Anoxic live-cell imaging shows actin-dependent crawling motility and dynamic protrusions in Asgard archaea, providing insights into cellular innovations that may have contributed to eukaryotic evoluti...

This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…

Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...

This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…

Nature Communications - Almeida AC et al. uncover the physiological role of a long-elusive feedback pathway that regulates tubulin biosynthesis. By tuning microtubule dynamics, this mechanism...

Almeida AC et al. uncover the physiological role of a long-elusive feedback pathway that regulates tubulin biosynthesis. By tuning microtubule dynamics, this mechanism preserves cell adhesion, surviva...

A prototype cell partly capable of replicating itself has been created using 36 existing bacterial genes, but it's not really a living organism – yet

YouTube video by Cell Press

Living Architectures - Case studies

Cells mechanically interface with their surroundings through the actin cytoskeleton, a network of dynamic actin filaments, force-generating myosin motor proteins, and hundreds of associated binding pr...

Dr. Thomas D. Pollard's work transformed cytoskeleton research into a quantitative, mechanistic science. Over five decades, he established core principles of actin dynamics, including filament polari....

Multinucleate cells — single cells containing multiple nuclei in a shared cytoplasm — are found across the eukaryotic tree of life. Having evolved ind…

Pour se déplacer, les fibroblastes émettent une structure large et plate au niveau de leur pôle antérieur, le lamellipode.

Structural studies demonstrate that myosin generates forces that cause structural changes in actin, modulating cooperative binding by α-catenin and thus signal transduction and intercellular communica...

YouTube video by CNRS

The 2026 Gordon Research Conference on Cytoskeletal Motors will be held in Portland, Maine. Apply today to reserve your spot.

Chez les plantes, les cellules ne peuvent ni se déplacer ni se réorganiser librement en raison de leur paroi rigide.

Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is know...

À l’automne 2025, un rapport déposé au Sénat auquel le CNRS a contribué a proposé plusieurs mesures fortes pour attirer et consolider les effectifs féminins d

Nature Microbiology - During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of...

À l'occasion d'un projet de documentaire radio sur France Culture, je cherche des chercheur-ses représentant une diversité de disciplines mais également de statuts à interviewer. L'idée est de partir...

En utilisant la microscopie de fluorescence résolue en polarisation, les biologistes et physiciens de l'Institut Fresnel, associés à une équipe internat