Baertschi et al. demonstrate that microbiota transplantation functions as a selective ecological filter. Although donor species frequently appear, only specific lineages achieve stable strain integrat...

Nature Communications - Here, the authors provide evidence of the biotherapeutic potential of Klebsiella ARO112 for gut inflammatory conditions by showing it accelerates pathobiont clearance and...

Prebiotic, probiotic, and combined (synbiotic) interventions often show variable outcomes across individuals, driven by complex interactions between introduced biotics, the endogenous microbiota, and ...

Journal of Translational Medicine - The associations between a diet that associated with a healthy gut microbiota and the risk of frailty, as well as mortality in older adults with frailty, remains...

Variation among strains of a bacterial species is a powerful factor underlying the intensity of host responses during pathogenic infections. Less is known about the cellular and molecular responses of...

The One Health Microbiome Center will present the inaugural Microbiome Medal to Thomas Bosch on Dec 12. Bosch, a developmental biologist, zoologist and distinguished senior professor at Kiel Universit...

A bile acid-bound structure of toxin TcdB revealed the mechanism of inhibition and guided the design of a synthetic bile acid that alleviated Clostridioides difficile infection in mice.

Inflammatory bowel disease (IBD) is a chronic immune-mediated condition. This study presents a drug-free treatment strategy for IBD that targets bacterial adhesion, utilizing mannan oligosaccharide-lo...

Mass spectrometry data mining tools enabled the creation of an MS/MS spectral library containing hundreds of N-acyl lipids, including conjugates with short-chain fatty acids. This resource enabled the...

Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!

Nature Reviews Gastroenterology & Hepatology - The small intestinal microbiota has a key influence on digestion, immunity and nutrient metabolism but is poorly understood in comparison with the...

Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

Split-And-pool Metagenomic Plot-sampling sequencing (SAMPL-seq) can be applied to complex microbial communities to reveal spatial co-localization of microbes at the micron scale.

Metagenomic immunoglobulin sequencing (MIg-seq) uncovered patterns of IgA antibody binding of bacterial strains in the healthy human gut microbiome.

Diet has strong impacts on the composition and function of the gut microbiota with implications for host health. Therefore, it is critical to identify the dietary components that support growth of spe...

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Explore expert research on women’s health and microbiota development in children

In complex organisms, functional units must interact cohesively to maintain homeostasis, especially within mucosal barriers that house diverse, specia…

An observational longitudinal clinical trial, incorporating a SmartPill and metabolomics, reveals the role of host factors in shaping the gut microbiome in healthy human adults.

Dong et al. show that the avirulent C. difficile isolate ST1-75 outcompetes virulent C. difficile strains to protect mice from colitis, likely by depleting amino acids more efficiently. Because ST1-75 has a competitive advantage during coinfection, it has high biotherapeutic potential for preventing and treating recurrent C. difficile infections.

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The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...

Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.

First-of-its-kind platform will allow scientists to share tissues, organs, and other biological materials

Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...