The ventromedial hypothalamus (VMH) and arcuate (ARC) nuclei of the hypothalamus play critical roles in regulating metabolism and behavior. Here, Mulvey et al. create a focused spatial transcriptomic ...

Cruz-Sanchez et al. show that the maturation trajectory of ventral and intermediate hippocampus-medial prefrontal cortex connectivity displays distinct anatomical and synaptic developmental signatures...

The heterogeneity of midbrain dopamine neurons is coming into focus. Distinct subtypes of dopamine neurons can be identified across the ventral tegmental area (VTA) and substantia nigra pars compacta ...

Single-cell transcriptomic analysis of mouse hypothalamus and behavioural experiments show that specific hypothalamic networks regulate conflicting feeding versus parenting behaviours of female mice.

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Neuropsychopharmacology - Neurobiology of resilience to early life stress

Neuropsychopharmacology - Prefrontal cortex development and its implications in mental illness

Drugs of abuse exert both motivational and emotional effects. Here, the authors show that nicotine and ethanol activate a VTA–NAc loop that inhibits dopamine neurons projecting to the amygdala, thereb...