Reposted by Jeremy DayNobel Prize @nobelprize.org · 19hBREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.” 16977478
Reposted by Jeremy DayMatt Hill @cannabrain.bsky.social · 02/10/2026**Recruitment** We are looking to hire a psychiatrist/scientist (MD or MD/PhD) who focuses on neuromodulation, particularly rTMS in the Department of Psychiatry at the University of Calgary. Come join myself, @mayoonthebrain.bsky.social and more. Details 👇 careers.ucalgary.ca/jobs/1829278...careers.ucalgary.caAcademic Position in Neuromodulation Research, Department of Psychiatry, Cumming School of Medicine in Calgary, ...Academic Position in Neuromodulation Research, Department of Psychiatry, Cumming School of Medicine in Calgary, ... 0717
Reposted by Jeremy DayTaniel @taniel.bsky.social · 02/10/2026Voter registration deadlines are SUNDAY in Alaska, Rhode Island, South Carolina. And MONDAY in: Arizona, Arkansas Florida, Georgia, Indiana, Kentucky, Mississippi, Ohio, Tennessee, and *Texas*. If you live in these states, verify your registration now, literally. 2821431965
Reposted by Jeremy DayUAB Comprehensive Neuroscience Center @uabneuro.bsky.social · 01/10/2026Welcome to Dr. Barbara Juarez (@touchyourbrain.bsky.social) from the University of Maryland School of Medicine for the UAB Neuroscience Seminar Series today! 061
Jeremy Day @daylab.bsky.social · 30/09/2026A few days of seeing sunrises while fishing in Louisiana is a pretty good life reset hack. A massive yellowfin tuna catch also helps! 280
Reposted by Jeremy DayRobert Phillips @rphillips3.bsky.social · 27/09/2026Very excited to share our newest preprint, led by myself and Biostats PhD Student Jianing Yao, where we generate a three dimensional reconstruction of the human NAc to understand how cell type heterogeneity and topography change across the anterior-posterior axis. www.biorxiv.org/content/10.6... 14013
Reposted by Jeremy DayNature Portfolio @natureportfolio.nature.com · 23/09/2026A paper in Nature presents the largest-known map of gene expression in the human prefrontal cortex region of the brain. go.nature.com/46BFtJZ 🧬🧪 0227
Reposted by Jeremy DayJohn Timmer @jtimmer.bsky.social · 22/09/2026For non-developmental biologists: we don't think of ourselves as segmented (that's for insects, after all), but our nervous system is segmented. The forebrain is set up different than the midbrain, which is set up differently than the hindbrain, which is set up differently than the spinal cord. 422211
Jeremy Day @daylab.bsky.social · 18/09/2026Partial inspiration for this post was this excellent paper on long-range projections from another MGE-derived GABAergic cell type, Sst-Chodl neurons. www.nature.com/articles/s41...nature.comNeocortical long-range inhibition promotes cortical synchrony and sleep - NatureIn mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a cortical mechanism that co... 020
Jeremy Day @daylab.bsky.social · 18/09/2026#FluorescenceFriday Location of different classes of GABAergic interneurons derived from the medial ganglionic eminence in the mouse brain. Identified using the 10X Xenium platform, with @odrake.bsky.social and Jasper Heinsbroek. 1286
Jeremy Day @daylab.bsky.social · 18/09/2026Congratulations Jen! Excited to see all of the amazing science that comes out of this. 130
Jeremy Day @daylab.bsky.social · 17/09/2026Cool work from @edoncheck.bsky.social describing a platform for drug (or non-drug) self-administration combined with single-cell calcium imaging! www.nature.com/articles/s41...nature.comDrug self-administration in head-fixed mice - Nature ProtocolsHere, the authors provide a protocol for a head-restrained approach in mice for intravenous and oral self-administration of drug and nondrug rewards. 061
Jeremy Day @daylab.bsky.social · 16/09/2026Can confirm that it does not in fact end tomorrow - we will keep this open and review applications on a rolling basis! 120
Reposted by Jeremy DayLuke Sjulson @lukesjulson.bsky.social · 15/09/2026With the beginning of the new academic year, I'm reposting the info for our free online neuroscience methods course. If you're starting a PhD in neuroscience, or just want a refresher, this is for you! 0219
Reposted by Jeremy DayBernie Mulvey @berniejmulvey.bsky.social · 11/09/2026Excited to share work with cryostat wizard @heenadivecha.bsky.social looking at gene expression in my favorite brain region (LC) in adult postmortem brain! (Long URL to spare the trouble of identifying cars, buses, beds in 5x5 pixel imgs). (1/x) link.springer.com/epdf/10.1007...link.springer.comMolecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability 22516
