From 2003 to 2018, 13 million veterans had PFAS chemicals in their blood streams at levels higher than a threshold set by the National Academies.

Objective To directly test the generalisability of cardiovascular disease (CVD) risk predictor effects across populations in a high income versus non-high income country, derive comparable risk equati...

What happens after a biopsy is taken? When a biopsy is taken, we might think about what the results may be, or try not to,

The Cambridge academic has rightly now resigned. But that won’t end the targeting of senior black figures or the lazy way institutions promote faux equality, says Guardian columnist Jason Okundaye

Former residents of Cassiar say they weren’t warned about the risks. Now, they struggle to find support.

Podcast Episode · Real Feels - Modern Masculinity with Brad Gage · 10/28/2025 · 36m

Memory CD8+ T cells can undergo TCR-dependent or -independent activation. Here, Lee et al. show that IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions. Furthermore, they validate a bystander activation gene set induced by IL-15 and decreased upon TCR stimulation.

In this Review, Li and Underhill discuss recent advances in understanding the process of phagocytosis. The authors highlight how phagocytosis is integral for innate immune sensing and explain how the ...

Systemic metabolic homeostasis maintains circulating nutrient concentrations within physiological ranges. Insulin is central to this process, lowering circulating levels of glucose, free fatty acids, ...

In a landmark public health achievement, WHO has validated the Maldives for eliminating mother-to-child transmission (EMTCT) of hepatitis B, while maintaining its earlier validation (in 2019) for EMTCT of HIV and syphilis. This makes the Maldives the first country in the world to achieve ‘triple elimination’.

Outer mitochondrial membrane fusion is mediated by the mitofusin paralogs Mfn1 and Mfn2. Nucleotide-driven self-assembly and conformational changes are required for regulated membrane fusion activity,...

Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...

The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.

The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

A term favoured by US progressives can help us understand Britain’s drift to the right

Inflammation is an essential response to infection and injury, but unregulated inflammation is damaging and must be limited by negative feedback signalling. Inflammasome signalling drives local inflam...

Cardiff University confirmed it cannot rule out compulsory redundancies as it also apologised to students for problems with a new timetabling system as the academic year begins

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

It's a longstanding tradition to blame all manner of social ills on women, without any basis in fact.

Nature Methods - Clonalscope is a method for cancer subclone detection leveraging copy number profiles estimated using spatial and single-cell sequencing data.

The Galaxy single-cell and spatial omics community (SPOC) brings together over 175 tools, 120+ training resources, and a global user community in a unified FAIR platform. By integrating leading suites...

Nature Reviews Genetics, Published online: 30 September 2025; doi:10.1038/s41576-025-00892-5Spatial omics has empowered the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of disease heterogeneity within and across organs. The authors review spatially resolved molecular changes across diseases and discuss the potential of spatial multi-omics for clinical applications, including the recent impact of artificial intelligence.

A US Department of Veterans Affairs dataset compiling veteran health-care use in 2021 was quietly amended on March 5, 2025. A column titled gender was renamed sex, and the words were also switched in ...

Organelles spit out DNA contaminated with damaging components, leading to the activation of inflammatory enzymes, mouse experiments show.

Nature Reviews Endocrinology, Published online: 26 September 2025; doi:10.1038/s41574-025-01180-2Oestrogen is a key regulator in many metabolic processes, particularly in adipose tissue. This Review discusses the role of oestrogen in adipose tissue metabolism and its wider implications for systemic metabolic health.