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Stem Cell Reports

@stemcellreports.bsky.social
251 followers 67 following 283 posts

For scientists. By scientists. The official journal of the @isscr.org | Editor-in-Chief: Janet Rossant, CC, PhD

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Stem Cell Reports @stemcellreports.bsky.social · 29/09/2026
Stem Cell Reports Early Career Editor Luca Peruzzotti-Jametti is attending the Brayn Conference 2026 in Catania, Italy on 30 September - 2 October. Connect with him there to discuss whether your research is a fit for publishing in Stem Cell Reports! ow.ly/vVbb50ZQhCu
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Stem Cell Reports @stemcellreports.bsky.social · 21/09/2026
Help commemorate 20 years of iPSC discovery by contributing to a special issue of Stem Cell Reports. The journal is seeking original research and perspectives that reflect the impact and future of iPSC science. Submissions are due 1 December 2026. Learn more 👉 bit.ly/4wGN3hd
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Stem Cell Reports @stemcellreports.bsky.social · 02/07/2026
Researchers from the National University of Singapore recently discussed how they identified a new developmental mechanism that contributes to the absence of the nose using stem cell models. Listen to the latest episode of The Stem Cell Report podcast to learn more: ow.ly/X7gg50ZfXIw
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Stem Cell Reports @stemcellreports.bsky.social · 24/06/2026
Listen to the latest episode of The Stem Cell Report podcast to hear how researchers from the National University of Singapore are addressing human craniofacial development using stem cell models 👉 ow.ly/5FQ950ZfXzY
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Stem Cell Reports @stemcellreports.bsky.social · 04/06/2026
👏 Thank you, Martin Pera, for your transformative leadership of Stem Cell Reports. From launching The Stem Cell Report podcast to creating the Early Career Editorial Board & advancing research rigor, Martin helped shape the journal & elevate voices across the community. ow.ly/Ng8l50Z7G4O
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The ISSCR Celebrates Martin Pera for Transformative Leadership and Lasting Contributions to Stem Cell Reports as he Steps Down from the Journal’s Editorial Team — International Society for Stem Cell Research
The International Society for Stem Cell Research (ISSCR) and Stem Cell Reports are celebrating the remarkable contributions of Martin Pera as he concludes his long tenure with the journal following years of leadership that helped shape Stem Cell Reports into a leading voice in stem cell science
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Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 02/06/2026
Check out the paper in @stemcellreports.bsky.social www.cell.com/stem-cell-re... A collaborative effort between researchers at @fraunhoferitmp.bsky.social, @eu-openscreen.bsky.social, @mdc-berlin.bsky.social, and @hhu.de
cell.com
Human organoids: Fit for drug discovery?
Wittich et al. provide an overview of human PSC-derived organoid screening technologies and outline key considerations for integrating them into drug discovery pipelines. As new approach methodologies...
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Reposted by Stem Cell Reports
Alessandro Bertero @berterolab.bsky.social · 04/06/2026
I’m delighted to serve as an Early Career Editor for @stemcellreports.bsky.social, the society journal of @isscr.org. Stem Cell Reports welcomes rigorous work across the stem cell field, from basic mechanisms to emerging applications. Consider us for your next submission! invt.io/1bxb03y6b81
invt.io
Check out ISSCR's society journal, Stem Cell Reports!
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Stem Cell Reports @stemcellreports.bsky.social · 04/06/2026
🎉 Welcome to the newest Early Career Editors of Stem Cell Reports! Their global perspectives will help shape the future of stem cell science and publishing. 🌍Read more: ow.ly/Sji850Z7FmI Alessandro Bertero, Shifeng Xue,
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Stem Cell Reports @stemcellreports.bsky.social · 01/06/2026
Guests on the latest episode of The Stem Cell Report shared reports from Health Canada–regulated Phase I and Phase II trials evaluating freshly cultured umbilical cord–derived MSCs in patients with COVID-19-related ARDS. ow.ly/Cnr750Z2u4n
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Reposted by Stem Cell Reports
Dosh Whye @sciwhye23.bsky.social · 27/05/2026
From basic discovery to clinical translation, @ISSCR_org's open-access society journal showcases research shaping the field. @stemcellreports.bsky.social is the Official Meeting Journal of #ISSCR2026. Learn more about the journal and meet the editorial team this July! invt.io/1bxbkyomhe6
invt.io
Stem Cell Reports, the ISSCR 2026 Official Meeting Journal.