Reposted by Jeremy DayAnthony Ramnauth @philoneurosci.bsky.social · 09/09/2026New publication from @lukesjulson.bsky.social lab and collaborators! #Neocortical long-range #inhibition promotes #cortical #synchrony and #sleep doi.org/10.1038/s415...doi.orgNeocortical long-range inhibition promotes cortical synchrony and sleep - NatureIn mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a cortical mechanism that co... 03713
Reposted by Jeremy Daydavidweinshenker.bsky.social @davidweinshenker.bsky.social · 08/09/2026Pleased to share a new Addiction Neuroscience Special Issue "Early Life Influences on Addiction" edited by @madrelabutd.bsky.social with contributions from @ericagrodin.bsky.social, @laurenmac.bsky.social, Marvin Diaz, Elizabeth Byrnes, and Chris Pierce! www.sciencedirect.com/special-issu...sciencedirect.com 0117
Reposted by Jeremy Day⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · 04/09/2026🚨🧠📄 @biorxivpreprint.bsky.social: L5 ACC engages dlPAG to facilitate affective pain First, map opioid+ pain ACC neurons: nature.com/articles/s4158… Next, ID endogenous opioid control across PAG: pmc.ncbi.nlm.nih.gov/articles/PMC11��� Now, we link the ACC→dlPAG circuit: biorxiv.org/content/10.648… 1183
Reposted by Jeremy DayUAB Comprehensive Neuroscience Center @uabneuro.bsky.social · 03/09/2026Glutamate is a major chemical messenger in the brain, and is fundamental for excitatory synaptic neurotransmission. This new discovery from CNC faculty members @jwadiche.bsky.social @wadichelabs.bsky.social reveals for the first time how glutamate concentration shapes glutamate receptor function.nature.comGlutamate concentration tunes AMPA receptor function through conductance-state occupancy - Nature NeuroscienceThis study shows that glutamate concentration at synapses can dynamically reshape how synaptic AMPA receptors pass current and calcium. This reveals a rapid way that synapses tune communication in the... 051
Reposted by Jeremy Daydavidweinshenker.bsky.social @davidweinshenker.bsky.social · 02/09/2026In case you missed the preprint the published version of our paper describing the cellular, molecular, and behavioral consequences of hyperphosphorylated tau in the mouse locus coeruleus is out! www.nature.com/articles/s41...nature.comPathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s disease - Molecular PsychiatryMolecular Psychiatry - Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s disease 2267
Reposted by Jeremy DayStephen V Mahler @svmahler.bsky.social · 31/08/2026New paper in @sfnjournals.bsky.social JNeurosci from Butcher, Ramirez, and Ruiz etal! We show that #addiction is not a unitary entity in the brain, and that even different opioid drugs recruit diff brain mechs. Highlighted in "this week in the Journal!" www.jneurosci.org/content/46/3...jneurosci.orgThis Week in The JournalHow Early-Life Stress Sensitizes Young Mice to Stressors Rebekah L. Rashford, Lisa Z. Fang, Michael DeBerardine, Hye Ji J. Kim, Laura W. Hirschfield, et al. (see article [e2217252026][1]) Adverse ... 193
Reposted by Jeremy DayNatalie Matosin @nataliematosin.bsky.social · 31/08/2026Stress can trigger symptoms in #schizophrenia. We've known that for decades, but not why. We found the chemical tags that keep the key stress gene #FKBP5 in check have worn away, leaving the #stress system switched on. Our latest in The American Journal of Psychiatry @apajournals.bsky.social 🧠psychiatryonline.orgPsychiatry OnlinePsychiatryOnline.org is the platform for all American Psychiatric Association Publishing journals, DSM, and bestselling textbooks, as well as APA Practice Guidelines, and continuing medical education. 1156
Jeremy Day @daylab.bsky.social · 31/08/2026New preprint from @u-bds.bsky.social outlines nf_xpatial, a Nextflow framework for reproducible processing of spatial transcriptomics data on the @10xgenomics.bsky.social Xenium platform. Happy to contribute a bit of our mouse brain data for this! www.biorxiv.org/content/10.6...biorxiv.orgnf_xpatial: A Reproducible Framework for Standardized Preprocessing and Clustering of Xenium DataRecent advances in spatial transcriptomics have enabled the profiling of increasingly larger numbers of genes while retaining single-cell and subcellular resolution in situ. However, standardized bioi... 070
