Reposted by @dayyapparaja.bsky.social
Neha Ahuja studies how pancreatic cell types develop and simultaneously organise and shape into a complex organ, revealing a role for Merlin - a protein that links the cell membrane to intracellular scaffold proteins - in luminogenesis and exocrine acinar cell differentiation. #2026SDB
Preprint⤵️
biorxiv.org
Transient architecture of the embryonic pancreas determines endocrine mass
During organogenesis, epithelial tissues undergo extensive three-dimensional (3D) remodeling while simultaneously generating specialized cell types. Whether these transient architectural states active...