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Hongkui Zeng

@hongkuizeng.bsky.social
270 followers 2 following 5 posts

Director of Allen Institute for Brain Science

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Hongkui Zeng @hongkuizeng.bsky.social · 04/06/2026
This week’s launch of the #BrainHealth accelerator marks an important step forward for neuroscience. I’m excited to see this ambitious effort rally teams around a shared goal: building a deeper understanding of brain disease and accelerating progress toward better therapies.
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Hongkui Zeng @hongkuizeng.bsky.social · 08/03/2026
Excited to be part of #SRCKC26 this April in Kansas City. This year’s focus, Development, Regulatory Genomics & AI, highlights how regulatory DNA and AI-based sequence models are reshaping our understanding of gene expression and development. Join us: bit.ly/4kUvNAn
bit.ly
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Hongkui Zeng @hongkuizeng.bsky.social · 10/04/2025
It was a great pleasure to discuss why and how to study cell types in the human brain on The Transmitter.
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Hongkui Zeng @hongkuizeng.bsky.social · 10/04/2025
Spectacular work from the MICrONS project! We are learning so much from the amazingly detailed wiring diagram of the mouse visual cortex.
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Hongkui Zeng @hongkuizeng.bsky.social · 02/01/2025
Excited to share our single-cell study on aging mouse brain! We found 2,449 cell-type specific age-DE genes, and an aging hotspot in specific hypothalamic cell types involved in energy homeostasis, which show both decreased neuronal function and increased immune response. doi.org/10.1038/s415...
doi.org
Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice - Nature
A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional chan...
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