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Jeroen Bakkers

@bakkerslab.bsky.social

643 followers 107 following 19 posts

We study cardiac development, disease and regeneration and are located at the Hubrecht Institute in The Netherlands

Posts Replies Media

Reposted by Jeroen Bakkers

Francesca Mattiroli @fmattiroli.bsky.social · 01/04/2026

Looking forward to starting a new project with @bakkerslab.bsky.social to learn how chromatin changes to allow regeneration in the heart.

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Jeroen Bakkers @bakkerslab.bsky.social · 27/03/2026

I am happy and excited to share our latest preprint on PLN cardiomyopathy: www.biorxiv.org/cgi/content/... We found that PLN R14del cardiomyocytes have lysosomal dysfunction resulting in PLN accumulation, microtubule remodelling and structural defects, which are rescued by lysosomal reactivation.

PLN accumulates in aged PLN R14del zebrafish hearts, which is resolved by fasting-induced lysosomal activation

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Reposted by Jeroen Bakkers

Hubrecht Institute @hubrechtinstitute.bsky.social · 26/03/2026

How is epigenetic information propagated during development? How do chromosomes reorganize DNA through the cell cycle? And how can cutting-edge imaging capture developmental machines and processes? These were just some of the questions explored at #HubrechtSymposium2026. Thanks for joining today!

Alejandro Cardona Monzonis presenting his poster

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Jeroen Bakkers @bakkerslab.bsky.social · 23/05/2025

We are hiring a new PhD student in #Bioinformatics and Organ #Regeneration using to join our team at the @hubrechtinstitute.bsky.social If you are interested in how the heart regenerates and want to work in a dynamic and experienced team please apply here. www.hubrecht.eu/job/phd-stud...

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Jeroen Bakkers @bakkerslab.bsky.social · 14/03/2025

The first Hubrecht symposium was great opportunity to hear about fundamental research and it was a pleasure to participate in it 👏

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Jeroen Bakkers @bakkerslab.bsky.social · 22/01/2025

Thanks for hosting me @merln-um.bsky.social Enjoyed the interactions with staff and students on new approaches for #regeneration #research

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Reposted by Jeroen Bakkers

Weinstein Conference @weinsteinconf.bsky.social · 14/01/2025

Calling all cardiovascular scientists.... @WeinsteinConf is in Milwaukee May 14-16! Abstract submission now open. Registration portal is imminent! childrenswi.org/weinstein Are you a trainee and want to be considered for a platform talk - abstract due Feb 21!

childrenswi.org

Weinstein Cardiovascular Development and Regeneration Conference | 2025. Online registration by Cvent

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Jeroen Bakkers @bakkerslab.bsky.social · 03/01/2025

🫀 Zebrafish protein unlocks dormant genes for mammalian heart repair. Our work published by @springer1842.bsky.social in Nature CVR uncovers how the protein HMGA1 could unlock mammalian heart repair. rdcu.be/d5owa #HeartHealth #Regeneration #Biomedicine #Cardiology

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Reposted by Jeroen Bakkers

Hubrecht Institute @hubrechtinstitute.bsky.social · 02/01/2025

Researchers from @bakkerslab.bsky.social have successfully repaired damaged mouse hearts using a protein from zebrafish. This study marks a promising step toward regenerative therapies to prevent heart failure. Curious? www.hubrecht.eu/zebrafish-pr... @marabouwman.bsky.social l

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Jeroen Bakkers @bakkerslab.bsky.social · 23/12/2024

Great work showing the power of interspecies comparison to reveal new mechanisms for tissue regeneration!

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Reposted by Jeroen Bakkers

Dominic Grün @dominicgrun.bsky.social · 16/11/2024

Excited to share our study on spatio-temporal reconstruction of cardiac scar formation led by Andy Chan. We combine scRNA-seq with spatial transcriptomics to resolve the fibrotic niche and the niche of dedifferentiating cardiomyocytes. www.biorxiv.org/content/10.1...

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