Learn more.
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Stem Cell Reports @stemcellreports.bsky.social · 27/05/2026
In the latest episode of The Stem Cell Report, guest share how their work explores a therapeutic strategy to improve ARDS outcomes using MSCs, which will be important for optimizing and targeting future cellular therapies. Listen to the full episode 👉https://ow.ly/Iytp50Z2sa9
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Stem Cell Reports @stemcellreports.bsky.social · 20/05/2026
New podcast episode! Guests from The Ottawa Hospital report results from a Health Canada-regulated Phase I and Phase II trials evaluating freshly cultured umbilical cord-derived MSCs in patients with COVID-19-related ARDS. Listen now 👉https://ow.ly/F7e650Z2rZK
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Stem Cell Reports @stemcellreports.bsky.social · 20/05/2026
Stem Cell Reports is proud to be the official meeting journal of BaCell 3D, taking place 22-24 June, 2026 in Basel, Switzerland. www.isscr.org/unaffiliated-events/b…
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Stem Cell Reports @stemcellreports.bsky.social · 13/05/2026
Online now! Mitochondrial toxins cause widespread downregulation of pathways in X-linked dystonia-parkinsonism patient-derived neurons. ow.ly/4WPA50YXPf8
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Stem Cell Reports @stemcellreports.bsky.social · 12/05/2026
Are human organoids fit for drug discovery? New review explores screening strategies, ML-enabled readouts, and advantages over traditional models, while addressing major challenges like scalability, robustness, throughput, and standardization needed for pharma adoption. ow.ly/nBPJ50YXP6z
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Stem Cell Reports @stemcellreports.bsky.social · 01/05/2026
Online Now! NRG-1 restoration reactivates NPCs and fosters hippocampal repair by supporting neurogenesis, neuronal complexity, synaptogenesis, and remyelination that reverses memory loss in mice with progressive brain demyelination👉 bit.ly/4t9sB6K
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Stem Cell Reports @stemcellreports.bsky.social · 29/04/2026
Stem Cell Reports, ISSCR's open-access, peer-reviewed journal, has been named the Official Conference Journal of the BaCell3D Organoid Conference, taking place 22-24 June 2026 in Basel, Switzerland. Read more 👉 ow.ly/Bo7Q50YRJff
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Stem Cell Reports @stemcellreports.bsky.social · 27/04/2026
Online now in Stem Cell Reports! TOE1 is a β-catenin interacting protein and novel regulator of hematopoietic cell proliferation through PAK2 modulation ow.ly/297I50YP49O ISSCR | Cell Press The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 24/04/2026
Check out this new #organoid research in Stem Cell Reports: MECP2 mutations rewire human embryonic stem cell fate and bias cortical lineage commitment ow.ly/N37850YP3V3 ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 20/04/2026
New paper provides ultrastructural and 3-D features of ventricular-subventricular zone (V-SVZ) neuroblasts in postnatal microminipigs, establishing them as a tractable gyrencephalic model for postnatal neurogenesis. ow.ly/gRnc50YKv4L ISSCR | The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 17/04/2026
Online Now! An optimized protocol for efficient derivation of pancreatic islets from multiple human pluripotent stem cell lines that enables production of highly functional stem cell-islets suitable for type 1 diabetes cell therapy. ow.ly/RUML50YKuVP ISSCR | Cell Press
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Stem Cell Reports @stemcellreports.bsky.social · 17/04/2026
In this anniversary episode, Janet Rossant is joined by a few of our past guests who helped define the conversations of the past five years. Revisit where their work stood then, explore where it has gone since, & take a closer look at what lies ahead 👉https://ow.ly/WcRv50YJ0Uo
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Stem Cell Reports @stemcellreports.bsky.social · 16/04/2026
Check out this new intestinal #organoid research: Phenotypic screening identified that glycyrrhizin confers protection against tumor necrosis factor-induced cell death, which may be a novel therapeutic compound for Crohn’s disease. ow.ly/VZvQ50YKuMG
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Stem Cell Reports @stemcellreports.bsky.social · 13/04/2026
