academic.oup.com/gbe/article/...
academic.oup.com
The Complex Epigenetic Panorama in the Multipartite Genome of the Nitrogen-Fixing Bacterium Sinorhizobium meliloti
Abstract. In prokaryotes, DNA methylation plays roles in DNA repair, gene expression, cell cycle progression, and immune recognition of foreign DNA. Genome
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Raphael Viscarra Rossel @ravr19.bsky.social · 26/12/2024
Good piece by @natureportfolio.bsky.social. The erosion of thinking time—driven by admin, bureaucracy, industry agendas, and unrealistic output targets—stifles curiosity-led science. These pressures undermine innovation and the intellectual freedom vital for real progress. 🧪🌱🌍 #ScienceIsNotBusiness
Scientists need more time to think
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Toby Kiers @tobykiers.bsky.social · 11/12/2024
The rhizosphere has been called “one of the most complex ecosystems on earth” But how do host plants control benefits derived from their microbial partners? Read our paper in Nature Microbiology on how legumes mediate conflict & cooperation with N2-fixing symbionts. Here: tinyurl.com/4y4tjx6k
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Giulio Betti @giuliofirenze.bsky.social · 10/12/2024
Per chi volesse il 12 dicembre alle ore 21.00, presso la biblioteca delle Oblate, a Firenze, parlerò di Meteorologia nell'Arte. Organizzatore: Caffè Scienza. Entrata: rigorosamente gratuita
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Julian Trouillon @juliantrouillon.bsky.social · 06/12/2024
I have an open Postdoc position in Molecular Systems Biology at ETH Zürich! The project is about the conservation of transcription factors functions between strains of Pseudomonas aeruginosa 🧬🦠 More details and application at: jobs.ethz.ch/job/view/JOP... Please share!
jobs.ethz.ch
Postdoctoral Position in Molecular Systems Biology
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Michael Brockhurst @brockhurstlab.bsky.social · 07/12/2024
Keeping your symbiosis genes on a plasmid is a smart move if you have multiple potential hosts. Here a gut bacterial symbiont, but same is true for N-fixing Rhizobia. www.science.org/doi/10.1126/...
science.org
A conserved bacterial genetic basis for commensal-host specificity
Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...
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Vittoria Brambilla @vittoriab.bsky.social · 03/12/2024
With Roberto Defez we tried to describe what's going on in Italy with GMOs and NGTs. And how we see it in the European scenario. Out today in EMBO Reports www.embopress.org/doi/full/10....
embopress.org
The history of GM crops in Italy: After two decades of a de facto ban, the engagement of farmers and scientists has prompted the Italian government to allow field-testing of NGT/TEA plants again: EMBO reports: Vol 0, No 0
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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Anna Meldolesi @annameldolesi.bsky.social · 03/12/2024
Se fosse una serie Netflix potremmo dire che il 2024 delle biotecnologie agrarie in Italia si chiude con un ottimo finale di stagione e un po' di suspense. Il nuovo regolamento UE dividerà finalmente i destini di OGM e NGT/TEA? Dopo l'apertura alla sperimentazione arriverà la commercializzazione?
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Fiona J Whelan @whelanfj.bsky.social · 03/12/2024
🚨 PhD opportunity 🚨 The Whelan lab, along w @brockhurstlab.bsky.social, are looking for a PhD student w bioinformatic experience/interest to investigate the evolution of transmissibility in bacterial pathogens, with a focus on P. aeruginosa. More info & link to apply below. Please spread the word!
findaphd.com
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Vittoria Brambilla @vittoriab.bsky.social · 30/11/2024
link.springer.com/article/10.1...
link.springer.com
Integrating single nuclei and bulk RNA sequencing in rice shoot apical meristems uncovers candidate early floral transition gene networks - Plant Reproduction
Key message We describe transcriptional dynamics at the rice shoot apex by integrating time resolved single nuclei RNA-seq with bulk RNA-seq data. Abstract In rice, short days trigger floral transitio...
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Darren Obbard @darrenobbard.bsky.social · 27/11/2024
#PhD Advert: Please share! Are you looking for a PhD studentship in comparative- or population-genomics, using 300+ species of #Drosophila and 1000+ genomes of #melanogaster? #Entomology #Genomics #PopGen #Phylogenetics
Diverse species of Drosophilidae
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Jon Lim, FRCP PhD @drjonlim.bsky.social · 23/11/2024
🎨 In case anyone need… The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏! Check it out 👇 bioart.niaid.nih.gov
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