A stool transplant delivers billions of microbes into a sick gut. Almost none move in for good.
We followed donor-recipient pairs from whole communities down to single nucleotides, and found the gut runs a ruthless strain-level filter.
Out now in Cell Reports 🧵
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Strain-level ecological filtering governs microbial colonization of the human gut
Baertschi et al. demonstrate that microbiota transplantation functions as a selective
ecological filter. Although donor species frequently appear, only specific lineages
achieve stable strain integrat...