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Surrey Lab

@surreylab.bsky.social
216 followers 207 following 9 posts

Thomas Surrey's lab @crg.eu MICROTUBULES | Molecular Biochemistry | In vitro Reconstitutions 🦋 posts by lab members

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Reposted by Surrey Lab
Iva Tolić @ivatolic.bsky.social · 12/04/2026
Wei Ming Lim from the Surrey lab @surreylab.bsky.social reconstituted fluxing anaphase-like mini-spindles by using only 4 purified proteins: tubulin, PRC1, KIF4A, and kinesin-5. #SpindleCroatia2026
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Surrey Lab @surreylab.bsky.social · 24/04/2026
And Zoë from our lab defended her PhD! 🎉 She’s been uncovering microtubule organization and mitotic spindle assembly using a little pet she created: the spider kinesin 🕷️ What, you’ve never heard of it? Stay tuned for what’s coming next! Congratulations Zoë!!! 👏🎓
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Reposted by Surrey Lab
Parc de Recerca Biomèdica de Barcelona @prbb.org · 27/10/2025
📣 New PRBB-CRG conference 📋 Dynamics and structural changes within the microtubule lattice 🗣️ @kjverhey1.bsky.social - University of Michigan Medical School 📆 Oct 31 - ⏰ 12:00 hosted by: @surreylab.bsky.social - @crg.eu    📍 #PRBB Marie Curie room
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Surrey Lab @surreylab.bsky.social · 23/10/2025
⚡Ready to grow and be inspired as a scientist? We’re looking for a *PhD student* to join our lab at @crg.eu in Barcelona and explore how cells self-organize, uncovering life’s inner design💡 We offer strong mentoring, cutting-edge science, and a vibrant international team🌍 Check the link below!
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Reposted by Surrey Lab
Centre de Regulació Genòmica (CRG) @crg.eu · 23/10/2025
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...
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Reposted by Surrey Lab
Centre de Regulació Genòmica (CRG) @crg.eu · 30/05/2025
Endinsa’t en una vivència sensorial única que connecta ciència i art immersiu. “SEEING: Un ull i una caixa” arriba del 5 al 14 de juny al Centre Cívic Convent de Sant Agustí (Carrer del Comerç 36, Barcelona). www.crg.eu/en/event/see...
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Surrey Lab @surreylab.bsky.social · 23/04/2025
🚀 Ready for inspiring talks, sunshine, and great company in Barcelona from 22–25 September 2025? Don’t miss your chance to be part of it! Sign up here: forms.creacongresos.com/DivIDE/
forms.creacongresos.com
3rd DivIDE Conference
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Surrey Lab @surreylab.bsky.social · 26/03/2025
🚨New paper out @pnas.org! Do you want to know how do mitotic motors organize the spindle? Wei Xiang's simulations show that just a plus & a minus motor are enough to drive bipolar spindle assembly. Could this explain why kinesin-5 & dynein evolved their unique properties? 🤔 doi.org/10.1073/pnas...
pnas.org
Molecular design principles for bipolar spindle organization by two opposing motors | PNAS
During cell division in animal cells, a bipolar spindle assembles to segregate the chromosomes. Various motor proteins with different properties ar...
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Surrey Lab @surreylab.bsky.social · 11/03/2025
We're on a roll!🚀 Check our latest research @naturecomms.bsky.social: rdcu.be/ecXzr We reveal how mosaic MTs faithfully mimic the GTP cap, highlighting lattice expansion (not pf twist) as the structural cornerstone of MT stability and dynamic instability. Congrats to Juan and everybody involved! 🎉
rdcu.be
Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap
Nature Communications - Estévez Gallego et al. present a study demonstrating that mosaic microtubules consisting of a mix of GTP hydrolysis-deficient tubulin mutants are faithful microtubule...
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Surrey Lab @surreylab.bsky.social · 12/02/2025
Also, huge congrats to Sabina @bilirubina.bsky.social for not only publishing her work in JCB but also successfully defending her PhD thesis last Friday! 🎉 We're so proud of all you've accomplished over the past few years and excited to see what amazing things you will do next, Dr. Sabina! 🥳
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Surrey Lab @surreylab.bsky.social · 12/02/2025
Fresh off the press! 🔬 Our team's new publication in the JCB sheds light on the intricate dance of spindle proteins and microtubules! 🕺💃Sabina (@bilirubina.bsky.social) demonstrates that NuMA acts as a mitotic dynein adaptor, binding and capping minus ends to focus them at mitotic spindle poles!
buff.ly
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends | Journal of Cell Biology | Rockefeller University Press
Using microscopy-based in vitro reconstitutions, Colombo et al. show that NuMA is a mitotic dynein adaptor that binds and caps microtubule minus ends, expl
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