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Andrew MacBride

@amacbride.com
3.8K followers 7.8K following 530 posts

biology + computers + a leavening of snark | 👨‍👨‍👧‍👧🏳️‍🌈| nanomedicine | cancer genomics 🧬 | ML | biomaterials | #compchem #matsky #chemsky #ai4science #materialsinformatics #md | startups | @Cal 🐻 @Stanford @UniversityOfOxford @OxfordNano (swimsf on the Bad Place)

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Reposted by Andrew MacBride
Marc Elias @marcelias.bsky.social · 08/10/2026
Today we got access to a smoking gun document from ICE that shows how it is weaponized against progressive groups registering voters while building a voter suppression database.
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twunktrapped by a 👻 @twunktrap.bsky.social · 02/09/2026
Studied all that software engineering just to be forced to become a condom between the Claude AI tool and the code.
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Sarah Andersen @sarahseeandersen.bsky.social · 01/08/2026
The image is of a four panel comic.
The first panel shows Sarah, the protagonist, as a child. Off panel, someone says to her, “Enjoy your youth!”
The second panel shows child Sarah again, now frowning. The person off panel continues, saying “After you’re 30 you’ll be old and your life will basically be over.”
Before the last two panels there is text that reads “LIFE AFTER I TURNED 30.”
The third panel shows adult Sarah opening a door.
The fourth panel shows the door opens to a beautiful field with flowers, a rainbow, and a pond. Sarah says “Wait what.”
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Melanie Lynskey @melanielynskey.bsky.social · 14/07/2026
I won an award at Sundance years ago and Sam Neill, whom I did not know, tweeted to me “we’re all so proud of you, sweetheart”. I can’t even express what that meant to me. That our most beloved national treasure, a man I worshipped, would take the time to write to me!
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Brendan @chemscrapes.bsky.social · 12/05/2026
Some orbitals have all the fun. #chemsky #chemchat
an s orbital, a p-orbital and a dx^2-y^2 orbital are all standing on the beach looking longingly at the dz^2 orbital playing with a beachball in the water.  the dz^2 orbitals are using their donut shaped lobe as a floatation device.
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Dmytro Mishkin @ducha-aiki.bsky.social · 06/05/2026
Yes.
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Andrew MacBride @amacbride.com · 06/05/2026
This was a fun project -- looking forward to the 2026 edition this fall. #compchem arxiv.org/abs/2605.03205
arxiv.org
From Knowledge to Action: Outcomes of the 2025 Large Language Model (LLM) Hackathon for Applications in Materials Science and Chemistry
Large language models (LLMs) are rapidly changing how researchers in materials science and chemistry discover, organize, and act on scientific knowledge. This paper analyzes a broad set of community-d...
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Andrew MacBride @amacbride.com · 26/04/2026
It’s honestly devastating to see everything laid out all together in this extremely important thread.
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Andrew MacBride @amacbride.com · 21/04/2026
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Andrew MacBride @amacbride.com · 05/04/2026
Well, this is delightful!
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Terry McGlynn @hormiga.bsky.social · 09/03/2026
Hey fellow scientists, I'm just letting you know that if you're promoting something with some junky AI image, I'm not gonna click. You've got a workshop, a conference, a new paper? Just not gonna bother. You want a bespoke image? Hire an illustrator.
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Tressie McMillan Cottom @tressiemcphd.bsky.social · 24/02/2026
Henceforth, I will be describing the way that U.S. men’s hockey spectacularly squandered good will, brand recognition, and fan loyalty as “pulled a Target.” They pulled a Target.
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Edward Nirenberg @enirenberg.bsky.social · 11/02/2026
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines. apnews.com/article/mode...
apnews.com
Moderna says FDA refuses its application for new mRNA flu vaccine
The U.S. Food and Drug Administration is refusing to consider Moderna’s application for a new flu vaccine made with mRNA technology.
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George Takei @georgetakei.bsky.social · 27/01/2026
After being held in two of them as a boy, I fought for decades urging America to never again build concentration camps and put human beings in them. It breaks my heart to watch this happen twice now in my own lifetime.
Screenshot of an X.com post by The Associated Press (@AP) stating that dozens of immigrant families protested for better treatment behind fences at a Texas detention facility, where a 5-year-old Ecuadorian boy and his father were sent after being detained in Minnesota. Below is a video thumbnail showing a crowd gathered outdoors along a fenced walkway; many people wear bright blue or red outerwear, and some hold signs.