New #RareDisease research! Bosma arrhinia microphthalmia syndrome (BAMS) is marked by the absence of a nose and eye/reproductive anomalies, which may result from impaired differentiation to cranial placode cells and changes in cell adhesion. ow.ly/kRPX50YGFGl
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Stem Cell Reports @stemcellreports.bsky.social · 13/04/2026
Stem Cell Reports, ISSCR's open-access, peer-reviewed journal, has been named the Official Conference Journal of the BaCell3D Organoid Conference, taking place 22-24 June 2026 in Basel, Switzerland. Read more 👉 ow.ly/mesl50YInK1
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Stem Cell Reports @stemcellreports.bsky.social · 10/04/2026
Chemotherapy-induced thrombocytopenia (CIT) is a severe complication in elderly cancer patients. New research shows that dietary restriction mitigates CIT in aged mice via mitochondrial potentiation in hematopoietic stem cells and megakaryocyte progenitors. ow.ly/VpFm50YEMX5
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Stem Cell Reports @stemcellreports.bsky.social · 10/04/2026
A nuclear receptor screen identifies Rora as a dose-dependent regulator of cell fate. Transcription factor dosage—not just identity—drives reprogramming efficiency, pointing to nuclear receptor modulation as a lever for cell plasticity ow.ly/B4jU50YEN1g
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Stem Cell Reports @stemcellreports.bsky.social · 09/04/2026
A screen of 49 nuclear receptors identifies the ROR subfamily as OKS (OCT4/KLF4/SOX2) enhancers. Rora acts as a dose-dependent regulator of cell fate, tuning reprogramming efficiency. ow.ly/XPlQ50YEMWN Cell Press | The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 09/04/2026
Stem Cell Reports is pleased to announce the appointment of Hongmei Wang, Ph.D., as an Associate Editor. Dr. Wang is a professor of State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology (IOZ), Chinese Academy of Sciences (CAS). Read more 👉https://ow.ly/rfEu50YGw9E
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Stem Cell Reports @stemcellreports.bsky.social · 08/04/2026
New research from Duke University in Stem Cell Reports uses multimodal human podocyte injury models to discover kidney disease targets, highlighting the predictive power of human-relevant experimental models. ow.ly/5gsa50YEMWk Cell Press | The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 07/04/2026
Online Now! A semi-automated multi-electrode arrays (MEA) spike sorting method for high-throughput assessment of cultured neurons; enhances the resolution & utility of MEA in disease modeling and drug development using hPSC-derived neurons. ow.ly/lzkW50YEMVV
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Stem Cell Reports @stemcellreports.bsky.social · 06/04/2026
Stem Cell Reports is proud to be the official meeting journal for the 20th Annual Wisconsin Stem Cell Symposium! Learn more about the event 👉 stemcells.wisc.edu/7376-2
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Stem Cell Reports @stemcellreports.bsky.social · 03/04/2026
Thrombopoietin (THPO)-driven neonatal hematopoiesis establishes the hematopoietic stem cell and multipotent progenitor cell hierarchy. While its role is limited in adults, THPO is critical during early development for a structured hematopoietic system. ow.ly/sOca50YARe5
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Stem Cell Reports @stemcellreports.bsky.social · 02/04/2026
New! 3D Vessels-on-Chip using isogenic hiPSC-derived VSMCs reveal NOTCH3-driven alterations in brain small vessel disease, providing platform for mechanistic studies and therapeutic testing. ow.ly/XkVS50YALSQ Cell Press | The Gairdner Foundation | SickKids Foundation
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Stem Cell Reports @stemcellreports.bsky.social · 01/04/2026
Stem Cell Reports announces measures to strengthen scientific rigor with new publication standards today. Advancing transparency, reproducibility, and trust in stem cell science. www.isscr.org/isscr-news/s... @isscr.org @cellpress.bsky.social @sickkidsvs.bsky.social
isscr.org
Stem Cell Reports Strengthens Commitment to Scientific Rigor with New Publication Standards — International Society for Stem Cell Research
Requirements effective today advance transparency, reproducibility, and global research standards in stem cell science The International Society for Stem Cell Research (ISSCR) today announced that ...
