The Department of Biological Sciences at Columbia University invites applications for a tenure-track, Assistant Professor position. The successful ...

Summary: ZTF-30 represses BMP signaling during both larval development and dauer morphogenesis, driving the essential structural and cuticle remodeling required for C. elegans diapause.

The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

Physiological traits are modulated in response to diet. Here the authors show that RICTOR restrains host responses to vitamin B12 in C. elegans by modulating organellar quality control and regulating ...

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Abstract. All organisms must quickly acclimate to short-term environmental temperature changes to maintain optimal physiology. Temperature excursions far f

Summary: The similarity of the regulatory architecture of neurons and paraneurons revealed using cell identity markers to characterize the neuronal features of Caenorhabditis elegans uv1 paraneurons i...

Males and females are known to have dramatically different health and lifespan trajectories, but the underlying basis for these differences is yet to be fully elucidated. In the Caenorhabditis elegan

Biological age represents a quantifiable measure of physiological health that can be assessed using molecular biomarkers and potentially modulated through interventions. This review examines nutrition...

The nuclear hormone receptor NHR-49 regulates nutrition sensing and fatty acid metabolism in Caenorhabditis elegans. Here the authors show that NHR-49 activity in somatic cells regulates oocyte activa...

The consequence of enhanced energy metabolism for health and life span of organisms is a fundamental yet controversially discussed issue of life and aging among others because of the fact that increas...

Lucrative funding schemes seek to attract India’s scientists from world leading research facilities. But experts warn they are not a fix for structural issues.

Visualizing ionic dynamics in vivo reveals how rhythmic surges in intracellular proton levels regulate sleep.

The non-cell-autonomous functions of transcription factors in neuronal development remain poorly understood. Here, the authors show that UNC-3, the C. elegans homolog of the neurodevelopmental disorde...

npj Aging - Gut bacterial vesicles from the E. coliΔaroD mutant extend C. elegans lifespan

The 2026 cycle of the C. elegans Community Mentor Match is open to graduate students, postdocs, and faculty at any career stage. ⏱️ This form takes only 2–5 minutes to complete depending on your choic...

Touch is essential for survival, guiding interactions with the environment and forming the basis of social and emotional connection. While touch perce…

The authors use a Caenorhabditis elegans model of Verheij syndrome, caused by mutations in the splicing factor PUF60, and show that Vitamin B12 can rescue the phenotype.