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Katie Mack @astrokatie.com · 25/01/2026
A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.
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Monstro ElisaDrew @radliftist.bsky.social · 24/01/2026
Abolish ICE. Arrest and try them all, starting with Noem
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Katie Phang @katiephang.bsky.social · 22/01/2026
Special Counsel Jack Smith in his Opening Remarks:
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Aaron Rupar @atrupar.com · 22/01/2026
Jack Smith: "My fear is that we have seen the rule of law function in our country for so long that many of us have come to take it for granted. The rule of law is not self-executing. It depends on our collective commitment to apply it."
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Musicology Duck @musicologyduck.bsky.social · 20/01/2026
I just woke up from a nap and somehow while I was asleep, everyone on the bus has figured out we are not going to the right place
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Stephen Turner @stephenturner.us · 20/01/2026
Prime numbers 2-4999, animated with ggplot2+gganimate. #Rstats code: gist.github.com/stephenturne...
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lastpositivist.bsky.social @lastpositivist.bsky.social · 11/01/2026
If I was the commander in chief of the Imperial hegemon I would simply not dismantle the network of military and diplomatic alliances, favourable trade deals, and broad cultural paramountcy that had made my nation the most wealthy and powerful the world has ever seen.
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Joe C. @heyjoec.bsky.social · 11/01/2026
Going to tell my kids this is Heat Miser #TheTraitors
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Chris @chrispaget1.bsky.social · 11/01/2026
Me casting resurrection magic to get up for work this morning
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Caroline Lynn Kamerlin ☀️ @lynnkamerlin.bsky.social · 11/01/2026
Iran has been under communications blackout for over 60 hours now. Several thousand people have been killed (numbers vary by source, I have seen between 2 and 5000 this morning). Iranians abroad don't know if their loved ones are alive or dead, have absolutely no way to communicate 1/
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Jon 🎄 @pifflevalve.eurosky.social · 30/12/2025
The sensible thing to do next week would be to return to work with a can-do attitude, value teamwork and leverage synergies to contribute to the value stream, but fucking hell there must be a better way to spend this limited time on earth
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Andrew MacBride @amacbride.com · 20/12/2025
Something a little different for this pre-holiday weekend, as we roll towards the end of the year. I did this as part of my MSc thesis, to add a little variety to my hobby of "staring at molecules." #compchem Code is on GitHub at: github.com/amacbride/sk... Enjoy! Have a great holiday.
OpenGL "pen-and-ink" rendering of a lysine molecule on brown paper.
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C. Robert Cargill @crobertcargill.bsky.social · 15/12/2025
The cultural impact of Rob Reiner cannot be understated. Legend isn't big enough a word. It goes to 11. You can't handle the truth. As you wish. I'll have what she's having. I'm your number one fan. You guys wanna see a dead body? The very idea of a bucket list. The West Wing. All from his movies.
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Erin Biba @erinbiba.bsky.social · 14/12/2025
Steve isn’t here anymore, but he always posted this picture on Hanukkah so I thought we could carry on his tradition and remember him.
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alix e. harrow @alixeharrow.bsky.social · 12/12/2025
imagine trying to convince me that I should "get used" to AI bc it's "here to stay." honey mitch mcconnell has been my senator since before i was born, do you think i don't know how to lock in and hate for the long haul
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Thor Benson @thorbenson.bsky.social · 12/12/2025
I guess it's fitting that it's a reimagined, worse version of someone else's artwork
Time person of the year cover for 2025
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Michael Merrifield @astromikemerri.bsky.social · 11/12/2025
What’s the difference is between an astronomer and an astrophysicist? If you’re on a long-haul flight and the person in the next seat asks what you do, you tell them you’re an astronomer if you want to spend the next 4 hours talking to them, or an astrophysicist if you want to get some sleep. 🔭
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Andrew MacBride @amacbride.com · 10/12/2025
It still boggles my mind that AWS took a perfectly useful batteries-included distro like Amazon Linux (1/2) and completely neutered it.
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Andrew MacBride @amacbride.com · 06/12/2025
A bit of personal news: I found out this morning that my MSc dissertation was accepted!
