Genomic therapy offers a promising strategy for addressing central nervous system disorders. This Review highlights recent advances in chemical strategies and delivery platforms, such as lipid nanopar...

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Nature Nanotechnology - This work presents a degradable ionizable lipid, AMG1541, for mRNA vaccines that significantly enhances potency and enables similar protective immunity at doses 100-fold...

mRNA has emerged as an important class of therapeutic molecules. Now, an artificial intelligence (AI)-driven framework, which can design mRNA sequences with enhanced stability and translational effici...

Nature Reviews Drug Discovery - Lipid nanoparticle-based systems are increasingly being utilized for the delivery of nucleic acid-based vaccines and therapeutics. In this Perspective, Cullis and...

NY-CURES is working to advance bold, state-backed investment in biomedical research—on the scale of successful initiatives in California and Texas—to grow New York’s leadership in science, innovation, and health.

Use AIMBE's letter template below to send an email to your Members of Congress on issues that matter. We encourage you to edit and personalize the note, sharing your individual experience. Please note...

An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and develop...

Shruti Naik, an immunologist and a strong advocate for diversity in science, has joined forces with Aaron Mertz, who leads programmes that help to explain, connect and maximize the benefits of science...

A combination of engineering approaches is used to improve the function of IscB for a variety of editing activities in vivo.

Delivery of mRNA (mRNA) to the central nervous system (CNS) remains a significant challenge. Herein, we design a library of furan-derived lipids and, to our knowledge, for the first time, leverage the...

Monoclonal antibody (mAb) therapeutics have become widely successful for treatment of any number of diseases. However, for certain hard-to-reach tissu…

Nature Nanotechnology, Published online: 15 April 2025; doi:10.1038/s41565-025-01878-4A nanoporous photocatalyst producing low levels of hydrogen peroxide is shown to modulate intracellular stress granules, enhancing resilience against oxidative stress and providing cardioprotection in an ex vivo rodent model of myocardial ischaemia–reperfusion injury.

Dendritic cells (DCs) are essential for inducing effective antitumor T cell responses. However, the immunosuppressive tumor microenvironment (TME) hin…

A compelling new study adds to the body of data supporting some protection provided by the vaccine

Neuroscience institutes tells 10 scientists placed on leave it’s working on a “long-term” solution to officially reinstating them

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The reasons for selecting these researchers—who have led work on neuronal migration, dopamine receptors in neuronal signaling and the structure of ion channels, among other areas—remain unclear.