Reposted by Jeremy DayJason Shepherd @jasonsynaptic.bsky.social · 28/08/2026My department is hiring! Come join a vibrant and thriving neuroscience group. New faculty are exceptionally well supported and we offer a very collaborative/collegial environment. employment.utah.edu/salt-lake-ci...employment.utah.eduFounded in 1850, The University of Utah is the flagship institution of higher learning in Utah, and offers over 100 undergraduate and more than 90 graduate degree programs to over 30,000 students. University of Utah Jobs 14440
Reposted by Jeremy DayUAB Comprehensive Neuroscience Center @uabneuro.bsky.social · 28/08/2026Feature story on the CNC's "Neuroscience for All" program, led by @visscherlab.bsky.social. This program uses hands-on demos to inspire an interest in neuroscience in our community. Read more below! www.uab.edu/reporter/in-...uab.eduWith bite-sized demos, UAB grad students inspire a taste for neuroscienceWith bite-sized demos, UAB grad students inspire a taste for neuroscience 021
Jeremy Day @daylab.bsky.social · 28/08/2026Thrilled to have an incredible keynote lecture from the Allen Institute’s @hongkuizeng.bsky.social for the @uabneuro.bsky.social annual retreat! Tools and cellular atlases generated by @alleninstitute.org provide a deep framework that serves as the foundation for mechanistic exploration. 0152
Reposted by Jeremy DayMichael Totty @mictott.bsky.social · 27/08/2026Incredibly proud to share our newest work where we developed a multiscale spatial transcriptomic atlas of the human amygdala using three complementary technologies! 1/12 🧵 www.biorxiv.org/content/10.6...biorxiv.orgMultiscale spatial transcriptomics resolves the cellular and molecular architecture of the human amygdalaThe amygdala is a central hub for emotional learning that is dysregulated across numerous psychiatric disorders, yet its molecular architecture in humans remains poorly defined. We here present a spat... 35225
Reposted by Jeremy DayReese Richardson @reeserichardson.bsky.social · 25/08/2026A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵 18455329
Reposted by Jeremy DaySfN Journals @sfnjournals.bsky.social · 13/08/2026Looking to improve your PeerReview skills? The Reviewer Mentor Program pairs trainees with #JNeurosci & #eNeuro editors & top reviewers to conduct strong manuscript reviews. Open to SfN members at any career stage: www.jneurosci.org/rmp 054
Reposted by Jeremy Daydavidweinshenker.bsky.social @davidweinshenker.bsky.social · 21/08/2026Important new paper on the role of LC mu opioid receptors in pain from @jordacular.bsky.social www.sciencedirect.com/science/arti...sciencedirect.com 0136
Reposted by Jeremy DayNature Reviews Neuroscience @natrevneuro.nature.com · 21/08/2026Early life experiences, the neural epigenome and affective disorder risk — a Review by Ashley M. Cunningham & Ian Maze #neuroscience #neuroskyence www.nature.com/articles/s41...nature.comEarly life experiences, the neural epigenome and affective disorder risk - Nature Reviews NeuroscienceUnderstanding how early life stress becomes biologically embedded remains a major challenge in neuroscience. In this Review, Maze and colleagues discuss recent advances in cell-type-specific epigeneti... 0185
Reposted by Jeremy DaySarah Yip @yiplab.bsky.social · 19/08/2026Looking for a postdoc in addiction and neuroimaging!! Check out medicine.yale.edu/biomedical-i... Message me directly if you are interested in hearing about opportunities to apply to work with the YIP lab :) 01518
Reposted by Jeremy DayDave Root @neuronroot.bsky.social · 18/08/2026On the cover of Science Signaling today, the final version of our initial investigation of functional differences between VTA glutamate-dopamine, nonglutamate-dopamine, and glutamate-only neurons www.science.org/doi/10.1126/...science.orgDistinct properties of glutamate-dopamine, nonglutamate-dopamine, and glutamate-only ventral tegmental area neuronsGlutamate cotransmission predicts the behavioral functions and characteristics of dopaminergic neurons in the VTA. 36119
Jeremy Day @daylab.bsky.social · 14/08/2026Quick #FluorescenceFriday post to show off these beautiful orexin neurons in the perifornical area of the lateral hypothalamus (red) in the rat brain. This small population of neurons plays a major role in regulation of sleep, feeding, and arousal. Image credit to @odrake.bsky.social 0241
Reposted by Jeremy DayFASEB @faseborg.bsky.social · 07/08/2026How does experience change the brain at the molecular level? The inaugural #NeuroExpSRC will bring together researchers studying experience-regulated transcription and neuronal plasticity to share the latest discoveries and build new collaborations. Find out more and register: buff.ly/qoyt0rWevents.faseb.orgHome - Neuronal Experience-Regulated TranscriptionExplore experience-regulated transcription in the brain, from mechanisms to disease links, at this inaugural neuroscience conference. 024
