BPZE1 was well tolerated in children aged 6–17 years, and induced robust nasal S-IgA responses to B pertussis WCE without interference from simultaneously administered Tdap. BPZE1 vaccination did not interfere with Tdap-induced serum IgG to B pertussis antigens and tetanus and diphtheria toxoids. These findings support further development of BPZE1 as a vaccine candidate against pertussis in acellular pertussis vaccine-primed children 6 years and older.

Pathologists and radiologists spend years acquiring and refining their medically essential visual skills, so it is of considerable interest to understand how this process actually unfolds and what ima...

US biomedical agency no longer considers policymakers as ‘mission relevant’, leaving dozens of grants in limbo.

The University of Oxford’s Oxford Vaccine Group has today successfully vaccinated the first volunteer in the world’s first clinical trial of a vaccine designed to protect against Bundibugyo ebolavirus...

Key Points. IgA and IgM human plasma cells express a functional BCR on their cell surface and can therefore respond to antigenic stimulation.

Some nucleotides have been shown to control metabolism by ‘gluing’ proteins together. Could other small molecules made naturally by cells have similar capabilities?

NFID is pleased to announce the 2026-2027 NFID Board of Directors and leadership team.

Past outbreaks spawned clever strategies for testing antivirals and antibodies, but researchers will still face major challenges on the ground

Background: There are currently no vaccines approved for the prevention or treatment of Orthoebolavirus bundibugyoense (Bundibugyo virus; BDBV). The recombinant vesicular stomatitis virus- Zaire ebola...

A Review of the immunological mechanisms of mRNA–lipid-nanoparticle vaccines for infectious diseases discusses how the components of this vaccine platform can be modified to fine-tune immune responses...

Gabbard’s declassification theater is a case study in politicizing intelligence.

The government’s delays renewing in-progress research are leaving researchers in limbo.

Nature Reviews Immunology, Published online: 22 June 2026; doi:10.1038/s41577-026-01329-8A preprint by Hu et al. shows, in a mouse model of primary tauopathy, that conventional type 1 dendritic cells outside of the central nervous system prime CD8+ T cells against brain-derived antigens, which exacerbate neurodegeneration.

The study found that the vaccine reduced the risk of emergency department visits and hospitalizations among healthy adults by about half last winter.

Two probable cases of sexual transmission of Marburg virus are reported from the 2024 outbreak in Rwanda, both following condomless sexual contact with male partners who recovered from the disease, bu...

At every stage of childhood, the Trump administration is withdrawing a protection. It is also dismantling the tools that would measure the harm