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Stem Cell Reports @stemcellreports.bsky.social · 01/04/2026
The challenges of choosing your pluripotent stem cell line. A new letter explores whether to use a “ready-to-use” hPSC line or make a new one, and how that choice impacts suitability for the intended clinical indication and resulting cell types. ow.ly/5rCu50YALJY
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Stem Cell Reports @stemcellreports.bsky.social · 31/03/2026
New review in Stem Cell Reports from CiRA, Kyoto University discusses the developmental origins and functions of microglia, current differentiation approaches, and how these models help elucidate disease-relevant phenotypes and molecular mechanisms in neurodegeneration. ow.ly/q8qF50YALC3
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Stem Cell Reports @stemcellreports.bsky.social · 30/03/2026
Online now: Mechano-electrical stimulation enhances peripheral nerve regeneration by activating and directing neural crest stem cell differentiation, supporting a novel therapeutic approach to stem cell modulation for nerve repair. ow.ly/8Ayu50YALtR
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Stem Cell Reports @stemcellreports.bsky.social · 27/03/2026
Out Now in Stem Cell Reports! A practical framework for hiPSC model development with stem cell-specific guidance on reporting diversity and a four criteria tool (purpose, plausibility, readiness, and power) to determine when and how to incorporate diversity in research.  ow.ly/qkSE50YwSug
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Stem Cell Reports @stemcellreports.bsky.social · 26/03/2026
Diversity of cortical progenitors directs neuronal layer formation and regional glial patterning supporting a model in which fate potential and timing co-regulate the spatial and laminar organization of cortical cell types. ow.ly/gjc850YwSjP
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Stem Cell Reports @stemcellreports.bsky.social · 25/03/2026
New from CiRA in Stem Cell Reports! Deuterosomal cells are the responsible lineage for multiciliogenesis in human airway differentiation. An iPSC-based platform for investigating mechanisms underlying airway multiciliogenesis and modeling primary ciliary dyskinesia. ow.ly/8afr50YwSbK
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Stem Cell Reports @stemcellreports.bsky.social · 24/03/2026
Toward standardized iPSC testing: A multi-year international study highlights variability in flow cytometry (pluripotency) and qPCR (genomic integrity) assays, underscoring the urgent need for harmonized QC to support global adoption of iPSC-derived therapies. ow.ly/s1G850YwS6f
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Stem Cell Reports @stemcellreports.bsky.social · 23/03/2026
Propofol, a common anesthetic, shows region-specific effects in human forebrain organoids, enhancing growth, neuronal excitability, and action potential activity. A new model to study anesthetic impacts on early brain development. ow.ly/XGvE50YwRUK
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Stem Cell Reports @stemcellreports.bsky.social · 20/03/2026
New research from the UC Davis School of Medicine : A new humanized engineered heart tissue platform provides a more sensitive system for evaluating cardiotoxicity and is more stringent than conventional monolayer approaches. #xenobiotics #drugscreening ow.ly/Ljl850YwRJ8
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Stem Cell Reports @stemcellreports.bsky.social · 19/03/2026
New study presents results from the CIRCA-19 trials evaluating umbilical cord–derived mesenchymal stromal cells for severe COVID-19 acute respiratory distress syndrome. Cells were well tolerated and linked to improved clinical outcomes & recovery from lymphopenia. ow.ly/Mc1k50Yt8BR
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Stem Cell Reports @stemcellreports.bsky.social · 19/03/2026
Stem Cell Reports is proud to be the Official Meeting Journal of the 20th Annual Wisconsin Stem Cell Symposium, taking place in Fitchburg, Wisconsin, USA on 15 April 2026. Learn more: ow.ly/AaHY50Yw013
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Stem Cell Reports @stemcellreports.bsky.social · 18/03/2026
Listen to the latest episode of The Stem Cell Report podcast to explore how the guests developed new laboratory models to study Merkel cell development using mouse whisker tissue cultures, mouse skin organoids, and human skin organoids. ow.ly/fNnw50YrsVA
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Stem Cell Reports @stemcellreports.bsky.social · 17/03/2026
Online Now! Nuclear Lipin1 recruits HDAC2 to epigenetically repress SREBP1-dependent lipid synthesis and myelination in hypoxic preterm white matter injury, offering targets for white matter repair in preterm infants. ow.ly/7ry150Yt8tB Cell Press
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Stem Cell Reports @stemcellreports.bsky.social · 16/03/2026
New article highlights Korea’s new Advanced Regenerative Medicine Treatment (ARMT) category under its amended regenerative medicine law, focusing on patient access, review processes, safety monitoring, ethical safeguards, and lessons from Japan’s comparable framework. ow.ly/6kyf50Yt8ps
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Stem Cell Reports @stemcellreports.bsky.social · 13/03/2026
New research from RIKEN: Canonical & non-canonical WNT signaling pathways sequentially orchestrate early retinal morphogenesis and environmental factors within the host retina strongly drive the alignment and functional integration of graft photoreceptors. ow.ly/LChR50Yqg7p ISSCR
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