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Sebastian S. Cocioba @atinygreencell.bsky.social · 04/12/2025
Being curious in a universe that seems indifferent to our existence is such a cosmic flex. Laughing, loving, and learning as ephemeral beings in the void, in open rebellion to a world that wants us dead, is so beautifully human. Science as gallows humor, lol.
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Robert Shrimsley @robertshrimsley.bsky.social · 29/11/2025
Perfect Tom Stoppard story from DTel obituary: His response to a letter from Harold Pinter canvassing support for a proposal to have the Comedy Theatre in London rechristened the Pinter Theatre, “Have you thought, instead, of changing your name to Harold Comedy?”
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Harmit Singh Malik @harmitmalik.bsky.social · 01/12/2025
The day after Thanksgiving break. Time to take stock. Am I really going to make a dent in this to-do list before leaving for Christmas/New Year vacation? What do you say, 8-ball?
media.tenor.com
woody from toy story sits on the floor next to a black ball with the number 8 on it
Alt: Woody the cowboy from the Toy Story movie sits on the floor and picks up an 8-ball and the answer comes up "Don't count on it"
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Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 02/12/2025
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n
quinlanlab.org
Intro to Bedder – The Quinlan Lab
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Brian McNoldy @bmcnoldy.bsky.social · 30/11/2025
The 2025 Atlantic Hurricane Season officially ends today. Overall, it was a slightly above-average season with some strange characteristics. [1/4]
bmcnoldy.blogspot.com
Summary of the Unusual 2025 Hurricane Season
Updates and summaries on tropical Atlantic activity... including easterly waves, tropical storms, subtropical storms, and hurricanes.
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Matt Hartings @matthartings.bsky.social · 29/11/2025
That's the story. Nothing else matters.
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Dave Levitan @davelevitan.bsky.social · 29/11/2025
words, what do they mean www.washingtonpost.com/health/2025/...
“I remain open to vigorous discussions and debate,” Prasad wrote to his team, adding that staff who did not agree with the core principles of his new approach should submit their resignations.
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Department of Chemistry, Stanford University @stanfordchemistry.bsky.social · 26/11/2025
Prof. Laura Dassama (Stanford Chem) is developing a small-molecule therapy for sickle cell disease that removes BCL11A, restoring fetal hemoglobin without gene editing. Her goal is a simpler, more affordable sickle cell therapy. brnw.ch/21wXP8k
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Andrew MacBride @amacbride.com · 27/11/2025
When there was that *one year* long ago when we forgot to get the turkey bag…
So many turkey bags….
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Smut Clyde, X-Ray Haruspex @smutclyde.bsky.social · 26/11/2025
Rate your score on Factor Fexcectorn. Well done, Scientific Reports. pubpeer.com/publications...
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Derek Lowe @dereklowe.bsky.social · 24/11/2025
xkcd.com/3172/
xkcd.com
Fifteen Years
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Ben Blaiszik @benblaiszik.bsky.social · 24/11/2025
TorchSim continues its growth aiming to be the high-performance engine for MLIP-powered atomistic simulation. With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.
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Scott Bagley @bagphos.bsky.social · 24/11/2025
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Katie Mack @astrokatie.com · 20/11/2025
Can’t believe the whole country has to suffer through the return of Dickensian childhood diseases because the worst, most ignorant attention-demanders decided other people’s expertise makes them feel bad
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Stephen Turner @stephenturner.us · 17/11/2025
Complex de novo structural variants are an underestimated cause of rare disorders www.nature.com/articles/s41...
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Georgia Alison Marchant 🏳️‍⚧️ 🇵🇸 @gamarchant.bsky.social · 14/11/2025
I can’t believe this monumental paper has finally been published! Congrats to all the very many brilliant researchers involved, including @molecularxtal.bsky.social and @jrkermode.co.uk 😃 What an exciting step in computational chemistry this represents! pubs.aip.org/aip/jcp/arti...
pubs.aip.org
A foundation model for atomistic materials chemistry
Atomistic simulations of matter, especially those that leverage first-principles (ab initio) electronic structure theory, provide a microscopic view of the worl
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Nessa Carson @supersciencegrl.co.uk · 11/11/2025
I had the option of getting this comp chem book as a physical book or an eBook. Normally I read pdfs on Kindle, and the eBook cost less, so I went with that. They have now sent me a link to an awkward, locked-down platform called VitalSource. I have regrets 😂 I'll know for next time...
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