Reposted by Jeremy DayUAB Comprehensive Neuroscience Center @uabneuro.bsky.social · 12/08/2026Applications are open for the 2027 Scholar and Neurobiology of Brain Disorders Awards from the McKnight Foundation. Recent UAB awardees include Dr. Lillian Brady (2026 Scholar) and Dr. Jeremy Day (2022 NBDA awardee). Apply here: www.mcknight.org/programs/the...mcknight.orgNeurobiology of Brain Disorders Award-1200 022
Reposted by Jeremy DayKate Wassum @katewassum.bsky.social · 11/08/2026We’re hiring a research technician!! We’re an inclusive team of behavioral neuroscientists trying to discover the brain circuits of learning, decision making, and habit. More info👇 wassumlab.psych.ucla.edu/join-the-lab/ Job posting: jobs.ucla.edu/jobs/11232 13128
Reposted by Jeremy DaySteve Ramirez @okaysteve.bsky.social · 11/08/2026It was an honor to write this remembrance of Susumu Tonegawa (1939–2026) -- a scientist whose discoveries transformed biology and whose lab shaped generations of neuroscientists. I hope this piece captures even a small part of his remarkable legacy. www.nature.com/articles/s41...nature.comSusumu Tonegawa (1939–2026) - Nature NeuroscienceOn 11 July 2026, neuroscience lost one of its most visionary scientists with the passing of Susumu Tonegawa at the age of 86. Across an extraordinary career spanning more than five decades, Tonegawa p... 28727
Reposted by Jeremy Daydavidweinshenker.bsky.social @davidweinshenker.bsky.social · 10/08/2026Pleased to share a new Addiction Neuroscience Special Issue "The ventral pallidum as an orchestrator of reward seeking behavior" edited by Meaghan Creed with contributions from her, Anushree Karkhanis, @bensaunders.bsky.social, Asheeta Prasad, and Yvan Vachez www.sciencedirect.com/special-issu...sciencedirect.comAddiction Neuroscience | The ventral pallidum as an orchestrator of reward seeking behavior | ScienceDirect.com by ElsevierRead the latest articles of Addiction Neuroscience at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature 0178
Reposted by Jeremy DayRan Blekhman @blekhman.bsky.social · 09/08/2026Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9zv3rj... 3222232
Reposted by Jeremy DayTom Kash @superkash.bsky.social · 08/08/2026Hi Folks, with @lisataxier.bsky.social moving on to open her own lab at Stony Brook, I am in the market for a new postdoctoral fellow who wants to do slice electrophysiology. We have a number of really exciting projects, translational to basic science, that are ephys focused. 13939
Reposted by Jeremy DayNeuropsychopharmacology @npp-journal.bsky.social · 07/08/2026This study found opposing effects of fentanyl on tonic vs. phasic dopamine that may reveal insight on impaired non-drug reward seeking during opioid exposurenature.comAcute fentanyl induces opposing directions of changes in tonic and phasic dopamine release patterns and impairs Pavlovian task performanceNeuropsychopharmacology - Acute fentanyl induces opposing directions of changes in tonic and phasic dopamine release patterns and impairs Pavlovian task performance 0125
Jeremy Day @daylab.bsky.social · 07/08/2026Lot of dopamine papers/preprints on Bluesky this week - here is a fun #FluorescenceFriday image of a rat brain coronal section containing ventral tegmental area dopamine neurons, with nuclei in cyan and tyrosine hydroxylase protein (a marker of dopamine neurons) in red. Image by @odrake.bsky.social. 2403
Reposted by Jeremy DayDr. Cate Peña @cate-cholamine.bsky.social · 07/08/2026So proud to have “Early-life stress alters H3K4me1 in VTA to prime stress sensitivity” out now in Neuron! This work spanned Many years and Many people contributed. Huge thanks to @hyejaykim.bsky.social, @ja-balouek.bsky.social, Luke Geiger, and Meaghan Creed www.cell.com/neuron/fullt...cell.comEarly-life stress alters H3K4me1 in VTA to prime stress sensitivityKim, Geiger et al. report that early-life stress increases the chromatin modification H3K4me1 and its enzymatic writer, SETD7, in the ventral tegmental area. They show that this form of epigenetic pri... 89843
Reposted by Jeremy DayACNP @acnporg.bsky.social · 06/08/2026Please join us in Congratulating the 2026 ACNP Travel Award Class! 👏🤩 Click Here ➡️ tinyurl.com/5bzaz8va for more information on Travel Awards. 📝 14516